Subjects: Nursing >> Nursing submitted time 2024-05-28
Abstract：1例老年女性压力性尿失禁患者的护理经验。住院期间进行中西医联合疗法治疗，护理要点包括：康复训练护理，耳穴压豆治疗，用药护理，心理护理等。经过治疗和护理，患者压力性尿失禁情况明显好转。
Peer Review Status:
Awaiting Review
Subjects: Nuclear Science and Technology >> Radiation Physics and Technology submitted time 2024-05-28
Abstract： Ion beam radiotherapy is increasingly being used for tumor treatment. Currently, the use of traditional X-ray computed tomography (CT) for treatment planning of ion-beam radiotherapy has significant relative stopping power (RSP) errors. A more ideal approach is to directly use ion beams to generate patient images for treatment planning so as to avoid RSP conversion and reduce RSP errors. In this study, the Monte Carlo program Geent4/Gate was adopted to establish an ion-CT simulation platform, designed two sets of ion CT systems, ideal and real, and reconstructed images using the maximum likelihood method and ASD-POCS algorithm. The effects of the ideal and real settings, multiple energies, and different ion types on the RSP error of phantom reconstruction were investigated. The results show that the relative error of RSP for 330MeV protons in both the ideal and real settings was less than 1.547%, and the RSP reconstruction error in the ideal settings was much smaller than that in the real settings. The RSP reconstruction error of each material under realistic settings is close to three times that under ideal settings. The relative errors of RSP for protons decrease with the increase of incident energy. The relative errors of RSP were the biggest at 230MeV, and were2.855%、2.468%、1.653%、and 2.553% in sulfur, phosphorus, carbon, and calcium materials. The RSP relative error reached its minimum at 330MeV, with 0.181%, 0.351%, 0.250%, and 0.245% in sulfur, phosphorus, carbon, and calcium materials. At energy of 330MeV/u for carbon ions , the RSP relative errors in sulfur, phosphorus, carbon, and calcium materials were 0.060%, 0.281%, 0.150%, and 0.082%, respectively, all within 0.281%. And the RSP relative errors were much smaller than those of protons under the same conditions. Thus, compared with proton CT, carbon ion-beam CT seems more possible to provide accurate RSP data for treatment planning for ion-beam radiotherapy..
Subjects: Nuclear Science and Technology >> Nuclear Science and Technology submitted time 2024-05-28
Abstract： The search and localization of unknown radioactive sources is an important research topic in the field of nuclear security inspection and nuclear emergency response. In order to improve the source finding efficiency and adapt to the multi-source environment detection, a particle filtering source finding method integrating the angle of arrival is proposed. Firstly, a hardware platform combining autonomous localization and angle-of-arrival sensing is constructed to introduce position and angle information to the detector; secondly, the angle-of-arrival information is taken into account on the basis of particle filtering, which can dynamically shrink the source searching area and improve the searching efficiency; lastly, the angle-of-arrival-guided robot attitude adjustment is adopted in the path planning of the autonomous source searching, which can enhance the flexibility of the robot in searching for the source. Simulation experiments prove that this method can work correctly and effectively, and tests using radioactive sources further verify the practicality of this method for multi-source search.
