Subjects: Library Science，Information Science >> Library Science submitted time 2023-08-27 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] Science and technology innovation is an important strategic support for modern economic system. After the reform and opening up, in order to promote China's economic development, China government introduced and implemented a series of science and technology policy aims to promote the development of science and technology. However, how is the founding effect of these science and technology and policies, how the changes in founding effects in the historical cycle of science and technology policy have caused wide spread concern.[Method/process] This paper conducted an empirical research of the National Science Fund for Distinguished Young Scholars Earth Science Project that has been in operation for 20 years(JieQing fund) as an example. In order to overcome the endogeneity problem caused by sample selection bias,the study used DID model to assess the effect of fund for distinguished young on the research papers output efficiency of scientists, and put forward the "environment-motivation-behavior" model to explain the research result.[Result/conclusion] The empirical results show that between 1994 to 2008, the significant funding effect of JieQing fund reached 12 years, with a significant proportion 80%. Scientists who have received JieQing fund(JieQing Scientists) were able to published more 0.412 to 3.234 papers per year than those who have not received JieQing fund. After data conversion,compared with other scientists who in the same period(Same period Scientists) of JieQing Scientists, JieQing scientists can published more 0.426-3.277 papers per year. The largest funded effect of JieQing fund was in 2002, but the funding effect was not significant in 2007 and 2008. When evaluating the effect of science and technology policy support, the control group can be constructed by this method in this paper to achieve the research purpose of causal effect inference.
Subjects: Library Science，Information Science >> Library Science submitted time 2023-07-26 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] The National Science Fund for Distinguished Young Scholars Project (JieQing Fund) has implemented more than 25 years, all the JieQing winners presented the growing trend of older in age, researcher's age funding for heterogeneity about JieQing implement performance has great meaning in managing the JieQing Fund in future.[Method/process] The object of the empirical in the paper was JieQing Fund from 1994 to 2018 in Earth Science. The research built three evaluation indexes which included scientific research paper output efficiency, innovation ability and academical influence. And put forward the "Input of human capital in science and technology-output of scientific research" model to explain the research results. The research used DID model to overcome the sample selective bias which may have bad influence in inner problems, at last, the study researched the heterogeneity in age when implement the JieQing Fund.[Result/conclusion] The results show that there is older trend of aging and 45 years old phenomenon among the scientists. The JieQing Fund has been in place for 20 years. The proportion of hypothesis supports that the older the subsidy age is, the better the subsidy effect is lower. Among the three evaluation indexes, the years with the largest funding effect and the age between 39 and 42 years accounted for the largest proportion in the 20 years of the implementation of the JieQing Fund. Therefore, no matter from all the JieQing Fund purpose, three evaluation indexes, JieQing Fund should avoid older tendency, expand funding for young excellent talents.
Subjects: Nursing >> Nursing submitted time 2022-10-21
Abstract： Objective To investigate the Beliefs about Medicines in patients with oral Rivaroxaban for the treatment of lower extremity deep venous thrombosis, and to provide evidence for improving the quality of anticoagulation. Methods A mixed-methods study using questionnaires and cognitive interview was conducted. Totally 144 patients with deep venous thrombosis of lower extremity treated with oral Rivaroxaban anticoagulant were evaluated by a self-designed general information questionnaire and Beliefs about Medicines Questionnaire-specific (BMQ-specific), and 25 of them were interviewed by a semi-structured in-depth interview. Results The scores of necessity belief and concern belief about oral Rivaroxaban anticoagulant were (15.14±3.92) and (12.60±3.12) respectively，and the score of BMQ-specific was(2.54±5.09). According to the interview data, four main themes were refined as follows: Experience of anticoagulant efficacy, lack of cognition of adverse drug reactions, concern about adherence to medication, lack of continuity of medical education. Conclusion On one hand, patients accepted the need for anticoagulant medication; On the other hand, they had concerns about the potential risk of bleeding and other adverse reactions, and hope to stop the drugs as soon as possible. The medical staff should timely identify the adverse cognition of patients, strengthen medication education, and improve the quality of anticoagulant drugs.
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》
Abstract： Objective To explore the clinical features, laboratory findings and treatment of infant leukemia. Methods A retrospective analysis of the clinical data was performed of the cases with the diagnosis of infant acute leukemia from August 1993 to October 2014 in our hospital. Results A total of 144 cases of infant leukemia were diagnosed in the defined period, including 83 cases of acute lymphoblastic leukemia, 55 myeloid leukemia, 1 hybrid acute leukaemia and 5 with incompatible cytological and immunophenotyping findings. The patients at the age of 9 to 12 months accounted for the largest proportion (38.2%), and 87.5% of the patients had hepatosplenomegaly; Six patients below 6 months old had skin infiltration. In about 1/3 of the patients, the white blood cells count was no greater than 100�09 /L. Ninety-five patients had chromosome examinations, which identified chromosome abnormalities in 67 patients, including 18 positive for t(4;11)or t(9;11)or t(11;19), and younger patients were more likely to have chromosome abnormalities. Thirty-seven patients underwent MLL gene detection and 11 of them had positive results; the positive patients had higher rate of chromosome 11 abnormalities than the negative patients. Most of the patients gave up treatments after diagnosis and only 6 patients older than 6 months completed regular chemotherapeutic treatments and were now in complete remission. Conclusion Infant leukemia is a rare type of leukemia with different clinical features from other types of leukemia. The patients often present with hepatosplenomegaly, high white blood cell counts, MLL gene fusion, and chromosome 11 abnormalities. The prognosis of infant leukemia is not favorable, and the current treatment still relies on chemotherapy.
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