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  • Small angle X-ray scattering beamline at SSRF

    分类: 核科学技术 >> 粒子加速器 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: Beamline BL16B1 at Shanghai Synchrotron Radiation Facility (SSRF) is dedicated to small angle X-ray scattering (SAXS) study. It aims at probing microstructure and dynamic processes of polymers, nanomaterials, mesoporous materials, colloids, liquid crystals, metal materials, etc. At present, SAXS, wide angle X-ray scattering (WAXS), simultaneous SAXS/WAXS, grazing incident SAXS, and anomalous SAXS techniques are available. The sample-to-detector distance is adjustable from 0.2 m to 5 m. For conventional SAXS, the practicable q-range is from 0.033.6 nm-1 at incident X-ray of 10 keV. A continuous q-region of 0.0633 nm-1 can be achieved in simultaneous SAXS/WAXS mode. Time-resolved SAXS measurements in sub-second level can be performed. Detailed descriptions about status, performance and application of the SAXS beamline are given in this paper.

  • A multiphase direct aperture optimization for inverse planning in radiotherapy

    分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: Optimization of the inverse planning becomes critical because it follows the invention of intensity modulated radiotherapy (IMRT) to shorten the previous trial-and-error treatment process and increase efficiency. In this paper, the inverse planning is used to direct aperture optimization in the ARTS (Accurate/Advanced Radiotherapy System). The objective function was quadratic, both tolerance and dose-volume constraint types are supported. The memory efficient conjugate gradient algorithm is used to cope with its large data. Furthermore, to fully exploit the solution space, a shortest path sub-procedure is coupled into the whole algorithm, thus giving further possibility decreasing the objective function. Two clinical cases are tested, indicating that the applicability of this algorithm is promising to clinical usage.

  • GSN antibody pretreatment aggravates radiation-induced lung injury in mice

    分类: 核科学技术 >> 核材料与工艺技术 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》

    摘要: Radiation-induced lung injury is one of the main dose limiting factors for thoracic radiation therapy. Gelsolin (GSN) is a widespread, multifunctional regulator of cellular structure and metabolism. In this work, the roles of GSN in radiation-induced lung injury in Balb/c mice were studied. The GSN levels in plasma reduced progressively in 72 hours after irradiation, and then increased gradually. GSN contents in the bronchoalveolar lavage (BAL) fluid increased after thoracic irradiation, whereas mRNA levels of GSN in the lung tissue decreased significantly within 24 hours after irradiation and then increased again. Mice were intravenously injected with 50 g GSN antibody 0.5 hour before 20 Gy of thoracic irradiation. GSN antibody pretreatment increased lung inflammation, protein concentration in the BAL fluid and leukocytes infiltration in the irradiated mice. The activities of superoxidase dismutase (SOD) in the plasma and the BAL fluid in irradiated mice injected with GSN antibody were less than that of control groups, whereas the levels of malondialdehyde (MDA) increased. These results suggest that pretreatment of GSN antibody may aggravate radiation-induced pneumonitis.

  • Development of a large-scale remote sensing ecological index in arid areas and its application in the Aral Sea Basin

    分类: 地球科学 >> 地理学 提交时间: 2021-01-22 合作期刊: 《干旱区科学》

    摘要: The Aral Sea Basin in Central Asia is an important geographical environment unit in the center of Eurasia. It is of great significance to the ecological protection and sustainable development of Central Asia to carry out dynamic monitoring and effective evaluation of the eco-environmental quality of the Aral Sea Basin. In this study, the arid remote sensing ecological index (ARSEI) for large-scale arid areas was developed, which coupled the information of the greenness index, the salinity index, the humidity index, the heat index, and the land degradation index of arid areas. The ARSEI was used to monitor and evaluate the eco-environmental quality of the Aral Sea Basin from 2000 to 2019. The results show that the greenness index, the humidity index and the land degradation index had a positive impact on the quality of the ecological environment in the Aral Sea Basin, while the salinity index and the heat index exerted a negative impact on the quality of the ecological environment. The eco-environmental quality of the Aral Sea Basin demonstrated a trend of initial improvement, followed by deterioration, and finally further improvement. The spatial variation of these changes was significant. From 2000 to 2019, grassland and wasteland (saline alkali land and sandy land) in the central and western parts of the basin had the worst ecological environment quality. The areas with poor ecological environment quality are mainly distributed in rivers, wetlands, and cultivated land around lakes. During the period from 2000 to 2019, except for the surrounding areas of the Aral Sea, the ecological environment quality in other areas of the Aral Sea Basin has been improved in general. The correlation coefficients between the change in the eco-environmental quality and the heat index and between the change in the eco-environmental quality and the humidity index were –0.593 and 0.524, respectively. Climate conditions and human activities have led to different combinations of heat and humidity changes in the eco-environmental quality of the Aral Sea Basin. However, human activities had a greater impact. The ARSEI can quantitatively and intuitively reflect the scale and causes of large-scale and long-time period changes of the eco-environmental quality in arid areas; it is very suitable for the study of the eco-environmental quality in arid areas.

