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  • Development and application of public and patient health popularization handbooks

    Subjects: Library Science,Information Science >> Library Science submitted time 2024-04-19

    Abstract: With the deepening of Healthy China, the level of public health literacy has significantly improved, and more and more patients are participating in joint decision-making. The Health Science Popularization Handbook provides the public and patients with the basis for knowing, choosing, and seeking support. It plays an important role in enhancing information balance in the medical process, promoting effective communication between doctors and patients, reducing patient uncertainty, and helping patients to actively respond to medical conditions. However, there is still a lack of guiding opinions on how to develop a Health Science Popularization Handbook in China. After more than three years of exploration, the team has developed a set of procedures and application methods for the development of a public and patient health science popularization handbook, which is widely applicable to health industry practitioners and public and patients who aspire to engage in health science popularization creation, in order to provide reference for the promotion of health science popularization work.

  • 开放科学:概况、问题与出路

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:开放科学自 20 世纪 90 年代发展至今虽然已被各界所认可,但发展较为缓慢,并没有成为科学界的主流。针对该问题, 在对开放科学国内外发展现状进行梳理的基础上,总结分析了影响开放科学发展的主要因素,并为我国开放科学的发展提出 设计开放科学国家政策,加大资金扶持力度,构建系统、深入的开放机制等 3 条实现路径。最后,对我国开放科学实践进行 了介绍分析,指出 OSID 这种模式为开放科学实践进行了非常有益的探索。

  • 学术论文科研诚信问题分析与解决路径探索

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:针对当前学术领域层出不穷的科研诚信丑闻,为了探索防范学术不端行为的有效路径,首先结合前人研究和典型案 例,对当前科研领域学术不端行为的主要类型进行了简要梳理,并在此基础上对学术论文科研诚信问题的成因进行了分析, 最后阐述了基于开放科学标识码(open science identity, OSID)的开放科学计划给出的解决路径。OSID 平台借助语音介绍、 在线问答、学术圈、开放内容和数据等功能,打造出一个在线互动交流的学术平台。该平台有助于建立更加公平合理的基于 单篇论文的学术评价机制,并大力促进开放科学运动的普及。面对学术不端的严峻环境,期刊社应发挥好科研诚信“把关人” 的作用,主动推进数字化转型,积极拥抱开放科学运动,逐渐形成期刊品牌效应。

  • 轻量化的现代期刊转型平台 ——OSID 的逻辑、功能及发展趋势

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:移动互联网时代,传统期刊转型面临困境,科技期刊对国家科技创新体系支撑力严重不足。因此,科技期刊转型应 该遵从突出核心轻量化、挖掘场景去中心、精细运营重传播的范式和逻辑。重点从 5 个维度介绍了基于开放科学计划(open science identity,OSID)的现代纸刊的功能实现和发展趋势,即:开放质量控制、学术社区构建、深度交互服务、创新知识呈现、 协同知识生产。

  • Neuropsychological Changes of Cognitive Reverters after Stroke Based on the Montreal Cognitive Assessment (MoCA)with a Double Threshold

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-05-05 Cooperative journals: 《中国全科医学》

    Abstract:  Background Cognitive function is dynamic in post-stroke patients,however,there are limited studies on cognitive recovery after stroke. The definition of cognitive reverters and neuropsychological characteristics according to various definitions have not yet been investigated. Objective To investigate the neuropsychological characteristics of cognitive reverters after stroke based on the traditional definition and new definition according to Montreal Cognitive Assessment (MoCA) with a double threshold. Methods A total of 163 patients hospitalized for first onset acute ischemic stroke were recruited from the Department of Neurology of the Second Hospital of Hebei Medical University from December 2020 to February 2022as the study subjects. All patients were assessed for cognitive function in the acute period of ischemic stroke using the MoCA at baseline. Cognitive function was assessed again at the 6-month post-stroke follow-up with the detailed neuropsychological tests refined at the same time,including the digit span task (DST),Stroop color and word test (SCWT),Chinese version of Boston naming test (BNT),verbal fluency test(VFT),clock drawing test(CDT),and auditory verbal learning test(AVLT). The enrolled patients were divided into the M1 group (MoCA scores <21),M2 group (21 ≤ MoCA scores ≤ 25)and M3 group (MoCA scores ≥ 26)according to the MoCA with adouble threshold. While the patients were also divided into the reverters 1(R1) group,nonreverters 1(NR1) group,R2group and NR2 group according to the two definitions of reverters. Results Patients were followed up after 6 months,of which 28 were lost to follow-up and 135 were finally included in the study. The average MoCA score in the acute period of stroke was (20.1±5.1) in 135 patients. There were 40 cases in the M1 group,61 cases in the M2 group and 34 cases in the M3 group. The scores of the MoCA,forward DST,reverse DST,total DST,Chinese version of BNT,CDT,Stroop C time consuming,numbers of VFT-animal,VFT-fruit and VFT-vegetable,AVLT-immediate scores,AVLT#2;short delay scores,AVLT-long delay scores and AVLT-recognition scores in the M2 and M3 groups6 months after stroke were higher than the M1 group(P<0.05).The scores of the MoCA,reverse DST,total DST,AVLT-short delay score and AVLT#2;long delay score in the M3 group than the M2 group(P<0.05).120 patients of the 135 patients with MoCA scores<26 in the acute period of ischemic stroke were selected as the study subjects. Compared with the MoCA scores during the acute period of ischemic stroke,73 patients improved ≥ 2 points during the follow-up period in the R1 group and 47 patients improved <2 points in the NR1 group,with a recovery rate of 60.8% (73/120).Patients in the R1 group had lower MoCA scores in the acute period of ischemic stroke than the NR1 group,and higher MoCA scores in the follow-up period than the NR1 group (P< 0.05).Compared with the double threshold classification of MoCA in the acute period of stroke,50 cases had increased scores and crossed over to the R2 group and 70 cases did not cross over to the NR2 group at follow-up,with a recovery rate of 41.7% (50/120).Patients in the R2 group had higher MoCA score in the acute period of stroke,MoCA scores,reverse DST scores,total DST scores,Chinese version of BNT scores,VFT-vegetable number,CDT scores,AVLT-immediate scores,AVLT-short delay scores,AVLT-long delay scores,and AVLT-recognition scores during follow-up were higher than the NR1 group,and the Stroop C time consuming,numbers of Stroop C errors and VFT-animals were lower than the NR1 group (P<0.05). Conclusion There are varying degrees of impairment in attention,visuospatial function and delayed recall in post-stroke patients. There is no significant difference in neuropsychological characteristics between reverters and nonreverters. However,the scores of reverters are higher based on the definition using double threshold for MoCA scores,which is more relevant for clinical use.
     

