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  • The Evaluation of Effective-component Compatibility of Bufei Yishen Formula Ⅲ and Components Compatibility in Treating Airway Remodeling of COPD

    Subjects: Medicine, Pharmacy >> Preventive Medicine and Hygienics submitted time 2024-03-26 Cooperative journals: 《中国全科医学》

    Abstract: Background  Obstructive pulmonary disease(COPD)is a major chronic disease,and airway remodeling is an important pathological mechanism. Bufei Yishen formula and effective-component compatibility of Bufei Yishen formula Ⅲ(ECC-BYF Ⅲ)are effective for COPD treatment. ECC-BYF Ⅲ significantly improves airway remodeling of COPD model rats,however,the components compatibility remains to be revealed. Objective  To evaluate the effect of ECC-BYF Ⅲ and components compatibility in treating airway remodeling of COPD based on the COPD rat model. Methods  The components of ECC-BYF Ⅲ were divided into four categories:Buqi,Bushen,Huatan,and Huoxue. The four categories were divide into different groups according to the method of mathematical permutation. The animal experiment were performed during May to September in 2018. 216 SD rats were randomly divided into normal,model,ECC-BYF Ⅲ,different components compatibility and aminophylline groups,and 12 rats in each model. From week 1 to week 8,rat model of COPD in stable phase was established by cigarette smoke exposure combined with repeated bacterial infections. The rats were orally gavaged with corresponding drugs from week 9 to week 16. Hematoxylin eosin(HE)staining technique was used to observe the changes of bronchial wall and airway smooth muscle. Enzyme linked immunosorbent assay(ELISA)was used to detect the levels of matrix metalloprotein 12(MMP-12),basic fibroblast growth factor(bFGF)in serum and levels of collagen(COL)-1,COL-3,and MMP-12 in bronchoalveolar lavage fluid(BALF). Region(R)value comprehensive evaluation method was used to evaluate the effect of different component compatibility on airway remodeling in COPD rats. Results  ECC-BYF Ⅲ,different components compatibility and aminophylline weakened the thickness of airway wall,when compared to model group. ECC-BYF Ⅲ,Buqi Huatan,Fuzheng Huatan,Fuzheng Huoxue,Buqi Quxie and aminophylline significantly decreased the number of airway smooth muscle hyperplasia(P<0.05). When compared to model group,the level of bFGF in serum decreased in ECC-BYF Ⅲ,Bushen,Buqi Huatan,Buqi Huoxue,Bushen Huatan,and Bushen Huoxue groups. The level of MMP-12 in serum decreased ECC-BYF Ⅲ,Fuzheng groups. The levels of MMP-12,COL-1 in BALF decreased in ECC-BYF Ⅲ,different components compatibility and aminophylline groups. The level of COL-3 in BALF decreased in ECC-BYF Ⅲ,Bushen,Huatan,Huoxue,Fuzheng,Buqi Huatan,Buqi Huoxue,Bushen Huoxue,Fuzheng Huatan,Buqi Quxie,Bushen Quxie,and aminophylline groups(P<0.05). The results of R-value comprehensive evaluation about airway wall thickness,airway smooth muscle hyperplasia,indicators related to airway remodeling in serum and BALF in COPD rats showed that the components compatibility,except for Huatan,Quxie,ECC-BYF Ⅲ,other components compatibility and aminophylline improved the airway remodeling of COPD rats(P<0.05). Buqi Quxie,Fuzheng Huatan,and Buqi Huoxue showed better effects in improving airway remodeling in COPD rats. Conclusion  ECC-BYF Ⅲ and its components compatibility showed different effects on airway remodeling in COPD rats. Buqi Quxie,Fuzheng Huatan,Buqi Huoxie(containing ginsenoside Rh1,astragaloside)showed better effects.

