Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》
Abstract：元宇宙是最近十分火热的复杂概念，不仅关涉技术突破与资本利益，更需要反思其中深层的文化问题。本文从元宇宙带来的场景化体验出发，探讨元宇宙的真实性与内在迷幻性、文艺的光晕与版权问题，信息民主化的同时又对想象和思考产生影响，能否达到理想形态下诗意的栖居，是在场还是缺席?是赋权还是制约?而无论何种技术的演进都应该聚焦于人的全面发展与促进社会整合。
Subjects: Psychology >> Developmental Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》
Abstract： Many empirical evidences provide sufficient support on the assumption that multicultural experience fosters creativity. The effect could be observed only in the individuals who engaged in two inconsistent cultures deeply. Moreover, the cognitive skills which include alternation, integration and inclusion developed by dual-identity individuals, foster their creativity. Future researches could be directed to strengthen its external validity in diverse samples, explore the mediating role of other variables such as stress appraisal, approach motivation, positive emotions, and expand domestic research on this topic.
Subjects: Psychology >> Developmental Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》
Abstract： The search for meaning in life refers to the motivation and effort in understanding one’s own life, finding or establishing life purpose, or accomplishing life significance. Unfortunately, consensus is still lacking on its cause. Deficit correcting hypothesis holds that, meaning search primarily originates from its absence or deficit, and once meaning restored, the search would decay. As opposed, Life affirming hypothesis maintains that, meaning search stems from the motivation to consolidate and strengthen life experience, and therefore the effort is always incessant. This article discusses the evidence, deficiencies and applicable situations of above two perspectives, and on this base proposes an "antecedent factor model" to account for the determinants of search for meaning in life. This model hypothesizes meaning need as the premise of meaning search, and believe the motive to search for meaning would arise as long as the current "meaning level" is perceived to be lower or higher than the original state. Future research should develop multidimensional meaning search scales, strengthen experimental research, and explore factors that influence meaning search judgment.
Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2018-06-19 Cooperative journals: 《计算机应用研究》
Abstract： Aiming at the problem that it is difficult for the traditional fault diagnosis method to extract effective features from QAR data, this paper proposed a dual-channel fusion model, CNN-LSTM, which combines the Convolutional Neural Network(CNN) and the Long Short-Term Memory(LSTM) . Respectively as two channels, CNN and LSTM fused through the attention mechanism to make the model able to simultaneously express the features of the data in both space dimension and time dimension and verified the validity of the feature extraction of the fusion model through time series prediction. Results of the experiment show that when compared with single CNN or LSTM, the dual-channel fusion model can extract data features more effectively, make the errors of both single-step prediction and multi-step prediction reduce by an average of 35.3%, and provide a new research idea for fault diagnosis based on QAR data.
Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2018-04-12 Cooperative journals: 《计算机应用研究》
Abstract： On the basis of compressed sensing(CS) , this paper proposed an improved FOCUSS algorithm for the reconstruction of electrical capacitance tomography (ECT) , which aiming at the ill-conditionedness and ill-posedness of the inverse problem of ECT. The discrete cosine transform (DCT) basis made the grayscale signals of original images sparse. In the process of solving the inverse problem by employing the regularized FOCUSS algorithm, it introduced the quasi-Newton method to approximate and solve the intermediate sparse variables to improve the accuracy of signal reconstruction. Results of the simulation show that compared with LBP, Tikhonov, Landweber and FOCUSS algorithm, the improved FOCUSS algorithm can effectively distinguish the different media in the substance field, alleviate the over-smoothing effect, reduce the image error between the original image and the reconstructed image to 0.23, increase the correlation coefficient to 0.80, offer better image quality, and provide a new idea for the research on the algorithm for the reconstruction of ECT.
Subjects: Biology >> Bioengineering submitted time 2017-12-13 Cooperative journals: 《中国生物工程杂志》
Abstract：在医学上，神经系统对神经损伤的自我修复能力往往有限。[摘要第一句话已根据修改意见删除]因此，探索有效修复损伤神经的方法已经成为近年来研究热点。研究发现脂肪干细胞对各类损伤神经都有一定的修复作用，可作为修复神经损伤的种子细胞。脂肪干细胞不仅具有干细胞的特性而且还具有自身的优点，首先它属于成体细胞，来源于中胚层，具有多种分化的潜能，其次免疫原性较低，易于取材，另外脂肪干细胞移植后的风险较低，因此被认为是修复神经损伤的优秀种子细胞。本文就脂肪干细胞的特性以及脂肪干细胞在神经创伤修复方面的研究进展和存在的问题进行综述。
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》
Abstract： Objective To investigate the protective effect of ulinastatin (UTI) against acute lung injury induced by heatstroke in mice. Methods Sixty C57/BL6 mice were randomly divided into 6 groups, with 10 mice in each: control group, heatstroke group, UTI pretreatment group, saline pretreatment group, UTI post-treatment group, saline post-treatment group. The control mice were housed at a controlled room temperature of (22 ± 1) ℃ , and the other groups were placed inside a temperature and humidity controlled chamber pre-set at 37 ℃ and 60%. The two UTI groups were intraperitoneally injected with UTI at 5×104 U/kg 10 min before or after heat stress, and the two saline groups were given then equal amounts of saline in the same manner. The core body temperature of mice was monitored by a mercury thermometer every 30 min in the first 1.5 h during heating. The core temperature was measured, then every 15 min until it reached 42.7 ℃, which was taken as the onset of heatstroke. The animals were allowed to recover passively at ambient temperature for 6 h. The lung histopathological changes, protein concentration in BALF, lung wet/dry weight ratios, lung water content, and pulmonary microvascular permeability were assayed after 6 h of recovery at 37 ℃. Results Compared with the control group, the heatstroke model group and two saline groups displayed more severe lung damage and pathological morphology changes, and the lung wet/dry weight ratio, protein concentration in BALF, lung water content and pulmonary microvascular permeability were also significantly increased. These effects were significantly alleviated in UTI treated group. Pretreat ment with UTI significantly prolonged the time to Tc≥42.7 ℃ but had no effect on lung injury induced by heatstroke. Conclusion UTI can reduce the pulmonary edema and inflammatory exudation in acute lung injury caused by heatstroke.
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》
Abstract： Objective To investigate the molecular mechanisms of continuous venovenous hemofiltration (CVVH) combined with ulinastatin (ULI) (CVVH-ULI) for the treatment of septic shock. Methods Human umbilical endothelial cells (HUVECs) were incubated with serums isolated from normal healthy people (control), septic shock patients treated with conventional therapy (CT) or treated with CVVH combined with ULI (CVVH-ULI). Endothelial permeability was evaluated by the leakage of FITC-labeled albumin. The morphological changes of F-actin was evaluated by Rhodamine-phalloidin. The phosphorylated levels of p38 were determined by Western blot. Cells were then treated with p38inhibitor (SB203580), or DMSO, followed by incubation with serum from septic shock patients treated with conventional therapy. Endothelial permeability and F-actin rearrangements were also evaluated as noted above. Results Serum from CT group increased endothelial permeability, F-actin rearrangements, and phosphorylated levels of p38, which were inhibited by CVVH-ULI treatment. Moreover, in CT group, the serum-induced endothelial hyperpermeability and F-actin rearrangements were inhibited by SB203580, the inhibitor of p38. Conclusion CVVH combined with ulinastatin decreases endothelial hyperpermeability induced by septic shock through inhib- iting p38 MAPK pathways.
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