  • Coupling analysis of social-economic water consumption and its effects on the arid environments in Xinjiang of China based on the water and ecological footprints

    分类: 生物学 >> 植物学 >> 应用植物学 提交时间: 2020-05-31 合作期刊: 《干旱区科学》

    摘要: In arid areas, ecological degradation aroused by over-exploitation of fresh water, expansion of artificial oasis and shrinkage of natural oasis, has drawn attention of many scholars and officials. The water and ecological footprints can be used to quantitatively evaluate the water consumption of social-economic activities and their influence on the eco-environments. In addition, increase of the water footprint indicates the expansion of artificial oasis, and the influence on the natural oasis could be reflected by the variation of the ecological footprint. This study was conducted to answer a scientific question that what is the quantitative relationship between the expansion of the artificial oasis and the degradation of the natural oasis in the arid environments of Xinjiang, China. Thus, based on the social-economic data, water consumption data and meteorological data during 2001–2015, we calculated the water and ecological footprints to express the human-related pressure exerted on the water resources and arid environments in Xinjiang (including 14 prefectures and cities), and explore the relationship between the water and ecological footprints and its mechanism by using the coupling analysis and Granger causality test. The results show that both the water and ecological footprints of Xinjiang increased significantly during 2001–2015, and the increasing rate of the ecological footprint was much faster than that of the water footprint. The coupling degree between the water and ecological footprints was relatively high at the temporal scale and varied at the spatial scale. Among the 14 prefectures and cities examined in Xinjiang, the greater social-economic development (such as in Karamay and Urumqi) was associated with the lower coupling degree between the two footprints. Increases in the water footprint will cause the ecological footprint to increase, such that a 1-unit increase in the consumption of water resources would lead to 2–3 units of ecological degradation. The quantitative relationship between the increases of the water and ecological footprints, together with the intensities of water consumption both in the natural and artificial oases of Tarim River Basin, have approved the fact that the formation and expansion of 1 unit of the artificial oasis would bring about the degradation of 2 units of the natural oasis. These conclusions not only provide a technical basis for sustainable development in Xinjiang, but also offer a theoretical guide and scientific information that could be used in similar arid areas around the world.

  • Coupling analysis of social-economic water consumption and its effects on the arid environments in Xinjiang of China based on the water and ecological footprints

    分类: 环境科学技术及资源科学技术 >> 环境科学技术基础学科 提交时间: 2020-04-23 合作期刊: 《干旱区科学》

    摘要: In arid areas, ecological degradation aroused by over-exploitation of fresh water, expansion of artificial oasis and shrinkage of natural oasis, has drawn attention of many scholars and officials. The water and ecological footprints can be used to quantitatively evaluate the water consumption of social-economic activities and their influence on the eco-environments. In addition, increase of the water footprint indicates the expansion of artificial oasis, and the influence on the natural oasis could be reflected by the variation of the ecological footprint. This study was conducted to answer a scientific question that what is the quantitative relationship between the expansion of the artificial oasis and the degradation of the natural oasis in the arid environments of Xinjiang, China. Thus, based on the social-economic data, water consumption data and meteorological data during 2001–2015, we calculated the water and ecological footprints to express the human-related pressure exerted on the water resources and arid environments in Xinjiang (including 14 prefectures and cities), and explore the relationship between the water and ecological footprints and its mechanism by using the coupling analysis and Granger causality test. The results show that both the water and ecological footprints of Xinjiang increased significantly during 2001–2015, and the increasing rate of the ecological footprint was much faster than that of the water footprint. The coupling degree between the water and ecological footprints was relatively high at the temporal scale and varied at the spatial scale. Among the 14 prefectures and cities examined in Xinjiang, the greater social-economic development (such as in Karamay and Urumqi) was associated with the lower coupling degree between the two footprints. Increases in the water footprint will cause the ecological footprint to increase, such that a 1-unit increase in the consumption of water resources would lead to 2–3 units of ecological degradation. The quantitative relationship between the increases of the water and ecological footprints, together with the intensities of water consumption both in the natural and artificial oases of Tarim River Basin, have approved the fact that the formation and expansion of 1 unit of the artificial oasis would bring about the degradation of 2 units of the natural oasis. These conclusions not only provide a technical basis for sustainable development in Xinjiang, but also offer a theoretical guide and scientific information that could be used in similar arid areas around the world.