  • 电视录音中主传声器摆位的方法研究

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:电视录音中会存在很多的差异性,主要是和主传声器的摆位有关系,根据声源的位置选择一个合适的传声器十分重要。表面相同的传声器也有着不同的效果,摆放位置虽然不同,但是基本上都是在舞台的中轴线附近来选取的。另外,传声器的指向性以及类型的选择也是根据具体情况来定,正确地摆放主传声器的位置就会为观众营造出不同的环境效果和空间感。本文通过对电视录音中的主传声器摆位方式进行研究,为人们创造出不同效果的音效。

  • 电视台综艺演播室音频系统的设计与应用研究

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:随着科技的发展,受众对节目的要求越来越高,电视台为了吸引受众,就要不断地对综艺演播室的音频系统进行更新设计,以满足制作高清节目的需要。本文对电视台综艺演播室的音频系统的构成与对技术的要求做了一个简要的描述,同时电视台应根据节目的需要和自身的实力来对综艺演播室音频系统进行设计,只有这样,才能设计出符合电视台节目制作要求,具有高性价比的综艺演播室音频系统。

  • 探析数字媒体时代电视媒体的发展之路

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:随着科技的进步,媒介传播技术不断得到发展,我们已经进入数字媒体时代。与此同时,报纸、广播、电视等传统媒体面临生存和发展的考验。手机、互联网等数字媒体的出现使得传统媒体受众数量减少、广告收入下滑。这一现象受到学界和业界的广泛关注,本文在具体实例的基础上,从内容和渠道两个方面,探析在数字媒体时代背景下电视媒体该如何发展。

  • 基于用户潜在兴趣的知识感知传播推荐算法

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2022-05-10 Cooperative journals: 《计算机应用研究》

    Abstract: Applying knowledge graph to recommendation system can make use of semantic relations between entities of knowledge graph to learn user and item representation. The embedding propagation method uses the graph structure of the knowledge graph to learn relevant features, but the semantic dependency between multi-hop entities decreases as the propagation range increases. In order to effectively improve the semantic expression ability of recommendation and improve the accuracy of recommendation, this paper proposes a knowledge-aware propagation recommendation algorithm based on users' potential interests. The model adopts heterogeneous propagation method to disseminate item relevant knowledge and iteratively learn users' potential interests, so as to enhance the representation ability of the model to users and items. Specifically, first, graph embedding layer generate initialize representation of users and items, and in the heterogeneous propagation layer, the knowledge-aware attention mechanism can distinguish the importance of entities in the same layer, so the model can generate the representation of target entities more accurately. Then the user's potential interest propagation can effectively learn the user's higher-order potential interest and enhance the semantic relevance of multi-hop entities. Finally, information decay factor is used in the prediction layer to distinguish the importance of different communication levels and generate the final representation of users and items. Experiments show that the AUC value of the model on the Last. FM and Book-Crossing increases by 2.25% and 4.71% compared with the most advanced baseline, and the F1 value increases by 3.05% and 1.20% respectively, and the Recall@K value is superior to the comparison baseline model. The proposed model can effectively improve the accuracy of recommendation.

  • 民勤绿洲边缘阻沙带表层土壤粒度空间分布特征

    Subjects: Agriculture, Forestry,Livestock & Aquatic Products Science >> Soil Science submitted time 2021-09-14 Cooperative journals: 《干旱区研究》

    Abstract:土壤粒度是风沙活动的重要表征参数。通过野外调查与室内测试,分析了不同空间分布防风固沙林表层土壤粒度的空间分布特征,旨在评价民勤绿洲边缘阻沙带防风固沙功能。结果表明:(1)坝区梭梭-沙拐枣-沙蒿-沙米固沙林表层土壤粒度组成以细砂、中砂、极细砂为主,分别占33.47%、26.08%、18.18%;泉山区白刺+沙蒿+五星蒿固沙林表层土壤粒度组成以细砂、粉粒和极细砂为主,分别占29.62%、21.17%、18.87%;湖区白刺-芦苇-猪毛菜固沙林表层土壤粒度组成以细砂、粉粒和极细砂为主,分别占36.66%、27.98%、22.83%。(2)平均粒径,坝区(2.55Φ)>泉山区(3.5 Φ)>湖区(3.94 Φ),分选性,坝区(1.58 Φ)较差,湖区(2.10 Φ)和泉山区(2.29 Φ)很差。(3)泉山区、湖区表层土壤粒度频率曲线为双峰型,坝区为单峰型,偏度均为极正偏态,峰度表现为很窄。粒度累计分布曲线反映出坝区风沙活动较泉山区、湖区频繁、强烈。阻沙带荒漠植被群落物种组成决定着其防风固沙功能的大小,进而影响其表层土壤的粒度分布特征。建议阻沙带生态防护体系修复时应注重选择固沙能力强的造林树种。

