摘要: Abstract: To face the challenges of keeping healthy in increasing population sizes of
both ageing and developing people in China, a fundamental request from the public
health is the development of lifespan normative trajectories of brain and behavior. This
paper introduces the Chinese Color Nest Project (CCNP 2013–2022), a large-scale tenyear
program of modeling brain and behavioral trajectories for human lifespan (6–85
years old). We plan to gradually collect the behavioral and brain imaging data at ages
across the lifespan on nationwide and depict the normal trajectory of Chinese brain
development across the lifespan, based on the accelerated longitudinal design in the
coming next 10 years starting at 2013. Various psychiatric disorders have been
demonstrated highly relevant to abnormal events during the neurodevelopment regarding
their onset ages of first episodes. Therefore, delineation of normative growth curves of
brain and cognition in typically developing children is extremely useful for monitoring,
early detecting and intervention of various neurodevelopmental disorders. In this paper,
we detailed the developing part of CCNP, devCCNP. It tracked 192 healthy children and
adolescents (6–18 years old) in Beibei district of Chongqing for the first 5 years of the
full CCNP cohort (2013–2017). To demonstrate the feasibility of implementing the longterm
follow-up of CCNP, we here comprehensively document devCCNP in terms of its
experimental design, sample strategies, data acquisition and storage as well as some
preliminary results and data sharing roadmap for future. Specifically, we first describe the
accelerated longitudinal sampling design as well as its exact ratio of sample dropping off
during the data collection. Second, we present several initial findings such as canonical
growth curves of cortical surface areas of a set of well-established large-scale functional
networks of the human brain. Finally, together with records generated by many
psychological and behavioral tests, we will provide an individual growing-up report for
each family participating the program, initiating the potential guidance on the individual
academic and social development. The resources introduced in the current work can
provide first-hand data for a series of coming Chinese brain development studies, such as
Chinese Standard MRI Brain Templates, Normative Growth Curves of Chinese Brain and
Cognition as well as Mapping of Language Areas in Chinese Developing Brain. These
would not only offer normative references of the atypical brain and cognition
development for Chinese population but also serve as a strong force on accelerating the
pace of integrating Chinese brain development into the national brain program or Chinese
Brain Project.
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期刊:
Chinese Science Bulletin
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分类:
心理学
>>
实验心理学
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引用:
ChinaXiv:201710.00010
(或此版本
ChinaXiv:201710.00010V1)
DOI:10.1360/N972017-00362
CSTR:32003.36.ChinaXiv.201710.00010.V1
- 推荐引用方式:
Ning Yang,Ye He,Zhe Zhang,Hao-Ming Dong,Lei Zhang,Xing-Ting Zhu,Xiao-Hui Hou,Yin-Shan Wang,Quan Zhou,Zhu-QingGong,Li-Zhi Cao,Ping Wang,Yi-Wen Zhang,Dan-Yang Sui,TingXu1,Gao-Xia Wei,Zhi Yang,Lili Jiang,Hui-Jie Li,Ting-YongFeng,Antao Chen,Jiang Qiu,Xu Chen,Xun Liu,Xi-Nian Zuo.(2017).Chinese Color Nest Project (CCNP)i: Growing Up in China.Chinese Science Bulletin.doi:10.1360/N972017-00362
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