Progress of Synthetic Biology Research in Medical Applications

Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-03-19 Cooperative journals: 《中国科学院院刊》

崔金明 王力为 常志广 臧中盛 刘陈立

Abstract： In the field of medical applications, synthetic biology researchers design genetic circuits to modify human cells, or to modify synthetic organisms such as bacteria and viruses and make them interact with the human body. These artificially designed organisms are capable of perceiving disease-specific signals or artificial signals, targeting abnormal cells and foci, expressing reporter molecules or releasing therapeutic drugs, thus enabling the monitoring of human physiological conditions and the diagnosis and treatment of typical diseases such as tumors, metabolic diseases, and drug-resistant bacteria infections. This article will comprehensively describe some recent research progress.

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