Subjects: Psychology >> Other Disciplines of Psychology submitted time 2024-05-27
Abstract： Depression-induced suicide is the second leading cause of death among adolescents, and prolonged mobile phone usage has emerged as a significant public health concern with this demographic. However, the relationship between the duration of mobile phone usage and the manifestation of depressive symptoms in adolescents remains unexplored. This study aims to investigate the characteristics, evolution patterns, and gender differences in depressive symptoms among adolescents based on varying durations of mobile phone usage, as well as to provide new strategies for the prevention and control of depression among them. A large-scale survey was conducted on 167,728 adolescents in Nanchong City using the 20-item Center for Epidemiological Studies Depression Scale (CES-D). Mobile phone usage was categorized as follows: Non-use on rest days (T1), usage on rest days for ≤3 hours per day (T2), and usage on rest days for >3 hours per day (T3). The collected data were analyzed using R software (version 4.3.2) and its network analysis packages. The study compared the differences in the depressive symptom networks among adolescents with varying duration of mobile phone usage on rest days, as well as the differences between genders for the same mobile phone usage duration. Network analysis revealed that the longer the duration of mobile phone usage among adolescents, the more severe the symptoms of depression. Among the symptoms of depression in adolescents, ’sadness’, ’sense of failure’, ’lack of pleasure’, and ’lack of happiness’ have a higher degree of strength centrality. We performed a comparative analysis of the depression symptom network under different mobile phone usage durations on rest days. There were no significant differences in global strength and network edges between the T2 and T1 networks, but a significant difference in network structure, with the strength centrality of one symptom being significantly different. The T3 vs. T1 network showed significant differences in global strength, network structure, and network edges, with 32 edges showing significant differences and the strength centrality of 8 symptoms being significantly different. The T3 vs. T2 network also showed significant differences in global strength, network structure, and network edges, with 19 edges showing significant differences and the strength centrality of 10 symptoms being significantly different. Additionally, we also revealed the comparative analysis of the depression symptom network among different genders with the same mobile phone usage duration on rest days. Under the T1 condition, there were no significant differences in network structure and network edges between the female and male groups, but a significant difference in global strength, with the strength centrality of one symptom being significantly different. Under the T2 and T3 conditions, there were significant differences in global strength, network structure, and network edges between female and male groups. Under the T2 condition, there were significant differences in 25 edges and the strength centrality of 8 symptoms. Under the T3 condition, there were significant differences in 15 edges and the strength centrality of 5 symptoms. The current study indicated that the characteristics and evolution patterns of depressive symptoms in adolescents varied according to the duration of mobile phone usage, and notable gender differences. This study, based on the evolution patterns of various depressive symptoms, innovatively proposes four evolution patterns of depressive symptoms. This findings provide new strategies for the prevention and control of adolescent depression.
Peer Review Status:Awaiting Review
Subjects: Materials Science >> Materials Science (General) submitted time 2024-05-27
Abstract： Manufacturing hydrogels with identical electrochemical properties are typically riddled with unresolved inquiries and challenges. Here, we utilized ultra-light graphene flakes to trace the influence of convection phenomena during reactions on hydrogels’ formation and structural non-uniformity, elucidating its mechanisms. Furthermore, we confirmed that an external electric field induced the orientation of functional groups of hydrogels along the direction of this field, revealing the mechanism of its influence on the structural non-uniformity and electrochemical properties of hydrogels. Additionally, we discovered that ion diffusion was Stumbling-to-Fetters by the functional groups on the polymer chains within the hydrogel, unveiling this mechanism and developing the Virginia Creeper (VC) model for hydrogels. We demonstrated the scalability and application of the VC model. Furthermore, we proposed a molecular-ion diffusion and current decay equation to describe the electrochemical properties of hydrogels. As an application of the VC model, we developed a bionic cardiovascular system and proved its potential to seamlessly interface with living organisms and generate bio-like bioelectricity. Our findings provide novel insights into triboelectricity and guidance for producing hydrogels with identical electrochemical properties, and offer a new pathway for bioelectric generation and the design of new hydrogel devices.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Acute ischemic stroke（AIS）is characterized by high rates of disability，mortality，and recurrence，posing a significant burden on patients and society. In the era of big data，predictive models are increasingly used in patient diagnosis，treatment decisions，prognosis management，and healthcare resource allocation，highlighting their growing importance. Machine learning methods have become a crucial tool for predicting the prognosis of AIS patients and have been widely applied. This review explores recent advancements in the study of AIS prognosis prediction，focusing on machine learning methods. It discusses current issues and challenges faced by machine learning models，aiming to provide new insights and references for methods of early assessment and prediction of prognosis outcomes in AIS patients.
