Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2022-04-07 Cooperative journals: 《计算机应用研究》
Abstract： In the Open Source Community, it’s essential to find and recommend suitable participants for newly initiated issues in order to solved the issues and develop the community. This paper proposed to construct a two-layer Graph Attention Network Participant Recommendation Model (GAT-UCG) based on the cooperative relationship records and the historical participated issues records of the developers. The method used to construct the model is obtaining the information of the problem participants and the interaction information of the developers first, and building the developer problem participation graph and the developer collaboration relationship graph respectively, then redistributing the weights to the edges through the attention mechanism, finally, figuring the Top-N recommendation of the problem participants according to the Issue node embedding representation obtained by the output layer. There are 7, 352 issues from popular Github repositories for experiments. The results showed that the GAT-UCG model outperforms the baseline method in three indicators: recommendation accuracy, recall, and F-Score.
Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-06-21 Cooperative journals: 《干旱区研究》
Abstract：干旱区湿地在改善地区生态环境，维护地区生态稳定等方面发挥着重要作用，研究干旱区湿地土壤碳（C）、氮（N）、磷（P）等元素的生态化学计量学特征，有助于深入了解干旱区湿地土壤养分的供给能力及循环与平衡机制。本文以河西走廊西段，疏勒河中下游的草本沼泽（T1）和季节性咸水沼泽（T2）土壤为研究对象，分析了这两种沼泽湿地土壤C、N、P生态化学计量学特征及其影响因素。结果表明：① 0～100 cm土壤C/N、N/P、C/P均为T2（15.07，5.94，98.01）＞T1（12.49，2.50，30.22）；随土层深度的增加，土壤C/N、N/P、C/P均在T1有两个峰值（0～10 cm和中间层），T2有一个峰值（中间层）。② 0～100 cm土壤C/N、N/P、C/P空间变异性大，且均为T2＞T1。③ T1和T2土壤的N/P与土壤水分呈极显著正相关（P<0.01），C/P与土壤水分、全N呈极显著正相关（P<0.01），与碱解N呈显著正相关（P<0.05）；T2土壤C/N、N/P、C/P与土壤容重呈极显著正相关（P<0.01），C/N与土壤水分呈极显著的正相关（P<0.01），N/P与土壤有机C呈显著正相关（P<0.05）；T1土壤N/P与土壤有机C呈极显著正相关（P<0.01）。④ 土壤水分是影响两种沼泽湿地土壤C、N、P计量比的关键因子。因此，保护干旱区湿地土壤关键在于采取合理的节水用水措施，该结果可为干旱区湿地土壤保护、管理以及生态恢复提供科学依据。
Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-06-19 Cooperative journals: 《干旱区研究》
Abstract：干旱区湿地在改善地区生态环境，维护地区生态稳定等方面发挥着重要作用，研究干旱区湿地土壤碳（C）、氮（N）、磷（P）等元素的生态化学计量学特征，有助于深入了解干旱区湿地土壤养分的供给能力及循环与平衡机制。本文以河西走廊西段，疏勒河中下游的草本沼泽（T1）和季节性咸水沼泽（T2）土壤为研究对象，分析了这两种沼泽湿地土壤C、N、P生态化学计量学特征及其影响因素。结果表明：① 0～100 cm土壤C/N、N/P、C/P均为T2（15.07，5.94，98.01）＞T1（12.49，2.50，30.22）；随土层深度的增加，土壤C/N、N/P、C/P均在T1有两个峰值（0～10 cm和中间层），T2有一个峰值（中间层）。② 0～100 cm土壤C/N、N/P、C/P空间变异性大，且均为T2＞T1。③ T1和T2土壤的N/P与土壤水分呈极显著正相关（P<0.01），C/P与土壤水分、全N呈极显著正相关（P<0.01），与碱解N呈显著正相关（P<0.05）；T2土壤C/N、N/P、C/P与土壤容重呈极显著正相关（P<0.01），C/N与土壤水分呈极显著的正相关（P<0.01），N/P与土壤有机C呈显著正相关（P<0.05）；T1土壤N/P与土壤有机C呈极显著正相关（P<0.01）。④ 土壤水分是影响两种沼泽湿地土壤C、N、P计量比的关键因子。因此，保护干旱区湿地土壤关键在于采取合理的节水用水措施，该结果可为干旱区湿地土壤保护、管理以及生态恢复提供科学依据。
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》
Abstract： Objective To detect miR-200a expression in human colorectal carcinnoma (CRC) cell lines and explore the role of miR-200a in regulating the biological behavior of CRC cells. Methods Real-time quantitative RT-PCR (qRT-PCR) was used to detect miR-200a expression levels in 6 CRC cell lines (HCT116, HT29, LS174T, SW480, SW620 and LoVo). miR-200a mimics were transiently transfected into LoVo, and the changes in cell proliferation, apoptosis, migration, and cell-cell adhesion were assessed using CCK-8 assay, TUNEL assay, transwell migration assay, and homogenous adhesion experiment, respectively. Results The expression of miR-200a was down-regulated in the 6 CRC cell lines, among which the highly metastatic LoVo cell line showed the lowest expression and the tumorigenic but non-metastatic CRC cell line HCT116 had the highest expression. Overexpression of miR-200a depressed cell proliferation and migration but promoted cell apoptosis and cell-cell adhesion in LoVo cells. Conclusion miR-200a plays a role in regulating the invasiveness and metastasis of CRC, and overexpression of miR-200a causes a significant reduction of cell proliferation and migration and promotes apoptosis and cell-cell adhesion in LoVo cells.
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