分类： 核科学技术 >> 核材料与工艺技术 提交时间： 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要： This study investigated the impact of simulated microgravity on acute injury induced by low doses of carbon ions in male reproductive organs of mice, and determined alterations in spermatogenic function and expression levels of apoptotic factors in mice following exposure to acute irradiation after 7 days of simulated microgravity. The results demonstrated that significant reductions in spermatozoa, primary spermatocytes and spermatogonia, and increased globular cells in seminiferous tubule and pro-apoptotic proteins were observed in the group exposed to over 0.4 Gy irradiation. Collectively, the data suggest that lesions inflicted by simulated microgravity are not markedly modified by lower doses of irradiation (0.2 Gy) in mouse testis compared to the control group. However, testicular impairments were markedly evident in the group exposed to higher doses of carbon ions plus simulated microgravity, which may be due at least in part to elevated apoptosis initiated by the mitochondrial apoptosis pathway in germ cells.
分类： 核科学技术 >> 核材料与工艺技术 提交时间： 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要： We evaluated the protective effect of N-acetylcysteine (NAC) on immunity system irradiated by 12C6+ ion beam. Kun-Ming mice were whole-body irradiated by 12C6+ ion at doses of 0, 0.5, 1, 1.5, 2, 2.5 and 3 Gy. The results showed that in saline group, the lymphocytes DNA double-strand breaks (DSBs), maleic dialdehyde, thymocytes number in G0/G1 and apoptosis percentage increased with dose increment, and the levels of interferon-, glutathione, superoxide radical (SOD) and natural killer cells activity decreased with dose increment. However, there were no significant changes in NAC-treated group. The data indicated that pre-treatment with NAC could significantly remove the ROS by counteracting the glutamate, decrease excessive lipid peroxidation reaction and SOD damages, and protect DNA, lymphocytes and cytokines against irradiation.
分类： 地球科学 >> 地理学 提交时间： 2021-02-10 合作期刊: 《干旱区科学》
摘要： Crop residue is a major source of soil organic matter; therefore, application of crop straw to soil contributes to the sustainable development of organic agriculture. To better understand the transformation of crop straw in orchard soils, we investigated the relationship between the characteristics of straw decomposition and functional diversity of associated microbial communities in a long-term peach orchard, China. Mesh bags, each containing 30 g of corn or bean straw, were buried at a soil depth of 20 cm in a 12-year-old peach orchard for 360 d (October 2011–October 2012). Three treatments were applied, i.e., fresh corn straw, fresh corn straw with nitrogen fertilizer (urea, 10.34 g/kg), and fresh bean straw. Changes in straw residual rate, straw water content and soil conditions were monitored after treatment. The functional diversity of straw-associated microbial communities was analyzed by the Biolog-Eco microplate assay. During the decomposition process, straw residual rates did not vary considerably from 10 d (30.4%–45.4%) to 360 d (19.0%–30.3%). Irrespective of nitrogen addition, corn straw decomposed faster than bean straw. Corn straw with nitrogen fertilizer yielded the highest average well color development (AWCD) values (1.11–1.67), followed by corn straw (1.14–1.68) and bean straw (1.18–1.62). Although the AWCD values did not differ significantly among the three treatments, substantial differences occurred across various time periods of the decomposition process (P<0.01). In terms of carbon source utilization, the dominant microbial groups fed mainly on saccharides. Hard-to-decompose substances gradually accumulated in the middle and late stages of straw decomposition. Of the six categories of carbon sources tested, the utilization rate of aromatics was the lowest with corn straw, whereas that of polymers was the lowest with bean straw. Among different treatments, straw residual rate was negatively correlated to soil available phosphorous, soil available potassium and soil temperature (P<0.05), but not to soil water content. In some cases (corn straw with or without nitrogen fertilizer), straw residual rate was negatively correlated to straw water content, amino acid utilization and carboxylic acid utilization, and positively correlated with microbial species richness and evenness (P<0.05). Microbial community associated with corn and bean straw decomposition in soil was respectively dominated by aromatic- and polymer-metabolizing groups during the middle and late stages of this process, which could reduce the stability of microbial community structure and decrease the rate of straw decomposition in the fruit tree orchard.
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