Subjects: Library Science，Information Science >> Information Science submitted time 2017-11-08 Cooperative journals: 《数据分析与知识发现》
Abstract：【目的】利用SEER 数据库, 找出对非小细胞肺癌患者预后生存的影响因素并预测患者预后生存状态, 指导肿瘤预后评价。【方法】采用单因素统计学方法及Logistic 回归分析初步筛选预后相关因素, 利用贝叶斯网络方法构建患者术后生存预测模型, 并与其他三种常见的机器学习分类算法所建模型效能做比较。【结果】最终纳入模型的预后变量共5 项, 包括年龄、肿瘤大小、组织学分级、肿瘤分期和受累淋巴结比率。贝叶斯网络所建模型对非小细胞肺癌患者生存状况预测准确率达到72.87%。【局限】SEER 数据库内纳入的预后因素有限, 一定程度影响预测效果。【结论】贝叶斯网络可探寻变量间的关系并构建肺癌患者最优预后模型, 辅助医生判断患者预后情况及治疗效果, 优于决策树、支持向量机及人工神经网络三种模式。
Subjects: Library Science，Information Science >> Information Science submitted time 2017-11-08 Cooperative journals: 《数据分析与知识发现》
Abstract：【目的】利用SEER 数据库, 找出对非小细胞肺癌患者预后生存的影响因素并预测患者预后生存状态, 指导肿瘤预后评价。【方法】采用单因素统计学方法及Logistic 回归分析初步筛选预后相关因素, 利用贝叶斯网络方法构建患者术后生存预测模型, 并与其他三种常见的机器学习分类算法所建模型效能做比较。【结果】最终纳入模型的预后变量共5 项, 包括年龄、肿瘤大小、组织学分级、肿瘤分期和受累淋巴结比率。贝叶斯网络所建模型对非小细胞肺癌患者生存状况预测准确率达到72.87%。【局限】SEER 数据库内纳入的预后因素有限, 一定程度影响预测效果。【结论】贝叶斯网络可探寻变量间的关系并构建肺癌患者最优预后模型, 辅助医生判断患者预后情况及治疗效果, 优于决策树、支持向量机及人工神经网络三种模式。
Subjects: Library Science，Information Science >> Information Science submitted time 2017-10-11 Cooperative journals: 《数据分析与知识发现》
Abstract： [Objective] This study developed a disease prediction model based on the support vector machine, using electronic medical records of the severe acute pancreatitis patients. [Methods] We first adjusted the kernel type and parameter values of the support vector machine method to get an optimized prediction model. Then, we combined it with univariable and multivariable logistic regression analysis methods to select features’ variable. Finally, we proposed a simplified early warning model for the severe acute pancreatitis. [Results] The new model’s prediction accuracy rate is 70.37%. Variables used by this model include: white blood cell count, serum calcium, serum lipase, systolic blood pressure, diastolic blood pressure and pleural effusion. [Limitations] Because of the small sample size, we only used this support vector machine method to develop the new disease prediction model. In the future, we will try to establish a larger examination system for the clinical trial. [Conclusions] Support vector machine can help us develop an optimal disease prediction model. A new system based on this model could support our clinical decision makings.
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