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Background Previous studies have found that inter-arm blood pressure difference（IAD）and mild cognitive impairment（MCI）are both associated with cardiovascular risk factors，but it is unclear whether there is an association between IAD and MCI. Objective To explore the relationship between IAD and MCI in rural elderly persons and to provide a scientific basis for clarifying the mechanisms of cognitive decline in elderly persons. Methods From July to August 2019，the rural elderly residents aged 60 years and older were selected using the multi-stage cluster sampling method from 5 townships in 2 counties（districts）of Guizhou Province，and questionnaire surveys，general physical examinations，cognitive function assessments，and bilateral arm blood pressure measurements were carried out among them. Cognitive function was evaluated using the Mini-Mental State Examination（MMSE） scale，and activities of daily living were assessed using the Activities of Daily Living（ADL） scale. Spearman rank correlation analysis and binary logistic regression model were used to investigate the association between IAD and MCI in the elderly persons. Results A total of 1 795 questionnaires were distributed，and data from 1 088 participants were finally included in the study by excluding subjects with incomplete information on the questionnaires，those who did not undergo blood pressure measurements，and those who did not undergo blood tests. Among the 1 088 rural elderly residents，138 patients（12.68%）with MCI，99 patients（9.10%）with systolic inter-arm blood pressure difference（sIAD） ≥ 10 mmHg，and 80 patients（7.35%）with diastolic inter-arm blood pressure difference（dIAD） ≥ 10 mmHg were detected. Individuals with IAD ≥ 10 mmHg had a higher prevalence of MCI and lower MMSE scores，orientation scores，language scores，and delayed recall scores compared to those with IAD <10 mmHg （P<0.05）. The results of correlation analysis showed that the sIAD was significantly negatively associated with the total MMSE score （rs=-0.094），orientation score （rs=-0.082），verbal ability score （rs=-0.065） and delayed recall score （rs=-0.104）；and the dIAD was significantly negatively associated with the total MMSE score （rs=-0.080），orientation score （rs=-0.094），and attentional calculation score （rs=-0.063）（all P<0.05）. Multivariate logistic regression analysis showed that the risk of MCI increased by 8.80% for each 1 mmHg increase in sIAD （OR=1.088，95%CI=1.046-1.131；P<0.001）；sIAD ≥ 10 mmHg （OR=2.169，95%CI=1.262-3.728；P<0.05） and dIAD ≥ 10 mmHg （OR=1.926，95%CI=1.047-3.542；P<0.05） were the influencing factors for the occurrence of MCI in the elderly. Conclusion The prevalence of MCI in rural elderly was 12.68%，and their elevated IAD was associated with an increased risk of MCI. And the risk of MCI was higher in elderly with IAD ≥ 10 mmHg than in those with IAD <10 mmHg.
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Background Although the number of case reports on pulmonary infarction（PI）secondary to pulmonary embolism（PE）is increasing in recent years，its misdiagnosis remains common，mainly as pneumonia. In patients with intermediate and high-risk pulmonary embolism，delays in diagnosis and timely treatment would lead to poor prognosis. Objective By analyzing the pneumonia-misdiagnosed cases of patients with PI，we summarized their clinical characteristics and related risk factors，and constructed a multivariate joint model to improve the accurate diagnosis rate at early stage. Methods This retrospective study included the hospitalized patients with pulmonary embolism at the First Affiliated Hospital of USTC from January 2017 to December 2023. In the group of pneumonia-misdiagnosed patients with intermediate to high-risk PI，we analyzed the clinical characteristics and compared the differences between the misdiagnosed groups and control group. Furthermore，using a multivariate logistic regression analysis，we explored the independent predictive factors of the delayed diagnosis，analyze the predictive value of various indicators for the misdiagnosis by ROC curves，and compared the AUC values using Delong test. Results Among 101 cases of PI patients，70 of them were misdiagnosed as pneumonia. Comparing with the control group，the characteristics of misdiagnosed patients were old age，higher incidences of fever and chest pain with unlikely presence of dyspnea. From 2017 to 2023，the misdiagnosis rate gradually decreased in percentages of 100.0%，83.3%，74.1%，71.4%，63.2%，66.7%，and 50.0%，respectively. Based on the results of multivariate logistic regression analysis，the characteristics of over sixty-years-old age（OR=18.271，95%CI=4.373-76.339，P<0.001），fever（OR=16.073，95%CI=3.510-73.786，P<0.001），chest pain（OR=6.660，95%CI=1.571-28.233，P=0.010）and non-dyspnea（OR=9.027，95%CI=2.049-30.249，P=0.003）were independent predictive factors for the misdiagnosis. Therefore，a multivariate joint model was constructed as the following equation：Y=-6.624+0.095×A（factor of age）+2.510×F（factor of fever）+2.683×N（factor of non-dyspnea chest pain）. The model indicated the PI misdiagnosis parameters as AUC under the curve（OR=0.880，95%CI=0.802-0.959，P<0.001），best cutoff value（0.854），sensitivity（0.871）and specificity（0.806）. Therefore，the predictive values are superior to single-factor indicators of age（Z=2.771，P=0.006），fever（Z=4.653，P<0.001）and non dyspnea chest pain（Z=4.014，P<0.001）. Conclusion Although the misdiagnosis rate of pulmonary infarction has decreased in recent years. Clinicians should keep alert to the differential diagnosis of pulmonary infarction and pneumonia in elderly PE patients with symptoms of fever and non-dyspnea chest pain.
