• Normalized Glandular Dose Coefficients for Digital Breast Tomosynthesis with the Chinese Detailed Breast Models

    分类: 核科学技术 >> 辐射防护技术 提交时间: 2023-11-20

    摘要: Objective: The increasing incidence of breast cancer among Chinese women has necessitated the utilization of breast X-ray screening, which carries radiation risk. This work aims to provide a dosimetry protocol for the Chinese female population, to replace the traditional standard that utilize simplified breast models, for the accurate estimation of patients mean glandular dose undergoing digital breast tomosynthesis (DBT).Approach: We have constructed the first set of Chinese female detailed breast models with their representative breast parameters. Considering the backscatter radiation and computational efficiency, we improved the combination of these models and the Chinese reference adult female whole-body voxel phantom. The image acquisition for four commercial DBT systems, which are widely employed in China, were simulated using the Monte Carlo method to obtain the normalized glandular dose coefficients of DBT (D_gN^DBT) and glandular depth dose (Dgdepz ) for different breast characteristics and X-ray spectra.Main results: We calculated a series of D_gN^DBT for breasts with different percentage mass glandularity (5%, 25%, 50%, 75%, and 100%) and compressed breast thicknesses (2cm, 3cm, 4cm, 5cm, 6cm, 7cm), at various tube potentials (25kV, 28kV, 30kV, 32kV, 35kV, and 49kV) and target/filter combinations (W/Rh, W/Al, Mo/Mo, Rh/Rh, Rh/Ag). The parameter dependence of breast characteristics and beam conditions on D_gN^DBT of detailed breast models were investigated. The D_gN^DBTresults were 14.6% - 51.0% lower than those of the traditional dosimetry standard in China. The difference inD_gN^DBT was mainly due to the decrease in the depth of the main energy deposition area caused by glandular distribution along the depth direction.Significance: The results obtained in this work could be employed for the improvement of breast dosimetry in China, and provide more detailed information about risk assessment undergoing DBT.

  • THUDosePD: a three-dimensional Monte Carlo platform for phantom dose assessment

    分类: 物理学 >> 核物理学 提交时间: 2023-10-23

    摘要: Monte Carlo simulations are frequently utilized in radiation dose assessments. However, many researchers find the prevailing computing platforms to be intricate. This highlights a pressing need for a specialized framework for phantom dose evaluation. To address this gap, we developed a user-friendly radiation dose assessment platform using the Monte Carlo toolkit, Geant4. The Tsinghua University Phantom Dose (THUDosePD) augments the flexibility of Monte Carlo simulations in dosimetric research. Originating from THUDose, a code with generic, functional, and application layers, THUDosePD focuses predominantly on anatomical phantom dose assessment. Additionally, it enables medical exposure simulation, intricate geometry creation, and supports both three-dimensional radiation dose analysis and phantom format transformations. The system operates on a multi-threaded parallel CPU architecture, with some modules enhanced for GPU parallel computing. Benchmark tests on the ICRP reference male illustrated the capabilities of THUDosePD in phantom dose assessment, covering the effective dose, three-dimensional dose distribution, and three-dimensional organ dose. We also conducted a voxelization conversion on the polygon mesh phantom, demonstrating the methods efficiency and consistency. Extended applications based on THUDosePD further underline its broad adaptability. This intuitive, three-dimensional platform stands out as a valuable tool for phantom radiation dosimetry research.

  • Study of a GPU-based parallel computing method for the Monte Carlo program

    分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: The Monte Carlo method can be widely applied to particle transport through numerous simulated data processing operations. However, this process consumes much time. Traditional parallel computing based on multi-CPU or multi-core CPU can effectively address this issue, but it is limited by inadequate computer hardware. Nonetheless, the current programmability and parallel processing capability of digital graphics processing units (GPUs) can sustain general computing applications such as Monte Carlo program simulation. This paper presents a method that facilitates the parallel computation of the Monte Carlo procedure through GPUs. Its feasibility is verified through a sample of simplified photon transport program, the results indicate that execution time can be shortened by approximately 90 times. Based on the general Monte Carlo program Geant4, the photon and electronic coupled transport module was examined, analyzed, and rewritten using the GPU programming language OpenCL to generate a Geant4 parallel tool [base on GPU parallel computing tool (BOGPT)]. The simulation results of the standard examples demonstrated that the outcomes of the BOGPT program are similar to those of Geant4 and the simulation time can be reduced by approximately three times. Finally, the GPU programming-based parallel computing method for Monte Carlo applications is accelerated and implementation prospects are broadened following further optimization.

  • Development of spectrum unfolding code for multi-sphere neutron spectrometer using genetic algorithms

    分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: In the process of neutron spectrum measurement using the multi-sphere neutron spectrometer, energy response functions and detector readings should be applied to neutron spectrum unfolding. Mathematically, there can be multiple solutions to this problem, but only one actual neutron spectrum exists. Compared with common numerical spectrum unfolding methods, genetic algorithms have the characteristics of global optimization and probabilistic search. Therefore, they are chosen to be the spectrum unfolding algorithms for the multi-sphere neutron spectrometer (MNS IL100) developed by Tsinghua University. Firstly, the detector and different size polyethylene spheres of MNS IL100 were modeled to calculate the energy response functions by applying Monte Carlo simulation. Then based on the physical and mathematical properties of the spectrum unfolding problem by using genetic algorithms, effective search space and proper fitness function were determined to improve the efficiency of search and iteration. The elitism replacement scheme was used to ensure convergence and the pseudo-parallel strategy was used to inhibit premature convergence. According to the algorithms mentioned above, a spectrum unfolding code was developed and tested with several typical neutron spectra. At last, MNS IL100 and the spectrum unfolding code were used in actual experiment of 252Cf neutron source spectrum measurement. The experimental result is in good agreement with the 252Cf standard neutron spectrum, verifying the effectiveness and practicality of using genetic algorithms to unfold the neutron spectrum with combination of several processing strategies.

  • High sensitivity ultraviolet graphene-metamaterial integrated electro-optic modulator enhanced by superlubricity

    分类: 光学 >> 量子光学 提交时间: 2023-02-19

    摘要: Ultraviolet (UV) electro-optic modulation system based on graphene-plasmonic metamaterials nanomechanical system (NEMS) with superlubricity is investigated. Due to the strong optical absorption intensity of graphene in the UV region and the combination of metamaterial structure based on surface plasmons, the modulation depth of the UV NEMS electro-optic modulator approaches as high as 8.5 times compared to the counterpart modulator in visible light region. Meanwhile, the superlubricity significantly reduces the power consumption of the UV electro-optic modulation system due to its extremely low friction coefficient. It also significantly improves the response speed of the modulator, which can reach the order of a nanosecond. The modulation voltage can be lower than 200 mV. The proposed electro-optic modulation system has a simple structure and high sensitivity, which is supposed to have important applications in UV optoelectronic devices and systems.