Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-03-19 Cooperative journals: 《中国科学院院刊》
Abstract： In the field of synthetic biology research, the massive scale of trial-and-error experiments in engineering goes far beyond the traditional labor-intensive research paradigm, so it needs a transformative engineering research platform. With the introduction of various types of intelligent equipment to meet the production needs, engineering platforms carry out a large-scale of customization and research paradigm innovation, to realize the remote customization, offsite design, and economic scale production of organisms. Engineering platforms can accumulate experience and knowledge quickly, and serve as the scientific basis for the predictive synthesis of organisms. This article will introduce some cases and development trends of engineering platforms, as well as upstream and downstream institutions for synthetic biology research.
Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-03-19 Cooperative journals: 《中国科学院院刊》
Abstract： In the field of medical applications, synthetic biology researchers design genetic circuits to modify human cells, or to modify synthetic organisms such as bacteria and viruses and make them interact with the human body. These artificially designed organisms are capable of perceiving disease-specific signals or artificial signals, targeting abnormal cells and foci, expressing reporter molecules or releasing therapeutic drugs, thus enabling the monitoring of human physiological conditions and the diagnosis and treatment of typical diseases such as tumors, metabolic diseases, and drug-resistant bacteria infections. This article will comprehensively describe some recent research progress.
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