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Background In patient involvement，patients are transforming from mere recipients to collaborators in medical services by integrating their experiences and needs throughout the entire healthcare process into medical practice. This aims to enhance the effectiveness，efficiency，and quality of healthcare services. However，the implementation of proven patient#2;centered strategies for patient involvement in the quality improvement among chronic obstructive pulmonary disease（COPD）in our country remains to be explored.Objective This scoping review systematically reviews and analyzes the existing strategies for patient involvement among patients with COPD to provide a reference for implementation that in China.Methods Employing the scoping review guidelines of Joanna Briggs Institute in Australia as the methodological framework，the relevant studies on patient involvement among patient with COPD were searched by computer on PubMed，Embase，Cochrane Library，CNKI，Wanfang Database，China Biology Medicine disc. A thematic analysis was methodically applied to distill and synthesize findings. Results A total of 37 articles were included in this review. The categorization of patient involvement was divided into three types：direct involvement in medical care，organizational-level，and clinical research. Based on the intensity of involvement，categories were further classified into three levels：consultation，engagement，and collaborative leadership. A nine-category matrix of patient involvement behaviors was constructed through intensity and type. The implementation of COPD patient engagement was primarily reflected in five categories encompassing eight behaviors，including：integration in direct medical care（patients expressing their preferences and wishes regarding treatment plans）；consultation at the organizational management level（assessing patient treatment experiences and organizing discussions around patients' concerns）；as well as involvement in clinical research，including consultation（listening to patient needs）and engagement（expressing preferences and wishes for interventions，involved in the development of assessment tools，and in discussions about research design and implementation）. Assessing patient treatment experiences（10 articles，27.03%）and expressing patient preferences and wishes regarding interventions（10 articles，27.03%）were the two most frequently implemented behaviors of patient involvement in COPD. Conclusion There are numerous measures for patient involvement in the improvement of medical quality，but there is still limited practice in the field of COPD. Very few studies have assessed the impact of patient involvement on clinical outcomes and quality of life，indicating that the practice of patient involvement in China requires further exploration.
