分类： 光学 >> 量子光学 提交时间： 2023-02-19
摘要： The crucial zeroth-order light due to the pixelation effect of spatial light modulator (SLM) has been a serious issue in the field of light modulation, especially in applications with a high numerical aperture optical system. In this investigation, we report that by properly adjusting the high-level and low-level pixel voltages of an SLM, the zeroth-order light caused by the pixelation effect of SLM can be significantly eliminated. The method is further validated in an inverted fluorescence microscope. The experimental results show that the zeroth-order light can be inhibited up to 91.3%, accompanied by an improvement of the modulation efficiency from 77.5% to 92.6%.
分类： 光学 >> 量子光学 提交时间： 2023-02-19
摘要： Computational ghost imaging or single-pixel imaging enables the image formation of an unknown scene using a lens-free photodetector. In this Letter, we present a computational panoramic ghost imaging system that can achieve the full-color panorama using a single-pixel photodetector, where a convex mirror performs the optical transformation of the engineered Hadamard-based circular illumination pattern from unidirectionally to omnidirectionally. To our best knowledge, it is the first time to propose the concept of ghost panorama and realize preliminary experimentations. It is foreseeable that ghost panorama will have more advantages in imaging and detection in many extreme conditions (e.g., scattering/turbulence, cryogenic temperatures, and unconventional spectra), as well as broad application prospects in the positioning of fast-moving targets and situation awareness for autonomous vehicles.
分类： 光学 >> 量子光学 提交时间： 2023-02-19
Yanyan Gong
Ming Zeng
Yueqiang Zhu
Shangyu Li
Wei Zhao
Ce Zhang
Tianyun Zhao
Kaige Wang
Jiangcun Yang
Jintao Bai
摘要： Flow cytometry is a widespread and powerful technique, whose resolution is determined by its capacity to accurately distinguish fluorescently positive populations from negative ones. However, most informative results are discarded while performing the measurements of conventional flow cytometry, e.g., the cell size, shape, morphology, and distribution or location of labeled exosomes within the unpurified biological samples. We, herein, propose a novel approach using an anti-diffraction light sheet with anisotroic feature to excite fluorescent tags. Constituted by an anti-diffraction Bessel-Gaussian beam array, the light sheet is 12 \mum wide, 12 \mum high, with a thickness of ~ 0.8 \mum. The intensity profile of the excited fluorescent signal can, therefore, reflect the size and allow samples in the range from O(100 nm) to 10 \mum (e.g., blood cells) to be transported via hydrodynamic focusing in a microfluidic chip. The sampling rate is 500 kHz provides a capability of high throughput without sacrificing the spatial resolution. Consequently, the proposed anti-diffraction light-sheet flow cytometry (ADLSFC) can obtain more informative results than the conventional methodologies, and is able to provide multiple characteristics (e.g., the size and distribution of fluorescent signal) helping to distinguish the target samples from the complex backgrounds.
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