Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc. submitted time 2022-11-16 Cooperative journals: 《中国全科医学》
Abstract：
Background Frailty is common in cancer patients, which seriously affects the prognosis of patients. Objective To identify the factors associated with frailty in cancer patients by meta-analysis, and to provide scientific basis for the design and implementation of frailty intervention program of frailty in cancer patients. Methods The databases of China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Journal Database (VIP), Wanfang, PubMed, Web of Science, Cochrane Library, CINAHL and Embase were searched to collect the studies on the associated factors of frailty in cancer patients from the inception to August 2022. A meta-analysis on the included literature was performed by using Stata 17.0 and RevMan 5.4. Results A total of 11 articles were included, including 9 cross-sectional studies and 2 cohort studies, including 2898 cancer patients, including 1025 frailty patients, involving 12 associated factors. The results of meta-analysis showed that the average incidence of frailty in cancer patients was 34%, and the associated factors were age [OR=1.16, 95%CI (1.05, 1.27), P<0.001], educational level [OR=0.78, 95%CI (0.68, 0.90)], comorbidity [OR=1.46, 95%CI (1.28, 1.67), P<0.001], body mass index (BMI) [OR=1.13, 95%CI (1.05, 1.21), P<0.001], albumin [OR=0.33, 95%CI (0.12, 0.90), P=0.03], nutritional status [OR=2.77, 95%CI (1.27, 6.06), P=0.01], syndrome group [OR=1.07，95%CI（1.04，1.09），P<0.001]，depression [OR=1.27, 95%CI (1.12, 1.44), P<0.001], instrumental activities of daily life (IADL) [OR=0.50, 95%CI (0.42, 0.59), P<0.001), while gender [OR=0.81, 95%CI (0.54, 1.21), P=0.30], marital status [OR=0.21, 95%CI (0.02, 2.31), P=0.20] and hemoglobin [OR=0.51, 95%CI (0.22, 1.22), P=0.13] was not related to the frailty of cancer patients. Conclusion The available research evidence suggests that age, education level, comorbidity, BMI, albumin, nutritional status, syndrome group, depression and IADL are the associated factors of frailty in cancer patients. Cancer patients with advanced age, low education level, combined with other diseases, High BMI, albumin level < 35 g/L, poor nutritional status, with symptoms group, depression and low activities of daily living are the priority population we need to pay attention to.
Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2022-10-13 Cooperative journals: 《中国全科医学》
Abstract： BackgroundWith the growing problem of obesity, the demand for bariatric surgery has increased these years. Patients still need to maintain good living habits after surgery to consolidate the weight loss effects.While the behavioral guidelines are relatively mature, patient’s behavioral compliance is not ideal, resulting in a higher rate of re-obesity postoperative. We can depend onstrategies to promote dietary and physical activity behaviors in patients from theperspective of cognitive factors.ObjectiveSystematic coding of dietary and physical activity behavior promotion strategies after bariatric surgery from the perspective of cognitive factors.Methods The Whittemore&Knafl integrative review method was used. The database of PubMed、Web of Science、Cochrane、CINAHL、CNKI and Wanfang Data were searched for studies related to diet and physical activity behavior promotion strategies after bariatric surgery from January 1994 to June 2022.The 2016 version of the Critical Appraisal Skills Program (CASP) was used to evaluate the quality of the literatures.Studies met the inclusion criteria were included, and the strategies were uniformly coded and merged according to CALO-RE taxonomy.Results A total of 25 studies were included, including 17 randomized controlled trials, 4 observational studies, and 4 reviews.After coding, all strategies were covered by CALO-REtaxonomy, involving 25kinds of strategies, mainly including behavior monitoring, social support, goal setting, obstacle recognition, etc.A total of 46 strategies were obtained in the “behavioral promotion strategies of diet and physical activity after bariatric surgery”.ConclusionsThrough the application of the integrative review method and the guidance of CALO-REtaxonomy, a systematic, comprehensive and standardized integration of dietary and physical activity behavior promotion strategies from the perspective of cognitive factors was achieved for post-bariatric patients.This study provided a technical reserve for behavior management after bariatric surgery, and are expected to further improve patients’ dietary and physical activity behavior status, thereby consolidating the effect sof bariatric surgery.
Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc. submitted time 2017-03-23
Abstract：摘要： 目的 介绍“中国彩巢计划：成长在中国（Chinese Color Nest Project – CCNP: Growing Up in China 2013-2022）”大型学龄儿童青少年脑与行为生长曲线项目。 方法 在全国范围内分期分步地开展毕生发展各年龄段的心理行为与脑影像样本积累，未来十年 CCNP 将基于加速纵向实验设计方法，建立中国人脑毕生发展的常模轨线。 结果 作为“彩巢”计划的脑发育项目，devCCNP 已经完成对重庆北碚区 192 名健康儿童青少年（6-18 岁）的 5 年追踪。 结论 devCCNP就实验设计、样本采集策略、数据获取和存储、初步结果和数据共享等方面都说明本计划具备长期实施的可行性。
Peer Review Status:
Awaiting Review
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