基于限制性立方样条模型从中医体质角度探讨大学生最佳睡眠时长

Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2022-07-09 Cooperative journals: 《中国全科医学》

马方晖 朱燕波 刘雯琼 吴新瑞 张千 赵心源 李玉琼 龙利群 陈皮皮

Abstract：

Background: Sleep duration is closely related to the health of college students. There is no conclusion on the optimal sleep duration of college students. And there is a lack of research on the dose-response relationship between sleep duration and TCM constitution. Objective: To explore the relationship between sleep duration and TCM Constitution of college students, so as to provide reference for Health education on sleep duration of college students. Methods: Purposive sampling combined with snowball sampling was used for on-site questionnaire survey, 1003 valid samples were obtained. The TCM Constitution of college students was evaluated by Constitution in Chinese Medicine Questionnaire of 41-item(CCMQ-41）, a self-designed questionnaire was used to measure sociodemographic information and lifestyle of college students. Taking sleep duration as independent variable and TCM Constitution scores as dependent variable, and control related confounding variables, the dose-response relationship between sleep duration and TCM constitution was analyzed by restrictive cubic spline fitting multiple linear regression model. Results: The sleep duration of college students with different gender, grade, eating habits and past history was different (P < 0.05). Multiple linear regression analysis showed that there was no linear relationship between sleep duration and TCM Constitution score. The dose-response relationship of the sample population showed that the sleep duration of the highest score of gentleness combined with the lowest score of biases (except specific diathesis) was about 8h, the sleep duration was > 8.5h, the score of gentleness showed a decreasing trend and the scores of qi deficiency and qi depression showed an increasing trend. The dose-response relationship of gender stratification showed that the sleep duration of men and women with the highest score of gentleness and the lowest score of biases (except specific diathesis) was about 8h, which was consistent with the results of the total sample. Conclusion: Considering all types of TCM status, the optimal daily sleep duration of college students is about 8 hours; College students should control the sleep duration no more than 8.5 hours to avoid increasing the possibility of the biases.

 Hits 1446  Downloads 167  Comment

断奶应激对幼龄反刍动物免疫系统的影响及其机理

Subjects: Biology >> Zoology submitted time 2017-10-10 Cooperative journals: 《动物营养学报》

张千 李发弟 李飞

Abstract：断奶初期，幼龄反刍动物的消化和免疫系统等尚未发育完全，断奶应激会导致幼畜体内激素水平及免疫功能改变，引起免疫系统抑制，诱发炎症反应，阻碍幼畜生长发育，增加患病风险。本文从糖皮质激素、免疫细胞、急性期蛋白和相关细胞因子4个方面阐述了断奶应激对幼龄反刍动物免疫系统的影响及其机理，旨在为相关研究提供科学依据。

 Hits 1803  Downloads 926  Comment