  • 干旱半干旱区城市生态效率时空演变及区域差异分析

    Subjects: Geosciences >> Geography submitted time 2020-06-02 Cooperative journals: 《干旱区地理》

    Abstract: 研究西北干旱半干旱区城市生态效率,对其经济、资源、环境的协调统一以及生态文明建设的推进具有重要的现实意义。以西北干旱半干旱区38个城市为研究对象,运用三阶段DEA方法客观地测度了各城市2005-2016年生态效率,同时运用ESDA方法全面分析了生态效率的区域差异。结果显示:干旱半干旱区城市生态效率普遍较低,并呈现正向全局空间自相关关系;热点区域主要以鸟鲁木齐、克拉玛依等为中心,冷点区域主要以平凉、固原等为中心,热点区域数量呈现先增后减再增的N形变动趋势,冷点区域数量则呈现先减后增再减的倒N形变动趋势。

  • 民勤黑果枸杞形态学特征与土壤因子的关系

    Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-04-26 Cooperative journals: 《干旱区研究》

    Abstract:通过对民勤绿洲外围4种不同立地类型黑果枸杞群落物种组成、生长特征、土壤因子等的调查,分析不同立地类型土壤因子对黑果枸杞生长的影响。结果表明:① 不同立地类型黑果枸杞群落物种结构简单,共出现12科24属28种,存在多个单属单科单种现象,多为适应干旱盐碱化的藜科、蒺藜科植物,无乔木和高大灌木,黑果枸杞在不同立地类型中优势地位明显。② 黑果枸杞群落丰富度指数砾石地高于盐碱地、覆沙地及固定或半固定沙丘地(P<0.05);多样性指数砾石地高于盐碱地,盐碱地高于覆沙地及固定或半固定沙丘地(P<0.05)。③ 不同立地类型黑果枸杞密度表现为:盐碱地>覆沙地>固定或半固定沙丘地>砾石地。株高表现为:固定或半固定沙丘地>盐碱地>覆沙地>砾石地。冠幅表现为:固定或半固定沙丘地>盐碱地>砾石地>覆沙地。④ 土壤速效钾、有效磷、全磷及有机质含量均为盐碱地显著高于其他3个立地类型(P<0.05),全钾、全氮含量在4种不同立地类型之间差异性不显著(P>0.05)。不同土层中土壤因子变化规律不同。⑤ 土壤水分随土层深度的增加变化趋势不同,砾石地和固定或半固定沙丘地中土壤含水率随土层深度的增加而增加,覆沙地随土层深度的增加呈现波动变化,盐碱地随土层深度的增加变化不大。⑥ 黑果枸杞的生长状况和形态学特征株高、冠幅等受土壤水分、土壤氮、磷、钾及有机质等土壤因子的影响和制约,且10~20 cm土层深度土壤因子影响最为密切。

  • 基于树轮生理模型的雪岭云杉径向生长的模拟研究

    Subjects: Geosciences >> Geography submitted time 2020-01-06 Cooperative journals: 《干旱区地理》

    Abstract:雪岭云杉(Picea schrenkiana)是天山山区重要的造林树种,为了解天山山区森林上限树木径向生长对气候环境的响应机制,运用树轮气候学方法,通过采自天山东部巴里坤山雪岭云杉林上限的树芯样本建立的树轮宽度标准化年表,采用VS-oscilloscope模型,模拟雪岭云杉的径向生长过程并揭示了过去55 a以来该过程与环境因子的关系。结果表明:(1)模拟得到的树轮宽度指数与实际树轮宽度指数相关系数为0.645(P<0.01)。两者变化趋势具有较好的一致性,表明模型取得了较好的模拟效果。(2)树木径向生长主要限制因子是4~5月和7~8月的土壤湿度,温度是决定树木生长季开始的主要影响因子,而温度决定的生长速率在宽窄轮的形成上并不明显。(3)模拟的树轮宽度指数与生长结束日期的相关系数是-0.413(P <0.01),说明生长季节的结束日期对树轮宽度的增长有一定的影响。(4)自1984年以来,随着区域气温的逐渐上升,树木生长季的长度有延长的趋势,而树木径向生长却发生衰退现象,1984年以来气温的升高可能是树木生长衰退的主要原因。因而研究从生理角度揭示天山东部森林上限树木径向生长过程中的主要限制因子和限制时段,以期为该区域之后的树轮学研究提供一些借鉴意义。

