Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2023-10-30 Cooperative journals: 《中国全科医学》
Abstract： Background The elderly are at high risk for acute pulmonary embolism（APE），and the difficulty of early identification and diagnosis of APE in the elderly has made the active search for an optimal prediction method for elderly patients with suspected APE a medical problem that must be faced. Objective To investigate the predictive value of the 4-level Clinical Pretest Probability Score（4PEPS）for pulmonary embolism（PE） in elderly patients with suspected APE. Methods Basic information and related clinical data were collected from elderly（age ≥ 60 years）hospitalized patients who completed spiral CT pulmonary arteriography（CTPA）examinations in the Third Affiliated Hospital of Zunyi Medical University from 2017 to 2021. The study subjects were divided into the APE group and non-APE group according to the CTPA criteria for the diagnosis of PE in 2018 Guidelines for the Diagnosis，Treatment and Prevention of Pulmonary Thromboembolism. The 4PEPS，Standard algorithm，AADD algorithm，YEARS algorithm and PEGeD algorithm were used to predict the APE of the study subjects，respectively，who were divided into the positive and negative groups，and the number of true positives， true negatives，false positives and false negatives of each prediction method was counted. The efficacy evaluation indexes of the five prediction method were calculated and their prediction values were compared. Results Among 1193 elderly hospitalized patients who completed CTPA examination，608（50.96%）were male and 585（49.04%）were female，with a median age of 74（68，81）years；323（27.07%）were APE patients and 870（72.93%）were non-APE patients; there was no statistically significant difference between elderly APE patients and elderly non-APE patients in terms of gender and age（P>0.05）. 4PEPS，AADD algorithm，Standard algorithm，YEARS algorithm and PEGeD algorithm for elderly patients with suspected APE had a sensitivity of 95.05%，97.83%，98.76%，97.21%，97.83%，the specificity of 31.84%，18.16%，12.87%，22.41%，22.41%，the correctness of 48.95%，39.73%，36.13%，42.67%，42.83%，Youden index of 0.27，0.16，0.12，0.20，0.20. The net reclassification improvement（NRI）of 4PEPS，Standard algorithm，YEARS algorithm and PEGeD algorithm compared to AADD algorithm were 0.218，-0.087，0.073，and 0.085，the difference of the NRI of 4PEPS compared to AADD algorithm was statistically significant（P<0.05）. Conclusion 4PEPS predicts elderly patients with suspected APE with high specificity，correctness，and Youden index，and the overall predictive value is significantly better than the remaining four methods，which may be the optimal prediction method for elderly patients with APE.
Subjects: Geosciences >> Other Disciplines of Geosciences submitted time 2019-09-10 Cooperative journals: 《干旱区研究》
Abstract：以伊宁市城区主干道旁表土层为研究对象，共采集52个土样，应用分光光度仪测定6种重金属（Hg，Cr，Ni，Pb，Cu和Zn）元素含量。基于地学统计法应用单项污染指数（CF）和污染负荷指数（PLI）研究道路重金属污染近况和解释环境质量问题。结果表明：① 表土层中Hg、Ni、Pb和Cu的均值各超出新疆土壤背景值的2.75、1.48、2.60倍和1.52倍，Cr和Zn均未超其背景值。除Pb以外，其余元素含量均未超过国家土壤环境质量Ⅰ级标准(mg·kg-1)。② 道路表土中6种元素均呈点和面状分布格局，各元素在研究区内均有高值，表明经济生产、工业发展、道路交通等人为活动对道路土壤生境具有消极影响。③ Hg、Pb表现为区域性严重污染，Ni和Cu均呈不同水平的轻度污染等级，Cr和Zn的轻微污染和无污染等级分别占17.31%、82.69%和23.08%、59.62%。④ 研究区各元素CF均值从大到小顺次为：Pb、Hg、Ni、Cu、Zn、Cr。重金属PLI平均值为1.20，表现为轻度污染。土壤中Pb较其他重金属污染严重。
Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2018-11-08 Cooperative journals: 《干旱区研究》
Abstract：利用天山地区26个气象站1961—2015年的逐月气温和降水资料，探讨不同气候基准态对气候监测和评估的影响，为天山地区气候变化研究提供更加科学客观的依据。研究表明:①天山东段是不同气候态下气温变化的敏感区，而天山北坡是年降水变化的敏感区。以Ⅳ态（1961—2015年）的变化为基准，在Ⅰ态（1961—1990年）与Ⅱ态（1971—2000年）下气温要素与降水要素的分析结果均偏高，Ⅲ态（1981—2010年）下分析结果则偏低。②以Ⅳ态的突变时间为基准,气温整体上Ⅰ态没有突变、Ⅱ态出现突变偏早，Ⅲ态出现突变偏迟。③Ⅰ态和Ⅱ态会使气温和降水等级偏小，而Ⅲ态会使气温和降水等级偏大。不同气候态对降水异常没有影响，Ⅲ态对气温异常产生的影响最小。④采用不同气候态分析天山地区同时段同类要素时，会出现正向变化也出现负向变化。同时在使用基准气候态进行气候变化分析时，需结合多因素对分析结果进行客观的评价。
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