分类: 天文学 >> 天文学 提交时间: 2023-02-19
摘要: The physics potential of detecting $^8$B solar neutrinos is exploited at the Jiangmen Underground Neutrino Observatory (JUNO), in a model independent manner by using three distinct channels of the charged-current (CC), neutral-current (NC) and elastic scattering (ES) interactions. Due to the largest-ever mass of $^{13}$C nuclei in the liquid-scintillator detectors and the potential low background level, $^8$B solar neutrinos would be observable in the CC and NC interactions on $^{13}$C for the first time. By virtue of optimized event selections and muon veto strategies, backgrounds from the accidental coincidence, muon-induced isotopes, and external backgrounds can be greatly suppressed. Excellent signal-to-background ratios can be achieved in the CC, NC and ES channels to guarantee the $^8$B solar neutrino observation. From the sensitivity studies performed in this work, we show that one can reach the precision levels of 5%, 8% and 20% for the $^8$B neutrino flux, $\sin^2\theta_{12}$, and $\Delta m^2_{21}$, respectively, using ten years of JUNO data. It would be unique and helpful to probe the details of both solar physics and neutrino physics. In addition, when combined with SNO, the world-best precision of 3% is expected for the $^8$B neutrino flux measurement.
分类: 光学 >> 量子光学 提交时间: 2023-02-19
摘要: Dense waveguide arrays with half-wavelength-pitch, low-crosstalk, broadband, and flexible routing capability are essential for integrated photonics. However, achieving such performance is challenging due to the relatively weaker confinement of dielectric waveguides and the increased interactions among densely packed waveguides. Here, leveraging the artificial gauge field mechanism, we demonstrate half-wavelength-pitched dense waveguide arrays, consisting of 64 waveguides, in silicon with -30dB crosstalk suppression from 1480nm to 1550nm. The waveguide array features negligible insertion loss for 90-degree bending. Our approach enables flexibly routing a large-scale dense waveguide array that significantly reduces on-chip estate, leading to a high-density photonic integrated circuit, and may open up opportunities for important device performance improvement, such as half-wavelength-pitch OPA and ultra-dense space-division multiplexing
分类: 医学、药学 >> 临床医学 提交时间: 2020-02-27
摘要: BackgroundThe COVID-19 cases increased very fast in the last two months. The mortality among critically ill patients, especially the elder ones, was relatively high. Considering that most of the dead patients were caused by severe inflammation response, it is very urgent to develop effective therapeutic agents and strategies for these patients. The human umbilical cord mesenchymal stem cells (hUCMSCs) have shown very good capability to modulate immune response and repair the injured tissue with good safety. Case PresentationHere, we reported the treatment process and clinical outcome of a 65-year-old female critically ill COVID-19 patient infected with 2019-nCoV (now called SARS-CoV-2). The significant clinical outcome and well tolerance was observed by the adoptive transfer of allogenic hUCMSCs.ConclusionsOur results suggested that the adoptive transfer therapy of hUCMSCs might be an ideal choice to be used or combined with other immune modulating agents to treat the critically ill COVID-19 patients.