• 福建省科技期刊数字出版转型研究

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:科技期刊数字出版转型大势所趋,本文在对福建省科技期刊数字出版转型现状调查基础上,运用SWOT分析法,从优势(S)、劣势(W)、机会(O)、威胁(T)4个方面对福建省科技期刊数字出版转型的内部外部因素进行分析,并依据分析提出了完善法律法规,加强数字版权保护;加大政策扶持力度,营造良好的产业发展环境;整合产业链,探索经营模式;加强数字出版复合人才队伍的科技期刊数字出版转型等策略。

  • 涛副校长访谈:中共中央党校建设国家高端智库的实践与思考

    Subjects: Other Disciplines >> Synthetic discipline submitted time 2016-11-02 Cooperative journals: 《中国科学院院刊》

    Abstract: http://www.bulletin.cas.cn/ch/reader/view_abstract.aspx?file_no=20160809&flag=1

  • 基于离散泊松混合模型的教学评价数据建模

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2022-05-10 Cooperative journals: 《计算机应用研究》

    Abstract: Analyzing the evaluation data of students to teachers in the teaching evaluation system helps teachers understand the true attitudes of students to teachers, summarize teaching experience, improve subsequent teaching methods, and improve teaching quality. However, when evaluating teaching, random or malicious evaluations may occur among students, resulting in a large amount of noise in the evaluation data, which results in unsatisfactory feedback data. Therefore, this paper proposes a discrete Poisson mixture model to model the evaluation data of students with noise. Each discrete Poisson component in the mixture model corresponds to a class of students with similar evaluation modes. The model parameters in the loose distribution represent the evaluation scores in the corresponding evaluation mode. The log-likelihood function is constructed to measure the degree of fit between the mixed model and the evaluation data, and the gradient descent method is used to solve the model parameters with the highest degree of fit, to find the true evaluation of the students to the teacher, and to ensure the teacher-student relationship in the teaching evaluation system Communicate effectively. A large number of experimental results show that the model in this paper can quickly and accurately identify students with different evaluation modes from the evaluation data containing noise, and grasp the true evaluation of the students to teachers.

  • Analysis of genetic test results in 93 children with unexplained developmental delay/mental retardation

    submitted time 2022-08-23 Cooperative journals: 《中国全科医学》

    Abstract: Background Developmental delay (DD)/mental retardation (MR) has a complex etiology and a diverse and heterogeneous clinical presentation, making early and accurate diagnosis of these children very difficult.Few large samples in China have analysed the clinical data and genetic test results of this group of children to provide advice on definitive etiology and assessment of prognosis.Objective To analysis the results of genetic testing in developmental delay (DD)/mental retardation (MR) children of unknown origin, and to provide genetic counseling for genetic diagnosis, treatment planning and prognosis. Methods The clinical data of 93 children with suspected DD/MR of unknown etiology attending the rehabilitation department of Kunming Children's Hospital from September 2017 to September 2021 were collected, and whole-exome gene testing and copy number variation testing were performed to identify pathogenic mutation loci and copy number variants, and used Sanger sequencing to verify prior witness validation and analyze mutation situation. Results (1)93 children exhibited motor developmental backwardness, mental retardation or global developmental backwardness, and their developmental levels were behind normal developmental milestones. (2) Gene mutations were detected in 74 children, and the detection rate was 79.5%, of which 40 (43.1%) were pathogenic gene mutations, 13 (13.9%) children had gene copy number variants, and 21 children had mutations of unknown significance.(3) The diagnosis involved 50 genes, and the highest proportion of diseases caused by mutations in the SMN1 gene was spinal muscular atrophy (4/40), followed by Bethlem syndrome type 1 (3/40) caused by mutations in the COL6A2 gene and Joubert syndrome type 21 (2/40) caused by mutations in the CSPP1 gene. Conclusion Gene mutations and gene copy number variants are the main genetic causes of the development of DD/MR.WES combined with CNV can provide basis for the definitive diagnosis of DD/MR, especially for patients with non-specific clinical symptoms and phenotype

  • 近30 a甘肃省河东地区极端气温指数时空变化特征及趋势预测

    Subjects: Geosciences >> Geography submitted time 2020-06-02 Cooperative journals: 《干旱区地理》

    Abstract: 基于甘肃省河东地区61个气象站点1988-2017年逐日气温数据,利用Mann-Kendall检验,Sen's斜率估计方法分析甘肃省河东地区极端气温指数的时空变化趋势,并探讨极端气温指数与其影响因素之间的关系,最后利用NAR神经网络结合Hurst指数对甘肃省河东地区极端气温指数变化进行预测分析。数变化有密切关系,而太阳黑子等只与个别指数之间存在显著的相关性。(5)预测出的极端气温指数冷极值相对指数仍呈现下降趋势,冷极值的绝对指数、暖极值以及气温日较差、作物生长期仍然呈现增加趋势,但大多数指数与1988-2017年相比变化幅度有所降低。(6)与其他区域相比甘肃省河东地区大多数气温指数变化幅度处于中间水平,表现出其为多种不同气候区、自然区交界地带的特色。结果表明:(1)从时间上看,冷极值相对指数呈下降趋势,冷极值绝对指数、暖极值以及气温日较差、作物生长期呈上升趋势。(2)从空间上看,对冷极值变化反应最为敏感的是高寒湿润区,对暖极值变化反应最为敏感的是温带半湿润区和北亚热带湿润区,除北亚热带湿润区外各区域作物生长期的变化都达到了显著水平,而气温日较差仅在温带半湿润区达到了显著水平。(3)多数极端气温指数与经纬度、海拔之间有显著相关性,但受区域自然特点影响,经度与海拔对其影响实为一类。(4)亚洲区极涡强度、北半球极涡强度以及青藏高原指数B与极端气温指