Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-09-28
Song, Xiaochen
Zhang, Hui
Zhong, Sen
Tan, Xianjie
Ma, Shuiqing
Jin, Ying
Pan, Lingya
Wu, Ming
Cao, Dongyan
Yang, Jiaxin
Xiang, Yang
Abstract： Objective: The current treatment for early-stage neuroendocrine carcinoma of the cervix (NECC) mainly relies on radical hysterectomy and chemotherapy. The routine use of postoperative radiation is still in controversial. We want to evaluate the value of postoperative radiation in early-stage NECC.
Methods: A retrospective cohort study. Early-stage NECC patients from 2006 to 2022 in Peking Union Medical College Hospital were included. Depending on whether the patients received radiation therapy after surgery, they were divided into Postoperative non-radiation group (Group A) and Postoperative radiation group (Group B). We use Kaplan-Meier method to analyze the progression-free survival (PFS), overall survival (OS), recurrence and OS rate.
Results: Sixty-six cases were included, 32 (48.5%) in Group A and 34 (51.5%) in Group B. After 35 (range 12-116) months follow-up, 26 (39.4%) experienced recurrence. Compared with Group A, Group B had lower pelvic recurrence rate (12.5% vs 2.9%, p = 0.142), slightly higher distant recurrence rate (28.1% vs 44.1%, p = 0.177), and similar mortality rate (29.4% vs 31.3%, p = 0.871). Cervical stromal invasion ≥1/2 was more common in Group B (28.0% vs 63.0%, p = 0.012). Postoperative radiation in patients with cervical stromal invasion ≥1/2 showed an extended trend in PFS (33.9 months vs 47.9 months) and OS (40.7 months vs 70.0 months) but without statistical difference (p = 0.963, p = 0.636). Lymph-vascular space invasion (LVSI) is a high-risk factor for tumor recurrence (HR 9.13, p = 0.005), but radiation after surgery did not improve the PFS (51.5 months vs 48.8 months, p = 0.942) and OS (53.9 months vs 60.6 months, p = 0.715) in patients with LVSI.
Limitations: The limitations of this study are the retrospective nature and relative small sample size.
Conclusions: Postoperative radiation seems to prolong PFS and OS in patients with cervical stromal invasion ≥1/2. LVSI was a high-risk factor for tumor recurrence, but radiation after surgery in patients with LVSI seems have no survival benefits.
Peer Review Status:
Awaiting Review
Subjects: Library Science，Information Science >> Library Science submitted time 2023-08-27 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] This paper summarizes the selection criteria of the ACRL Excellence Award and the innovative service of the award-winning library in order to grasp the innovation and development trend of the international university libraries, then it provides enlightenment and references for the development of the innovation service of the university library in China. [Method/process] Using the combination of internet and literature research, this paper analyzes the library innovative services with ACRL excellence award from 2000 to 2017 as well as the typical cases of two libraries, and concludes the course of library innovation service development. [Result/conclusion] From the strategic planning of library services, new teaching activities, user feedback evaluation, institutional cooperation and employee career development, this paper puts forward some enlightenments and suggestions for China's university libraries.
Subjects: Library Science，Information Science >> Library Science submitted time 2023-08-27 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] Exploring innovative qualitative and quantitative methodology can provide reliable basis for selection and identification of key fields of science and technology in countries. Comprehensive view and analysis data can provide some reference to support decision-making of the key fields of science and technology in China.[Method/process] Firstly three select criteria of the key fields of science and technology were determined, which included research achievements, research input and science and technology planning. Then the comprehensive analysis of indicators and their weights were designed. The sum of the ranks for the above mentioned three criteria was calculated by extreme standardization method.[Result/conclusion]The top 10 key fields of science and technology in major countries of the world were selected and compared with each other and China. The conclusion can provide some reference for the key field layout of science and technology in China.
Subjects: Library Science，Information Science >> Information Science submitted time 2017-11-08 Cooperative journals: 《数据分析与知识发现》
Abstract：【目的】制定专题专利预警平台建设方案, 为长期的专题跟踪预警分析、专题数据再利用等工作提供一种解决途径。【方法】平台集成开源代码平台和工具(DSpace、OpenRefine、ECharts、VOSviewer 等), 实现对专题数据的存储、跟踪、分类、清洗、分析、管理等功能。【结果】选择极紫外光刻技术专题进行应用实践, 测试并解决实践过程中的细节问题, 验证专题专利预警平台的可行性和有效性。【局限】目前的专题专利预警平台数据处理全自动化、数据分析指标化、内容挖掘的关联实现等方面需要进一步优化。【结论】专题专利预警平台所实现的功能, 对于在技术研发生命周期内进行技术专利及时跟踪预警并分类管理有着现实的意义。
Subjects: Library Science，Information Science >> Library Science submitted time 2016-06-14
Abstract：【目的】通过梳理国际代表性数据期刊特点!更好地了解数据期刊发展的趋势和特征。 【方法】 选择15种数据期刊进行调研，对其发展现状、学科分布、出版方式、收录内容、引用机制、版权协议以及出版费用等方面进行了分析%。【结果】基于 Scientific Data、F1000 Reaseach、GigaScience 等代表性期刊的分析，成功的数据期刊特点包括科研人员的认知度、学术社群的认可度、知识产权保护以及管理透明化。【结论】中国数据期刊出版界在搭建数据知识库和数据期刊出版平台后，还需关注如何提升国际认知度和认可度，图书馆员除了为科研人员推荐这些开放获取的数据资源外，更重要的是协助他们鉴别良好的数据期刊，以保护他们的知识产权权益。
Peer Review Status:Awaiting Review
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