Subjects: Biology >> Bioengineering submitted time 2018-04-19 Cooperative journals: 《中国生物工程杂志》
Abstract：细菌脂蛋白是细胞膜的重要组成部分，对细菌发挥各种生理活性起重要作用，与营养摄取、环境感知、细胞膜和细胞壁稳态的维持、蛋白质的折叠和定位等过程密切相关。随着生物技术不断发展和完善，越来越多的脂蛋白种类及功能被发现。本文综述了革兰氏阳性菌中脂蛋白的功能、生物合成过程和应用方面的研究进展，重点介绍了脂蛋白生物合成过程中关键酶磷脂酰甘油转移酶（Lipoprotein diacylglyceryl transferase，Lgt）和脂蛋白信号肽酶（Lipoprotein signal peptidase II，LspA）对革兰氏阳性菌生理活性产生的影响，为今后革兰氏阳性菌脂蛋白的研究提出了展望和建议。
Subjects: Biology >> Bioengineering submitted time 2017-06-01 Cooperative journals: 《中国生物工程杂志》
Abstract： Lignocellulosic biomass, one of the most abundant resources in the world can be converted into value-added bio-chemicals by microbial fermentation. Compared with the traditionally used edible biomass materials, lignocelluloses fermentation by microorganism encounters the following key problems: developing economically efficient pretreatment of lignocellulose, increasing the microbial utilization of the second most abundant sugar xylose in lignocellulose hydrolysates, enhancing the microbial comprehensive utilization of mixed sugars and improving the microbial tolerance to inhibitors in lignocellulose hydrolysates, such as furfural and acetic acid. New breakthroughs have been made on the research of these problems recent years. In this review, the latest research advances were summarized to address these issues and prospects for future development of commercial microbial utilization of lignocellulose were suggested.
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