Synergy of Human Immunodeficiency Virus Protease Inhibitors with Chloroquine against Plasmodium falciparum In Vitro and Plasmodium chabaudi In Vivo

分类： 生物学 >> 生物医药 提交时间： 2017-05-10

Zhengxiang He Li Qin Lili Chen Nanzheng Peng Jianlan You Xiaoping Chen

摘要： The synergy of the activities between chloroquine and various human immunodeficiency virus protease inhibitors was investigated in chloroquine-resistant and -sensitive malaria parasites. In both in vitro and in vivo assay systems, ritonavir was found to be the most potent in potentiating the antimalarial action of chloroquine.

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