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  • A multiphase direct aperture optimization for inverse planning in radiotherapy

    分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: Optimization of the inverse planning becomes critical because it follows the invention of intensity modulated radiotherapy (IMRT) to shorten the previous trial-and-error treatment process and increase efficiency. In this paper, the inverse planning is used to direct aperture optimization in the ARTS (Accurate/Advanced Radiotherapy System). The objective function was quadratic, both tolerance and dose-volume constraint types are supported. The memory efficient conjugate gradient algorithm is used to cope with its large data. Furthermore, to fully exploit the solution space, a shortest path sub-procedure is coupled into the whole algorithm, thus giving further possibility decreasing the objective function. Two clinical cases are tested, indicating that the applicability of this algorithm is promising to clinical usage.

  • Combination of artificial zeolite and microbial fertilizer to improve mining soils in an arid area of Inner Mongolia, China

    分类: 农、林、牧、渔 >> 土壤学 提交时间: 2023-10-17 合作期刊: 《干旱区科学》

    摘要: Restoration of mining soils is important to the vegetation and environment. This study aimed to explore the variations in soil nutrient contents, microbial abundance, and biomass under different gradients of substrate amendments in mining soils to select effective measures. Soil samples were collected from the Bayan Obo mining region in Inner Mongolia Autonomous Region, China. Contents of soil organic matter (SOM), available nitrogen (AN), available phosphorus (AP), available potassium (AK), microbial biomass carbon/microbial biomass nitrogen (MBC/MBN) ratio, biomass, and bacteria, fungi, and actinomycetes abundance were assessed in Agropyron cristatum L. Gaertn., Elymus dahuricus Turcz., and Medicago sativa L. soils with artificial zeolite (AZ) and microbial fertilizer (MF) applied at T0 (0 g/kg), T1 (5 g/kg), T2 (10 g/kg), and T3 (20 g/kg). Redundancy analysis (RDA) and technique for order preference by similarity to ideal solution (TOPSIS) were used to identify the main factors controlling the variation of biomass. Results showed that chemical indices and microbial content of restored soils were far greater than those of control. The application of AZ significantly increases SOM, AN, and AP by 20.27%, 23.61%, and 40.43%, respectively. AZ significantly increased bacteria, fungi, and actinomycetes abundance by 0.63, 3.12, and 1.93 times of control, respectively. RDA indicated that AN, MBC/MBN ratio, and SOM were dominant predictors for biomass across samples with AZ application, explaining 87.6% of the biomass variance. SOM, MBC/MBN ratio, and AK were dominant predictors with MF application, explaining 82.9% of the biomass variance. TOPSIS indicated that T2 was the best dosage and the three plant species could all be used to repair mining soils. AZ and MF application at T2 concentration in the mining soils with M. sativa was found to be the most appropriate measure.

  • Crystal Structures and Luminescent Properties of Three Coordination Polymers Based on 2,5-Furandicarboxylic Acid Ligand and 1,10-Phenanthroline

    分类: 化学 >> 物理化学 提交时间: 2017-11-05 合作期刊: 《结构化学》

    摘要: Three new coordination polymers, namely [Zn(FDA)(phen)(H2O)·H2O]n (1), [Cd(HFDA)(phen)2(NO3)] (2) and [Cd(FDA)(phen)]n (3) (H2FDA = 2,5-furandicarboxylic acid, phen = 1,10-phenanthroline) have been synthesized by the solvothermal method and characterized by elemental analysis, IR, powder X-ray diffraction, thermogravimetric analysis and X-ray single-crystal diffraction analysis. For 1, the neighboring Zn2+ ions are bridged by FDA2- as linkers to form one-dimensional (1D) chains, and phen ligands are as the terminal ligands. Furthermore, the 1D chains are packed into a three-dimensional (3D) supramolecular structure through hydrogen bonds and π-π interactions. For 2, the H2FDA ligand is partial deprotonation, which is a rare phenomenon among other coordination polymers based on H2FDA. Under the synergetic effect of phen ligands and the partial deprotonation of H2FDA, the structure of 2 is discrete. For 3, the Cd2+ ions are linked by two carboxylates of FDA2- ligand to give rise to 1D zig-zag chains, and phen ligands chelate the Cd2+ ions like 1. In addition, solid-state luminescent spectra of three coordination polymers were also studied at room temperature.

  • A method for direct conversion of EPID images to incident fluence for dose reconstruction

    分类: 核科学技术 >> 粒子加速器 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: A direct incident fluence measurement method based on amorphous silicon electronic portal imaging device (a-Si EPID) has been developed for pretreatment verification of intensity-modulated radiation therapy (IMRT). The EPID-based incident fluence conversion method deconvolves EPID images to the primary response distribution based on measured lateral scatter kernels in the EPID detector using Conjugate Gradient algorithm. The primary response is converted to the incident fluence based on measured fluence conversion matrix which corrects for off-axis position dependence of the a-Si EPID response and the horn beam profile caused by flatting filter. To verify feasibility and accuracy of this method, square fields of various sizes and two IMRT plans were delivered. The dose distributions computed based on EPID-derived incident fluence were compared with the measurement data. For all square field sizes except the smallest field (2 cm), the mean dose differences in cross-line dose profiles were within 1% excluding the penumbra region, and gamma passing percentages with a 2%/2 mm criterion were about 99%. For two IMRT plans, the least gamma passing percentage for all eight IMRT fields was 98.14% with 2%/3 mm criteria. It can be concluded that our direct EPID-based incident fluence conversion method is accurate and capable of being applied to pretreatment dose verification in clinical routines.

  • A hybrid voxel sampling method for constructing Rad-HUMAN phantom

    分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: An accurate and fast sampling method was developed on the modeling of a voxel phantom called Rad-HUMAN for radiation protection of MC-based radiation transport and simulation. The segmented organ voxels, which were assigned with three dimensional (3D) coordinates, were simplified through a two-step hybrid sampling algorithm. Firstly, certain voxels were sampled into a coordinate matrix by the nearest neighbor sampling. Secondly, the coordinate matrix was renewed using a weighted sampling. To compare visualization with the sampling, the resultant matrix was used to extract the contour of organs/tissues for constructing polygon-surface phantom. The feasibility and effectiveness of the sampling method was verified through the modeling of large organs (e.g. skeleton system) and application of transformation to MC computational geometries.