  • 民勤绿洲边缘积沙带形成的环境条件

    Subjects: Geosciences >> Geography submitted time 2019-11-15 Cooperative journals: 《干旱区地理》

    Abstract:甘肃河西地区经过60多年的防沙治沙,在绿洲边缘形成了一条积沙带。民勤绿洲边缘积沙带高4.8~18.6 m,宽30.4~461.4 m。为什么有的地段积沙带高大,而有的地段积沙带相对矮小,或者有的地段积沙带较宽,而有的地段积沙带较窄?对此,以民勤为研究区,通过对民勤绿洲边缘积沙带进行了调查,运用相关分析等方法和SPSS软件进行了分析。结果表明:(1) 民勤绿洲边缘积沙带按形成方式可分为天然灌丛积沙带、乔木林带积沙带、人工固沙林积沙带3种,其中天然灌丛形成的积沙带相对高大,而农田边缘单纯的乔木林带形成的积沙带最窄。(2) 控制积沙带高度的环境因子主要是积沙带与主风向的夹角,即积沙带与主风向的夹角越小,则积沙带的高度越低。上风向对准风沙口时,则积沙带与主风向的夹角越小,积沙带的宽度亦越小。(3) 典型相关分析结果好于单相关分析。结果显示,积沙带的形态主要是由其宽度、宽高比和断面形状决定的,而影响积沙带形态特征的环境因子主要是上风向是否对准风沙口以及沙源的距离,亦即当上风向未对准风沙口时积沙带较宽且断面积较大,积沙带与上风向沙源距离越小则积沙带越高大。

  • 树轮宽度记录的塔吉克斯坦北部160 a平均最低气温变化

    Subjects: Geosciences >> Other Disciplines of Geosciences submitted time 2019-09-11 Cooperative journals: 《干旱区研究》

    Abstract:利用塔吉克斯坦北部土耳其斯坦圆柏[WTBX](Juniperus turkestanica)[WTBZ]树轮宽度标准化年表与区域气候要素进行相关分析,发现当年2—3月平均最低气温与树木径向生长存在显著相关关系。据此对该地区1857—2016年2—3月平均最低气温进行重建,重建方程的解释量为39.5%,调整自由度后的解释量为37.5%。研究表明:在过去160 a,该地区经历了6个偏暖阶段,1857—1878年、1885—1890年、1907—1915年、1926—1931年、1960—1967年、1994—2016年;5个偏冷阶段,1879—1884年、1891—1906年、1916—1925年、1932—1959年、1968—1993年。空间分析结果表明,研究区2—3月平均最低气温的重建结果可以代表塔吉克斯坦地区过去160 a的2—3月平均最低气温的变化。

  • 民勤绿洲外围不同立地类型黑果枸杞种群分布格局

    Subjects: Geosciences >> Other Disciplines of Geosciences submitted time 2019-09-09 Cooperative journals: 《干旱区研究》

    Abstract: 通过测定石羊河下游民勤绿洲外围4个不同立地类型黑果枸杞群落植被特征和黑果枸杞株数、株高、冠幅等生物学特征,以及黑果枸杞分布格局的点坐标,采用空间点格局分析方法中的Ripley’s K函数,分析了民勤绿洲外围不同立地类型上黑果枸杞空间分布格局。结果表明:① 4个不同立地类型中植被物种数为:砾石地﹥盐碱地﹥固定或半固定沙丘地、覆沙地,植物群落结构比较简单,存在多个科单属单种现象。② 黑果枸杞株数在盐碱地中最多,覆沙地次之,固定或半固定沙丘地和砾石地中最少;而平均株高由高到低依次是固定或半固定沙丘地、盐碱地、覆沙地、砾石地;平均冠幅分布与平均株高类似。③ 在4个样地中,固定或半固定沙丘地和砾石地中的黑果枸杞呈现聚集分布;覆沙地中,黑果枸杞在较小尺度(0.2~0.5 m)呈现聚集分布,在较大尺度(1.5~2.5 m)呈现随机分布;盐碱地中,黑果枸杞种群表现为完全的随机分布。