Subjects: Psychology >> Other Disciplines of Psychology submitted time 2024-05-27
Abstract： Judgments of learning (JOLs) refer to learners’ subjective predictions of whether they can successfully extract what they have learned on future tests. Face memory is an important foundation for acquiring information during social interactions and ensuring that social activities are carried out properly. Emotion and attractiveness are two important cues that influence JOLs of face memory. In reality, emotion and attractiveness often appear simultaneously in the same face. However, previous studies have only examined the effects of the two cues on JOLs individually, and have not deeply explored the effects of the integration of the two cues on the accuracy of JOLs and their mechanisms./t/nThe present study first explored the proportion of the number of emotional and attractive cue integrators. Then, we increased the gradient of each level of the attractiveness cue in Experiment 1, and utilized a mixed experimental design of 2 (group: cue-integrated group, non-cue-integrated group) × 3 (emotional cue: high-intensity, medium-intensity, and low-intensity) × 3 (attractiveness cue: high-intensity, medium-intensity, and low-intensity) to explore whether the cue-integration could improve face memory and the accuracy of JOLs. In Experiment 2, in order to further improve the sensitivity of the subjects to the two cues, the mixed experimental design was changed to 2 (group: cue-integration group, non-cue-integration group) × 2 (emotional cues: high intensity, low intensity) × 2 (attraction cues: high intensity, low intensity), and the EEG was used to investigate the temporal characteristics of cue-integration in promoting the accuracy of JOLs./t/nFindings: (1) Subjects integrated both emotion and attraction cues for JOLs ratings(the pre-experiment). (2) Integrating emotional and attractiveness cues improved the accuracy of JOLs (Experiment 1). (3) The group that integrated cues had a higher amplitude of late positive waves (LPP) in the parietal region during the encoding stage and late negative waves (NSW) in the frontal region during the JOLs stage compared to the group that did not integrate cues. Additionally, the amplitudes of NSW and LPP in the cue-integrated group were significantly correlated with the accuracy of JOLs(Experiment 2). The study found that individuals who integrated emotion and attractiveness cues during the encoding stage were better able to allocate cognitive resources for cognitive assessment and retain information in the JOLs stage. This led to more accurate monitoring of their own face memory. The study suggests that integrating two cues can improve cognitive performance./t/nThis study offers a foundation for individuals to comprehend the impact of cue integration on memory and metamemory in real-world face learning scenarios. It also aids in the development of effective learning plans and strategies, as well as precise monitoring of the learning process.
Peer Review Status:Awaiting Review
Subjects: Nuclear Science and Technology >> Nuclear Detection Technology and Nuclear Electronics submitted time 2024-05-27
Abstract： Shielding material is critical for downhole pulsed neutron tool design as it directly influences the accuracy of formation measurements. A well-designed shield configuration ensures that the response of the tool is maximally representative of formation without being impacted by tool and borehole environment. This manuscript investigates the effects of boron-containing materials on neutron and gamma detectors based on a newly designed logging-while-drilling tool, which is currently undergoing manufacturing process. As boron content increases, its ability to absorb thermal neutrons significantly enhances. Through simulation, it is proven that boron carbide (B4C) can be used as an effective boron shielding material for thermal neutrons and therefore employed in this work. To shield against thermal neutrons migrating from mud pipes, the optimal shielding thicknesses for near and far neutron detectors are determined to be 5mm and 4mm. For an example, at a porosity of 25 p.u., the near neutron sensitivity shows a 5.6% increase in response. Furthermore, in order to shield capture gamma generated by thermal neutrons once they enter tool from the mud pipe and formation, the internal and external shields for the gamma detector is evaluated. Results show internal shield needs 75% boron content while the external shield is of 14.2mm thickness and 25% boron content to minimize tool effect.