Subjects: Biology >> Botany >> Applied botany submitted time 2021-04-13 Cooperative journals: 《广西植物》
Abstract： The pan-genome can represent all of the genetic diversities in a species or population, which is a limitation for obtaining only one single reference genome. The pan-genomics is becoming a new hot research area and being widely applicated in researches of many species in plants, animals and microorganisms, as the development of the whole genome sequencing and analysis technology. It provided powerful tools for resolving the genetic variation and polymorphism at levels of species or taxa, researches of functional genomics and reconstruction of phylogenetics, obtaining abundant of significant research achievements. However, present researches on pan-genomics still need improve due to several problems, e.g., extensive cost of whole genome sequencing and data analysis, inconsistent analysis standards, lack of deeper and comprehensive explanation of the obtained data, and difficulty of application of the research achievements. We summarized the research progresses of pan-genomes on exploitation of genetic diversity and functional genomics, including construction of a pan genome map, identification of genome variations and favorable genes, polymorphism of functional genes, population genetic diversity and systematic evolution, and discussed its potential in application of different research fields. Furthermore, we discussed the limitations existed in the present studies and possible solutions, and directed the development prospect in the future on pan-genomics.
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