分类: 核科学技术 >> 粒子加速器 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要: The macromolecular crystallography beamline BL17U1 at the Shanghai Synchrotron Radiation Facility (SSRF) is the first dedicated macromolecular crystallography (MX) beamline at a third-generation synchrotron in China. It utilizes an in-vacuum undulator as a source and is energy-tunable from 5 to 18 keV. The beamline was commissioned and opened for users in April 2009. The experimental station was upgraded in 2011 with an advanced detector, a high precision goniometer and an automatic sample exchanger for high efficient and high-throughput data collection of protein crystals. The current set-up allows for remote operation of sample mounting, centering and data collection of pre-frozen crystals. In recent two years, the number of PDB depositions from this beamline exceeds 330 each year. In this paper, we describe the complete BL17U1 beamline with upgraded end station and how it is managed for user community.
分类: 核科学技术 >> 粒子加速器 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要: CBCT scanners have been widely used in angiography, radiotherapy guidance, mammography and oral maxillofacial imaging. To cut detector size, reduce manufacturing costs and radiation dose while keeping a reasonable FOV, the flat panel detector can be placed off-center horizontally. This scanning configuration extends the FOV effectively. However, each projection is transversely truncated, bringing errors and artifacts in reconstruction. In this paper, a simple but practical method is proposed for this scanning geometry based on truncation compensation and the modified FDK algorithm. Numerical simulations with jaw phantom were conducted to evaluate the accuracy and practicability of the proposed method. A novel CBCT system for maxillofacial imaging is used for clinical test, which is equipped with an off-center small size flat panel detector. Results show that reconstruction accuracy is acceptable for clinical use, and the image quality appears sufficient for specific diagnostic requirements. It provides a novel solution for clinical CBCT system, in order to reduce radiation dose and manufacturing cost.