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Background Hypertension is a common chronic disease that seriously endangers the health of the population. The primary-care doctors are the main force in the management of hypertension. However，the doctor-induced therapeutic of inertia greatly affects the achievement of primary-care hypertension control. Objective The aim of this study is to investigate the current status of therapeutic inertia among primary healthcare providers in the diagnosis and treatment process of hypertension，and analyze the causes of therapeutic inertia，providing a reference basis for improving hypertension control rates in China. Methods A simple random sampling method was used to distribute questionnaires to primary healthcare providers in 32 primary healthcare institutions in Tianjin from July to August 2023. The therapeutic inertia in the diagnosis and treatment process of hypertension was evaluated from three dimensions: knowledge mastery of hypertension diagnosis and treatment，“soft reasons”and “overestimation of treatment efficacy” as well as “medical insurance policies.” Binary logistic regression analysis was employed to explore the influencing factors of therapeutic inertia.Results A total of 407 questionnaires were distributed in this study，and 386 valid questionnaires were collected，yielding an effective response rate of 97.96%. (1) The average score for primary healthcare providers' knowledge of hypertension diagnosis and treatment was 6 (0.5)，with a scoring rate of 61.19% (5.50/9.00). The total score for therapeutic inertia in hypertension management was 48 (7.0)，with a scoring rate of 56.55% (45.24/80.00). (2) The scores for the “soft reasons” dimension，“overestimation of treatment efficacy” dimension，and “medical insurance policies” dimension were 26 (4.8)，10 (2.0)，and 6 (2.5) respectively，with scoring rates of 51.97% (25.89/50.00)，65.42% (9.81/15.00)，and 44.64% (6.96/15.00) respectively. When comparing the average scores of the three dimensions of therapeutic inertia，the “medical insurance policies” dimension had the lowest score compared to the other two groups (P<0.05). Multivariate analysis showed that male gender，rural areas，lower mastery of hypertension diagnosis and treatment knowledge，and a weekly patient volume of less than 10 hypertensive individuals were associated with a higher tendency towards therapeutic inertia among primary healthcare providers (P<0.05). Conclusion therapeutic inertia is prevalent among primary healthcare providers in the diagnosis and treatment process of hypertension. Low levels of hypertension treatment cognition，overestimation of treatment efficacy，and “soft reasons” are the primary factors contributing to therapeutic inertia among primary healthcare providers. It is recommended to strengthen education on therapeutic inertia in hypertension，conduct diversified training on diagnostic and management knowledge，and promote clinical informatization and artificial intelligence decision-making systems to effectively improve the therapeutic inertia of primary healthcare providers in hypertension management.
Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-05-27 Cooperative journals: 《中国全科医学》
Abstract： Background Diabetes mellitus is difficult to cure and has a long process . The level of self-care is crucial for determining the regression and health outcomes of patients with diabetes. A comprehensive and theory-based tool is urgently needed to assess the level of self-care of diabetes. In this way，the self-care of patients with diabetes can be kept up to date and accurate nursing care can be carried out. Objective To examine the psychometric properties of the Chinese version of Self-care of Diabetes Inventory（SCODI），and provide a scientifically validated assessment tool for the self-care of Chinese patients with diabetes. Methods The Brislin Translation Model was used for translation and cultural adaptation of the English version of the SCODI into Chinese. A total of 261 adult patients with diabetes were enrolled using a consecutive sampling method at the First Affiliated Hospital and the Affiliated Sir Run Run Hospital of Nanjing Medical University from December 2022 to June 2023. Data were collected using a self-developed general information questionnaire and the Chinese version of SCODI. Exploratory factor analysis was used to assess the structural validity. Cronbach's α，split-half reliability and composite reliability were used to describe the reliability. Glycosylated hemoglobin was used as a criterion to assess the criterion-related validity. Spearman's rank correlation analysis was used to examinate the correlation between the Chinese version of SCODI score and glycosylated hemoglobin. Results The Chinses version of SCODI contained 4 dimensions and 40 items：self-care maintenance score（75.94±13.15），self-care monitoring score（70.65±18.71），self-care management score（69.16±18.24），and self-care confidence score（85.41±13.63）. In the self-care maintenance dimension，4 factors were identified：complication screening behaviors，exercise behaviors，hygienic care behaviors and diet-medication behaviors. The self-care monitoring dimension had 2 factors：physical monitoring and symptom identification. The self-care management dimension included 2 factors：autonomous behaviors and counseling behaviors. Two factors were extracted from the self-care confidence dimension：monitoring and managing confidence，health maintenance confidence. The Cronbach's α，split-half reliability and composite reliability values for the total scale were 0.915，0.836 and 0.912，respectively. The Cronbach's α for the four dimensions were 0.709-0.908. A significantly negative correlation was observed between each subscale and glycosylated hemoglobin（rs=-0.160，-0.300，-0.177，-0.192；P<0.001），serving as a criterion. Conclusion Based on the middle-range theory of self care of chronic illness，the Chinese version of SCODI exhibits strong psychometric properties，making it a valid and reliable instrument for evaluating self-care of Chinese patients with diabetes.