  • Analysis of neuropsychological characteristics of cognitive reverters after stroke based on the Montreal Cognitive Assessment (MoCA) with a double threshold

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-01-09 Cooperative journals: 《中国全科医学》

    Abstract:

    Background The cognitive function of patients after stroke is dynamic. However, our knowledge regarding cognitive recovery after stroke is limited. The neuropsychological characteristics of cognitive reverters after stroke using different definitions have not yet been investigated. Objective To investigate the neuropsychological characteristics of cognitive reverters after stroke based on the Montreal Cognitive Assessment (MoCA) with a double threshold. Methods A total of 163 patients hospitalized for acute first-episode stroke in the Department of Neurology, the Second Hospital of Hebei Medical University from December 2020 to February 2022 were admitted. All patients were assessed for cognitive function using the Montreal Cognitive Assessment (MoCA) at baseline.After 6 months of follow-up, the MoCA were performedon 135 patients. At the same time, detailed neuropsychological assessments, which includeddigit span test(DST),Stroop C,Boston naming test(BNT),Verbal fluency test(VFT),Clock drawing test(CDT),Auditory verbal learning test(AVLT)were performed.A double threshold resulted in three groups:M1 group with a score <21;M2 group with a score between 21 and 25; and M3 group with a score≥26. The patients were categorised into reverters and nonreverters using different definitions:R1 and NR1 group;R2 and NR2 group. Results The mean scores of DST,CDT,AVLT delayed recall varied significantly in three groups(P<0.05). Compared with M2 or M3 group,M1 groups showed impairments in Stroop C,BNT,VFT,AVLT immediate recall and recognition(P<0.05).There was no significant difference in the mean scores of Stroop C,BNT,VFT,AVLT immediate recall and recognition between M2 and M3 groups(P>0.05).R1 group had lower MoCA score at the acute stage and higher MoCA score in the follow-up period.However, there were no differences between R1 and R2 groups in 5 cognitive domains (attention, execution, language, visual space, episodic memory) (P>0.05). R2 group had higher MoCA scores and scores across 5 domains (attention, execution, language, visual space, episodic memory), with significant difference (P< 0.05).Conclusion Attention and delayed recall and visuospatial function were impaired to different degrees inpatients after stroke.Using traditional definition, there were no significant difference in neuropsychological characteristics between reverters and nonreverters. Based on the MoCA with a double threshold, reverters had higher scores. Therefore, new definition is closely related to clinical practice.

  • 基于动态柯西蜂群算法优化支持向量机的风机叶片故障诊断

    Subjects: Dynamic and Electric Engineering >> Electrical Engineering submitted time 2019-03-05 Cooperative journals: 《电气工程学报》

    Abstract:为了提高风力发电机叶片故障的识别率,利用支持向量机建立风力发电机 叶片故障和特征参数之间的非线性关系。在蜂群算法中引入一种动态柯西因子,动态 调节蜂群寻优过程中的搜索步长,提高蜂群算法的扰动能力,避免蜂群陷入局部搜索, 采用这种动态柯西蜂群算法对支持向量机的参数寻优,建立动态柯西蜂群算法优化的 支持向量机模型。采集南方某风场风力发电机叶片的四种工况下的特征数据训练此模 型并进行故障诊断,诊断结果表明改进后的蜂群算法优化支持向量机模型能够提高风 力发电机叶片的故障识别率,具有一定的工程参考意义。

