Subjects: Nursing >> Nursing submitted time 2023-12-22
Abstract： Objective To explore the application effect of multi-dimensional interactive teaching method Based on the concept of OBE (Outcome Based Education) in the cultivation of comprehensive quality and ability of clinical nursing undergraduates.Methods 70 undergraduate clinical nursing interns were divided into control grouPand observation group, 35 in each grouPaccording to random number table method. The control grouPreceived routine clinical teaching, and the observation grouPreceived multi-dimensional interactive teaching based on OBE concept. The implementation period of both groups was 1 month. After the implementation, the performance of the two groups' specialized theoretical knowledge and skills operation assessment was observed, and their comprehensive quality and ability of clinical nursing was assessed.Results After 1 month, the theoretical and technical performance of the observation grouPwas higher than that of the control grouP(P＜0.05). The evaluation of clinical nursing comprehensive quality and ability of nursing students was higher than that of control grouP(P＜0.05).Conclusion The multi-dimensional interactive teaching method based on the OBE concept can effectively stimulate the learning interest of nursing students, improve the mastery of specialized knowledge, and improve the comprehensive quality and ability of clinical nursing such as independent learning, clinical management ability, clinical nursing thinking, teamwork and nurse-patient communication, which can be promoted and applied in clinical teaching practice.
Peer Review Status:
Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-08-28
Abstract： Purpose : Exploring the mechanism and material basis of function of Sophora japonica in treating cirrhosis based on bioinformatics.
method : LC-MS acquired the ingredients of traditional Chinese medicine, using SuperPred and TTD databases to screen out the targets of action of Chinese medicine and disease respectively; Venny database was used for intersection analysis; A network diagram was constructed through Cytoscape software; Metoscape database was used for GO and KEGG enrichment analysis; CB-DOCK2 software completed molecular docking.
result : Through experimental screening, 85 ingredients and 46 intersection targets were found to have therapeutic effects on diseases. The core targets include HIF1A, TNF-a, PTGS2, MAPK1, etc. It is mainly related to cancer pathways, apoptosis, lipid, and atherosclerosis signal pathways for the treatment of cirrhosis by Sophora Tonkinensis Gagnep.
conclusion : Using bioinformatics methods to predict the mechanism of action and material basis of Sophora Tonkinensis Gagnep in treating cirrhosis, providing new ideas and clues for its further research.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-08-28
Abstract： Objective Research on the mechanism and substance basis of Eucommia Folium treating epilepsy based on bioinformatics technology. Methods Using LC-MS technology to obtain the components of Eucommiae Folium, and obtaining the components and disease targets through the SuperPred database and GeneCards database. Using Cytoscape software to establish network maps; Perform enrichment analysis using Metascape database; Use CB-dock software for molecular docking. Results A total of 113 active ingredients and 531 target points were screened from the Eucommiae Folium, with 29880 epilepsy disease target points, 57 intersection target points and nine core target points. The main related signaling pathways include cancer pathways, serotonin synapse, etc. Conclusions The mechanism of Eucommiae Folium in treating epilepsy may be related to inflammation response, providing a scientific theoretical basis for further pharmacological experiments.
Peer Review Status:Awaiting Review
Subjects: Nursing >> Nursing submitted time 2023-06-12
Abstract： To design an auricular acupoint probe with adjustable probe angle, in order to detect the positive points of special parts of auricle more accurately. The probe rod is composed of a hand-held handle, a connecting rod and a probe. The characteristics of the probe are as follows: a primary angle adjusting device is provided at the connection of the hand-held handle and the connecting rod, and a secondary angle adjusting device is provided at the connecting end of the connecting rod and the probe. The probe is convenient for the operator to fix the hole in the special part of the earlobe, and is more beneficial to the operator to save force. The probe is easy to operate and suitable for all kinds of patients. It has good clinical application prospect and is worth popularizing.