Subjects: Management Science >> Other Disciplines of Management Science submitted time 2024-05-26
Abstract： The misuse and abuse of NHST (null hypothesis significance test) and p value are quite serious in scientific research. NHST is a hybrid of Fisher’s significance test and N-P hypothesis test. But how is it mingled and how is it reflected in the calculation steps? Where are the logical flaws in NHST and p value calculations? There are no detailed and simple answers to these questions. Expounding, analyzing and comparing the steps of Fisher’s significance test, N-P hypothesis test and NHST clearly, combined with a typical example for the logical defect analysis of NHST and p-value calculations, can provide some inspiration for the empirical researchers who are not deeply involved in the field of statistics.
Peer Review Status:Awaiting Review
Subjects: Nuclear Science and Technology >> Radiation Physics and Technology submitted time 2024-05-26
Abstract： The Very Large Area gamma-ray Space Telescope (VLAST) is a mission concept proposed to detect gamma#2;
ray photons through both Compton scattering and electron-positron pair production mechanisms, thus enabling
the detection of photons with energies ranging from MeV to TeV. This project aims to conduct a comprehensive
survey of the gamma-ray sky from a low-Earth orbit using an anti-coincidence detector, a tracker detector
that also serves as a low-energy calorimeter, and a high-energy imaging calorimeter. We developed a Monte
Carlo simulation application of the detector using the GEANT4 toolkit to evaluate the instrument performance,
including the effective area, angular resolution, and energy resolution, and explored specific optimizations of
the detector configuration. Our simulation-based analysis indicates that the current design of the VLAST is
physically feasible, with an acceptance above 10 m2 sr which is four times larger than that of the Fermi-LAT,
an energy resolution better than 2% at 10 GeV, and an angular resolution better than 0.2 ◦ at 10 GeV. The
VLAST project promises to make significant contributions to the field of gamma ray astronomy and enhance
our understanding of the cosmos.
YES
Subjects: Psychology >> Applied Psychology Subjects: Psychology >> Social Psychology submitted time 2024-05-26
Abstract： Orderly display, from our urban planning to the layout of goods in shops, is widely used in our nearby environment. Researches have shown that the need for order is one of the basic human needs and people prefer objects under orderly display. Our study enriched this line of work by exploring the association between display order and product attribution and providing evidence that disorder can be beneficial. Specifically, natural attribution (vs. artificial product) is associated with disorder (vs. order). Furthermore, for natural product (vs. artificial product), consumers prefer them in disorderly display (vs. orderly display). Based on the associative learning mechanism, 4 studies were conducted to examine how display order and product attribute match together and influences consumers’ product preference. Also, the mediating role of fluency perception and moderating role of valence cue were examined.
Study 1 (N = 34, 18 men) intended to explore the matching relationship between product attribution and display order with the method of Implicit Association Test. Participants were instructed to sort a series of stimuli into two categories(natural or artificial) as quickly as possible. Study 2 (N = 280, 105 men) aimed to test the match effect of product attribution and display order in explicit level using within-subjects design. After showing the interpretation of both constructs’ definition, participants were asked to match natural (vs. artificial) product to orderly or disorderly display. Study 3 (N = 200, 75 men) used between-subjects design to further investigate the effect of product attribution and display order on consumer preference, and the mediation role of processing fluency, with product content remain the same, i.e., mango. Participants were shown one picture and asked to indicate their preference and processing fluency. Study 4 (N = 240, 98 men) investigated the boundary effect of valence cue. The participants were asked to evaluate the valence of all categories of product attribution and display order as priming method. Then participants were shown two pictures of natural or artificial product in disorderly and orderly display. In the end, they indicate their liking and processing fluency of pictures.
The main results of this study are as follows: (1) natural attribution (vs. artificial product) is associated with disorder (vs. order) in both implicit and explicit level; (2) for natural (vs. artificial) product, consumers have higher preference for product in disorderly (vs. orderly) display; (3) product attribution and display order influences consumers’ product preferences through the mediation role of processing fluency; (4) valence cue moderate consumers’ preference for natural products in different display order.
This research identify and explore a previously unidentified lay theory, the natural (vs. artificial) = disorder (order) intuition. Moreover, based on dual-process of associative learning, we further explore the contradictory naïve theory of our proposal. And this research contributes to the literature of natural product and product display. It provides managers with guidelines on arrangement of display order for product with different attribution when organizing shelf display or designing advertisement.
