分类: 生物学 >> 生物物理学 >> 生物物理、生物化学与分子生物学 提交时间: 2016-05-12
摘要: The architecture and structural details of chromatin assembler, chromatin modifier, and chromatin remodeler, and their complexes with nucleosome and chromatin, are critical for revealing the molecular mechanisms for the establishment, maintenance and regulation of epigenetic information. The fast-developing cryo-electron microscopy (cryo-EM) provides an indispensible tool for the structure determiantion of the huge, multi-subunits, and flexible epigenetic regulation related macromolecular assemblies. In this review, we summarized the recent progresses on EM structural studies of macromolecules and complexes relating to epigenetic regulation.
分类: 物理学 >> 核物理学 提交时间: 2023-06-24
摘要: The multinucleon transfer (MNT) reaction is one promising way to produce neutron-rich heavy nuclei and even super heavynuclei and attracts more and more attentions theoretically and experimentally. A low energy nuclear structure spectrometer calledLENSHIAF specific to the MNT reactions will be designed and constructed in the ongoing big project HIAF in China. In theLENSHIAF spectrometer, the most challenge part is how to collect and stop efficiently the high-energy MNT products into the gascell. By using Monte-Carlo method, the geometry of the gas cell, the thickness of the titanium window/degrader, and the optimalgas pressure filled in the gas cell have been calculated and estimated. For neutron-rich nuclei around N=126 from 136Xe+198Ptreaction, with a titanium window/degrader with a thickness of 2.53.5 um, a cylindrical helium gas cell with a length of 0.6 m and adiameter of 1.2 m can satisfy the requirements to stop the target-like fragments. For heavier and super heavy nuclei from 238U+238Ureaction, with a 58 um thick titanium window/degrader, the cylindrical gas cell has to be as big as a length of at least 1.6 m and adiameter of 1.6 m.
分类: 地球科学 >> 地理学 提交时间: 2021-09-08 合作期刊: 《干旱区科学》
摘要: Plastic mulched ridge-furrow irrigation is a useful method to improve crop productivity and decrease salt accumulation in arid saline areas. However, inappropriate irrigation and fertilizer practices may result in ecological and environmental problems. In order to improve the resource use efficiency in these areas, we investigated the effects of different irrigation amounts (400 (I1), 300 (I2) and 200 (I3) mm) and nitrogen application rates (300 (F1) and 150 (F2) kg N/hm2) on water consumption, salt variation and resource use efficiency of spring maize (Zea mays L.) in the Hetao Irrigation District (HID) of Northwest China in 2017 and 2018. Result showed that soil water contents were 0.2%–8.9% and 13.9%–18.1% lower for I2 and I3 than for I1, respectively, but that was slightly higher for F2 than for F1. Soil salt contents were 7.8%–23.5% and 48.5%–48.9% lower for I2 than for I1 and I3, but that was 1.6%–5.5% higher for F1 than for F2. Less salt leaching at the early growth stage (from sowing to six-leaf stage) and higher salt accumulation at the peak growth stage (from six-leaf to tasseling stage and from grain-filling to maturity stage) resulted in a higher soil salt content for I3 than for I1 and I2. Grain yields for I1 and I2 were significantly higher than that for I3 and irrigation water use efficiency for I2 was 14.7%–34.0% higher than that for I1. Compared with F1, F2 increased the partial factor productivity (PFP) of nitrogen fertilizer by more than 80%. PFP was not significantly different between I1F2 and I2F2, but significantly higher than those of other treatments. Considering the goal of saving water and nitrogen resources, and ensuring food security, we recommended the combination of I2F2 to ensure the sustainable development of agriculture in the HID and other similar arid saline areas.
分类: 天文学 >> 天文学 提交时间: 2024-05-10 合作期刊: 《Research in Astronomy and Astrophysics》
摘要: We have developed a novel method for co-adding multiple under-sampled images that combines the iteratively reweighted least squares and divide-and-conquer algorithms. Our approach not only allows for the anti-aliasing of the images but also enables Point-Spread Function (PSF) deconvolution, resulting in enhanced restoration of extended sources, the highest peak signal-to-noise ratio, and reduced ringing artefacts. To test our method, we conducted numerical simulations that replicated observation runs of the China Space Station Telescope/ the VLT Survey Telescope (VST) and compared our results to those obtained using previous algorithms. The simulation showed that our method outperforms previous approaches in several ways, such as restoring the profile of extended sources and minimizing ringing artefacts. Additionally, because our method relies on the inherent advantages of least squares fitting, it is more versatile and does not depend on the local uniformity hypothesis for the PSF. However, the new method consumes much more computation than the other approaches.
分类: 物理学 >> 核物理学 提交时间: 2016-09-01
摘要: It is proposed to upgrade the endcap time-of-flight (ETOF) of the Beijing Spectrometer III (BESIII) with multi-gap resistive plate chamber (MRPC), aiming at overall time resolution about 80 ps. After the entire electronics system is ready, some experiments, such as heat radiating, irradiation hardness and large-current beam tests,are carried out to certify the electronics' reliability and stability. The on-detector test of the electronics is also performed with the beam at BEPCII E3 line, the test results indicate that the electronics system fulfills its design requirements.
分类: 核科学技术 >> 粒子加速器 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要: A test system is developed for the BESIII ETOF/MRPC beam tests of data acquisition, environment monitoring and automatic control. The software framework is based on the CAMAC bus, VME bus and Serial Port, which are responsible for communications with the detectors. The monitor system works well in the beam test.
分类: 物理学 >> 核物理学 提交时间: 2016-09-14
摘要: In order to improve the particle identification capability of the Beijing Spectrometer III (BESIII),t is proposed to upgrade the current endcap time-of-flight (ETOF) detector with multi-gap resistive plate chamber (MRPC) technology. Aiming at extending ETOF overall time resolution better than 100ps, the whole system including MRPC detectors, new-designed Front End Electronics (FEE), CLOCK module, fast control boards and time to digital modules (TDIG), was built up and operated online 3 months under the cosmic ray. The main purposes of cosmic ray test are checking the detectors' construction quality, testing the joint operation of all instruments and guaranteeing the performance of the system. The results imply MRPC time resolution better than 100ps, efficiency is about 98%燼nd the noise rate of strip is lower than 1Hz/(scm2) at normal threshold range, the details are discussed and analyzed specifically in this paper. The test indicates that the whole ETOF system would work well and satisfy the requirements of upgrade.