Peer Review Status:Awaiting Review
Subjects: Nursing >> Nursing submitted time 2023-06-12
Abstract： This article introduced a special auricular acupoint treatment tool bag. The tool bag is designed for effectively utilizing the space and placing various tools for auricular acupoint treatment. The special auricular acupoint treatment tool bag not only meets the operation needs, but also saves time and improves work efficiency, which is worthy of clinical application.
Peer Review Status:Awaiting Review
Subjects: Nursing >> Nursing submitted time 2023-01-17
Abstract：目的 总结1例轻度焦虑伴药物依赖失眠患者耳穴三序疗法临床疗效病例报告。方法 采用耳郭按摩、刮痧、耳穴贴压的耳穴三序疗法进行治疗，每周两次，分别周三、周日上午各一次，10次一个疗程，共治疗24次近两个半疗程。结果 耳穴三序疗法治疗后，PSQI量表评分由18分降为7分，SAS量表评分由58分降为26分，患者停药，焦虑及失眠痊愈，3个月后随访无复发。结论 通过耳穴三序疗法治疗能有效改善轻度焦虑伴药物依赖失眠患者的临床症状，可为临床治疗轻度焦虑及药物依赖失眠患者提供借鉴与参考。
Peer Review Status:Awaiting Review
Subjects: Nursing >> Nursing submitted time 2022-11-06
Abstract： After stroke, patients are prone to suffer hemiplegia, aphasia, insomnia, depression, constipation and other sequelae, reducing the quality of life of patients. As a traditional external treatment of Traditional Chinese Medicine, auricular acupuncture has the advantages of easy access to materials, easy operation, little pain, safety, effective and easy to accept, and has been gradually applied in the treatment of apoplexy sequelae. The paper summarized the related literature of auricular acupuncture therapy in the treatment of apoplexy sequelae in recent years, and summarized the origin, application and research of ear acupuncture, so as to provide reference for auricular acupuncture therapy in the treatment of apoplexy sequelae and provide a basis for auricular acupuncture therapy research.
Peer Review Status:Awaiting Review
Subjects: Nursing >> Nursing submitted time 2022-11-06
Abstract： Objective To investigate the effect of a three-step auricular acupoint therapy in the treatment of primary tinnitus. Methods The clinical data of 23 patients with primary tinnitus were retrospectively analyzed. Key issues in implementation of three-step auricular acupoint therapy and related nursing were summarized. Results The score of Tinnitus Evaluation Questionnaire(TEQ) was lower after treatment compared with that before treatment (P＜0.05). The score of Tinnitus Handicap Inventory(THI) dropped form (32.63±11.67) before treatment to(32.63±11.67) after treatment, with a significant difference(P＜0.05). The marked effective rate was 52.17%(12/23) after 2 courses of treatment. Conclusion The three-step auricular acupoint therapy, consisting of auricular massage, auricular scraping therapy, and auricular acupoint sticking and pressing therapy by syndrome differentiation, is an easy-to-operate and effective therapy for primary tinnitus. It is able to tonify liver and kidney, dredging collaterals and relieving the symptoms of tinnitus.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2022-07-26 Cooperative journals: 《中国全科医学》
Abstract： Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease, which poses a great threat to human health. The study found that compared with the healthy population, the composition and structure of lung and gut microbiota in patients with COPD changed significantly, that is, the microbiota was maladjusted. With the proposal of the concept of " lung-gut axis", the close relationship between lung and gut microbiota in human body has attracted more and more attention of researchers. Therefore, the research on lung and gut microbiota and their interaction plays an important guiding role in clarifying the occurrence and development mechanism of COPD. This paper reviews the composition characteristics and possible interaction mechanism of lung and gut microbiota in healthy people and patients with COPD, as well as the latest achievements in the prevention and treatment of COPD based on lung and gut microbiota and their interaction at this stage, in order to provide new ideas for the study of the pathogenesis of COPD and the early diagnosis, prevention and treatment of COPD.
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