  • 基于动态柯西蜂群算法优化支持向量机的风机叶片故障诊断

    Subjects: Dynamic and Electric Engineering >> Electrical Engineering submitted time 2019-03-05 Cooperative journals: 《电气工程学报》

    Abstract:为了提高风力发电机叶片故障的识别率,利用支持向量机建立风力发电机 叶片故障和特征参数之间的非线性关系。在蜂群算法中引入一种动态柯西因子,动态 调节蜂群寻优过程中的搜索步长,提高蜂群算法的扰动能力,避免蜂群陷入局部搜索, 采用这种动态柯西蜂群算法对支持向量机的参数寻优,建立动态柯西蜂群算法优化的 支持向量机模型。采集南方某风场风力发电机叶片的四种工况下的特征数据训练此模 型并进行故障诊断,诊断结果表明改进后的蜂群算法优化支持向量机模型能够提高风 力发电机叶片的故障识别率,具有一定的工程参考意义。

  • 气相色谱法对狂犬病疫苗灭活工艺中β-丙内酯研究

    Subjects: Biology >> Bioengineering submitted time 2019-01-17 Cooperative journals: 《中国生物工程杂志》

    Abstract:目的:基于GC-FID法,对狂犬病疫苗生产过程中采用的β-丙内酯灭活剂进行了含量及稳定性研究。方法:气相色谱条件:采用Agilent DB-624(30 m×0.530 mm×3.00 μm)毛细管柱;升温程序:初始温度为80 ℃,保持1 min,以20 ℃/min的速率升温至200 ℃,保持3 min;色谱柱流量:3 mL/min;检测器温度:250 ℃;进样口温度:150 ℃;载气:氮气,线速度:25 cm/sec;进样量:1 μL,分流比为2:1,进样方式:手动进样。结果:以乙腈作为稀释剂,BPL在1:100~1:32000范围内线性关系良好(R2≥0.999)。在1:200、1:1000、1:8000 三个浓度水平下,加标回收率在95.04%~116.86%之间,相对标准偏差(RSD)为2.6%~3.2%,检测限为0.112 μg/mL。结论:该方法简便、专属性强、稳定且在室温条件下操作,大大降低了对试验条件和技术操作的要求,能够满足灭活狂犬病病毒工艺中对BPL检测的需求。

  • 基于辨识特征后融合的行人再识别

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2018-05-24 Cooperative journals: 《计算机应用研究》

    Abstract: Pedestrian may vary greatly in appearance due to differences in illumination, viewpoint, and pose across cameras, which can bring serious challenges in person re-identification. This paper proposed discriminative feature based late fusion using multiple-feature fusion and distance metric learning for person re-identification. Firstly, it expressed human appearance across cameras through local maximal occurrence (LOMO) and salient color names-based color descriptor (SCNCD) extracted from human sample images across cameras. Secondly, it obtained each optimized feature distance of each pair of pedestrians through individual cross-view quadratic discriminant analysis (XQDA) distance metric learning model trained based on LOMO feature and SCNCD feature, respectively. Finally, it obtained the final distance of each pair of pedestrians across cameras through a distance fusion using min-max normalization, which was applied for human match across cameras. Experimental results have shown that the proposed algorithm effectively improves the accuracy of person re-identification on two challenging datasets (VIPeR, PRID450s) .

  • 不同供水下白羊草(Bothriochloa ischaemum)离体根呼吸特征——基于稳定碳同位素示踪技术

    Subjects: Biology >> Ecology submitted time 2018-05-18 Cooperative journals: 《生态学报》

    Abstract:植物根呼吸是土壤呼吸的主要组成,研究根呼吸对生态系统碳收支及碳平衡有重要意义。采用13C脉冲标记技术,在3种供水条件下,对比不同根离体时间(标记后0,6,24,48,216,360 h)的白羊草离体根呼吸速率和根呼吸释放的δ13C同位素比值变化,分析根参数与离体根呼吸相关性。结果表明:1)不同离体时间的离体根呼吸速率变化趋势一致,3种供水条件下无显著差异,均在0-20 min急剧下降,下降范围为32%-39%。2)测定离体根呼吸释放的δ13C在不同离体时间的变化,为实时监测转移到白羊草根系的13CO2在根部释放的过程提供了新思路;不同离体时间,3种供水条件下根呼吸释放的δ13C在2 h内均值大小呈:供水充分 > 轻度胁迫 > 重度胁迫。随离体时间(0-360 h)推移根呼吸释放的δ13C均值先增大后减小,在216 h达到峰值31.46‰;3)离体根呼吸速率和根呼吸释放的δ13C受根系根面积、比根面积、N含量、C/N及根组织δ13C的影响显著。4)轻度水分胁迫可促使根系生长(C固定)和根呼吸(C代谢)同时增加。