Subjects: Nuclear Science and Technology >> Nuclear Science and Technology submitted time 2024-05-26
Abstract： [Background]: CF series fuel assemblies are the key reactor-core components of the advanced third-generation nuclear power, which are independently developed by China National Nuclear Corporation(CNNC). [Purpose]: The purpose is to analyze the friction force and rod drop performance of CF2 fuel assembly combined control rod drive line moving parts in water and air under different eccentricity. [Methods]: a 1:1 simulated fuel assembly was used in the test with an independently-developed rotatable top cap. The integration of multiple eccentric was initially implemented for scientific and accurate regulation. [Results]: The friction force and rod drop performance data in water and air at different heights and under different eccentric conditions were obtained. The total rod drop time and the time for rod reaching the buffer increased with the increase of eccentricity while the buffer time was basically constant. The fuel assembly and control rod functioned properly under the maximum eccentricity. The friction did not exceed the allowable limit. And no jamming of control rod occurred under large eccentric condition. [Conclusions]: The experimental results provide an important experimental basis for the design optimization , safe evaluation and software development of CF fuel assembly. The method can be extended to the subsequent CF3 and other fuel assembly scientific research projects.
Subjects: Biology >> Biochemistry submitted time 2024-05-25
Abstract： Drug addiction is a serious chronic relapsing brain disease, and methamphetamine dependence has a complex course and is difficult to treat, causing a serious public health burden. In this study, we compared and analyzed the urine proteome of methamphetamine-using patients (patients who stopped using methamphetamine within 24 hours), methamphetamine-withdrawing patients (patients who stopped using drugs for more than 3 months and entered rehabilitation treatment), healthy individuals. The urine proteome of methamphetamine-addicted patients (including patients who were using methamphetamine and methamphetamine-withdrawing patients) was significantly different from that of healthy individuals, and some differential proteins and their enriched biological functions showed that they were associated with addiction or neurotoxicity of methamphetamine and may be potential intervention targets for drug addiction. Patients who withdrew methamphetamine for more than 3 months were still difficult to return to normal levels and may be used to reveal the reasons for the high rate of methamphetamine relapse. In this study, a method of studying addictive drugs from the perspective of urine proteomics was established, which proved that urine proteome can reflect the effects of methamphetamine abuse on the body relatively systematically and comprehensively, and has the potential to provide clues for the study and practice of clinical addictive diseases.
Peer Review Status:Awaiting Review
Subjects: Biology >> Biochemistry submitted time 2024-05-25
Abstract： Taking compound nutrient supplements is a common means of health management. No studies have investigated the overall effects of complex nutrient supplements on healthy individuals from the perspective of the urine proteome. In this study, we compared and analyzed the urine proteome of healthy individuals after taking compound nutrient supplements for 2 weeks, 4 weeks and before taking them, and found that the urine proteome changed more significantly after taking compound nutrient supplements for 2 weeks, and the differential proteins and their enriched pathways may be associated with nutrient supplementation, such as erythropoietin receptor (fold change of 449.5 after taking compound nutrient supplements for 2 weeks). The results of this study provide new clues about the health effects of complex nutrient supplements from the perspective of the urine proteome and help to optimize guidelines and recommendations for the use of complex nutrient supplements.
Peer Review Status:Awaiting Review
Subjects: Nuclear Science and Technology >> Nuclear Science and Technology submitted time 2024-05-25
Abstract： Due to only extracting a single feature of the vibration signal of the nuclear power unit, the detection effect of the vibration fault detection method for nuclear power units is poor. Therefore, a vibration fault detection method for nuclear power units based on DBN and multi-sensor data decomposition was designed. Obtain vibration signal data of nuclear power units, smooth and fuse the obtained multi-sensor data, extract multiple features of the vibration signal of nuclear power units under the action of DBN, calculate the sensitivity index and fuzzy entropy of different features, analyze the characteristics of the vibration signal, construct a corresponding vibration fault detection model, and solve the vibration fault signal of nuclear power units. The experimental results show that in the practical application of this method, the AUC-ROC curve area is closer to 1, and the detection effect is better.
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