Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》
Abstract：伴随着媒体融合的发展,新闻出版行业在资金扶持、政策导向等推动下,获得了进一步发展。同时,国内也进行了许多关于融媒体时代下期刊发展的研究,但通过关键词检索能够发现,当前更多研究目光放在了记者群体的转变路径方面,关于编辑群体的转型研究较为缺乏,特别是科技期刊编辑。鉴于此,文章以融媒体时代为视角,重点探索了科技期刊编辑的转型路径,旨在丰富该领域研究。
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2022-09-06 Cooperative journals: 《中国全科医学》
Abstract： Background Breast cancer is the leading cause of death among women worldwide, with a high incidence and heavy disease burden. Objective To assess the prevalence of breast cancer incidence and mortality in Chinese women from 1990 to 2019. Methods Extract the 2019 Global Burden of Disease Study database to estimate the age effect, period effect, and cohort effect in the risk of breast cancer incidence and mortality among Chinese women from 1990 to 2019, the age-period-cohort Bayesian model was used to fit the trend of breast cancer incidence and mortality in Chinese women from 1990 to 2019. Results The crude incidence of breast cancer among Chinese women increased from 14.14/100,000 to 52.81/100,000, and the crude death rate increased from 7.22/100,000 to 13.40/100,000 during 1990—2019. The standardized incidence of breast cancer showed an increasing trend in general (17.07/100,000 in 1990, 35.61/100,000 in 2019), while the standardized mortality was stable (9.16/100,000 in 1990, 8.98/100,000 in 2019). The results of the age-period-cohort model showed that the net drift value of breast cancer incidence in women of all age groups was 2.58% (95%CI: 2.34%~2.83%), and the local drift value reached the highest value in the 65~69 years old group (3.46%, 95%CI: 3.11%~3.80%). The net drift value of mortality was -0.75% (95%CI: -1.09%~-0.41%), the local drift value was stable at 15~45 years old, and the local drift value was more than 0 after about 60 years old. The risk of breast cancer incidence and mortality increased with age. Compared to those during the period of 2000—2004, the period effect of incidence risk showed an increasing trend (RR:0.79~1.47), while the period effect of mortality risk showed a decreasing trend (RR:1.08~0.90). Setting the cohort of 1955—1959 as the control group, the cohort effect of breast cancer incidence risk increased (RR: 0.27~2.48), and the cohort effect of breast cancer mortality risk increased firstly and decreased after then (RR:0.78~1.06~0.44). Conclusion The incidence and mortality of breast cancer in Chinese women increased continuously from 1990 to 2019, and breast cancer incidence and mortality risk was dominantly influenced by age effect and cohort effect.
Subjects: Psychology >> Cognitive Psychology Subjects: Psychology >> Physiological Psychology submitted time 2021-09-10
Abstract： " Working memory training (WMT) has induced neuroplasticity, but its specific mechanism remains unclear. In order to explore the spatio-temporal characteristics of brain function changes induced by WMT in normal population, the findings of 37 fMRI studies on WMT in normal population over the last 20 years were summarized with a step-by-step approach and two assumptions based on two theories, Extended Parieto-Frontal Integration Theory(ExtPFIT) and neuro efficiency hypothesis. First, the changes in activation pattern and function connectivity of the various brain regions before and after WMT were compared using descriptive review, frequency analysis and Chi-square test. It showed that there were 5 networks, 7 macroscopic areas and 3 sub-regions in brain involved in WMT. Especially, the activation in 3 respective sub-regions of superior frontal gyrus, inferior parietal lobule and cingulate gyrus was weakened more than their activation enhanced, and this difference was statistically significant. Then, 26 studies among them were used to conduct meta-analysis with activation likelihood estimation method, and it showed that 3 sub-regions with the statistically significant effect were middle frontal gyrus (BA6 and 8), superior frontal gyrus (BA6) and anterior cingulate gyrus (BA24 and 32). Next, based on the comprehensive results of qualitative and quantitative research analysis, a spatio-temporal model of decreased distribution in brain regions was proposed, and 5 results and their discussion were obtained with the said model. In addition, 33 studies among them were analyzed using non-parametric tests to check the factors that possibly regulated the training effect of WMT, which showed that the task type and time of WMT had statistically significant effects on brain activation. According to the above analysis, four conclusions were drawn regarding the neuroplasticity induced by WMT in normal population, i.e. 1) WMT could either weaken or enhance the brain activities, and the weakening effect appeared to be more prominent; 2) such changes occurred mostly in the frontal-parietal network, but also in the temporal network, occipital network, cingulate gyrus, striatum and other network, which reflected the whole-brain functional connectivity within a certain range. In addition, updating and shorter time of WMT tended to induce more weakening effects; 3) 3 sub-regions of the middle frontal gyrus, superior frontal gyrus and anterior cingulate gyrus highlighted the spatial characteristics, and the other three sub-regions of superior frontal gyrus, inferior parietal lobule and cingulate gyrus mainly reflected the temporal characteristics of neuroplasticity induced by WMT; 4) ExtPFIT and neural efficiency hypothesis respectively supported the spatial-temporal characteristics of neuroplasticity induced by WMT. Finally, it was proposed that future further research of neuroplasticity induced by WMT need to distinguish the training effect reflected in 3 sub-regions of superior frontal gyrus, inferior parietal lobule and cingulate gyrus, and to explore the comprehensive influencing factors that increase or decrease the acitivation of brains induced by WMT.
Peer Review Status:
Awaiting Review
Subjects: Biology >> Bioengineering submitted time 2017-07-24 Cooperative journals: 《中国生物工程杂志》
Abstract： Construction of human SP-B protein transgenic mice and bacterial pneumonia model
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