  • 解释框架对文化混搭产品评价的影响——比较焦点和解释策略的调节效应

    Subjects: Psychology >> Social Psychology submitted time 2018-09-07 Cooperative journals: 《心理学报》

    Abstract: 文化混搭产品因涉及到不同国家的文化符号的同时呈现, 可能导致母国文化的完整性与生命力受到威胁, 引发外国文化入侵母国文化的感知进而降低消费者的产品评价。本研究从文化混搭产品的营销传播视角出发, 基于前人的研究基础之上, 探讨了不同信息表述框架策略的采用会如何影响消费者的文化入侵感知进而影响他们对文化混搭产品的评价, 并重点探究了它可能存在的两个边界条件, 即消费者的比较焦点和企业的不同解释策略。两个实验的结果不仅再一次验证了前人所得出的研究结论, 即文化混搭产品采用“外国文化−母国文化”的框架策略时, 会使消费者产生外国文化改变了母国文化的感知, 导致消费者对产品的评价要显著低于采用“母国文化−外国文化”的框架策略, 其中感知文化入侵起着完全中介的作用。更重要的是, 深入揭示出上述的这种不同文化混搭框架效应只有在启动的是消费者的差异性聚焦以及企业采用的是属性解释策略时才存在, 而当启动的是消费者的相似性聚焦以及企业采用关系解释策略时, 这一效应将会消失。本研究不仅深入剖析出了引发消费者对文化混搭现象产生排斥性反应的内在机理, 拓展了前人研究结论的普适性, 也为企业的文化混搭产品的营销推广提供了有用的实践启示。

  • 卷积神经网络在乐器板材优劣识别中的应用研究

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2018-05-02 Cooperative journals: 《计算机应用研究》

    Abstract: At present, the vibration signal recognition algorithm for national musical instrument plate has the shortcomings of complex feature extraction and time-consuming. To solve this problem, this paper proposed a classification algorithm of wood vibration signal based on convolution neural network, to identify the quality of the musical instrument. Convolution neural network combines feature extraction and classification process to train the neural network, which owns the advantages of high recognition rate and good robustness. Firstly, this paper mainly analyzed and discussed spectrogram characteristics of the extraction of wood vibration signals. Then combining convolution neural network and grid search method, it can adjust the parameters. In order to avoid over-fitting, the final classification results were obtained by using new technologies such as ReLU and Dropout. The experiments showed that the accuracy of the test sample reached 96%, which are obviously better than the traditional method. This method can reduce the error of manual measurement and speed up the selection time of the plate, and provide a more convenient method for the selection of the national musical instrument manufacturing field.

  • 饲粮非纤维性碳水化合物/中性洗涤纤维对黔北麻羊瘤胃发酵参数、血浆生化指标、养分消化率的影响

    Subjects: Biology >> Zoology submitted time 2017-10-23 Cooperative journals: 《动物营养学报》

    Abstract:本试验旨在研究不同饲粮非纤维性碳水化合物(NFC)/中性洗涤纤维(NDF)对黔北麻羊瘤胃发酵参数、血浆生化指标、养分消化率的影响。采用3×3拉丁方试验设计,选取6只健康成年黔北麻羊为试验动物,将其分为3组,每组2个重复,每个重复1只羊。试验Ⅰ组、试验Ⅱ组、试验Ⅲ组饲粮NFC/NDF分别为2.14:1.00、1.05:1.00、0.40:1.00。试验分3期,每期15 d,包括10 d预试期和5 d正试期。检测指标包括:饲粮养分消化率、瘤胃发酵参数(pH、缓冲力、氨态氮和挥发性脂肪酸浓度、纤维素酶活性)、血浆生化指标(脂多糖、白蛋白、尿素氮、葡萄糖含量及过氧化氢酶、谷草转氨酶、超氧化物歧化酶、谷胱甘肽过氧化物酶活性)。结果显示:1)3个试验组干物质采食量差异不显著(P>0.05),试验Ⅲ组各养分消化率均显著低于试验Ⅰ组、试验Ⅱ组(P0.05)。3)试验Ⅰ组、试验Ⅱ组、试验Ⅲ组血浆脂多糖含量依次显著下降(P0.05)。综合来看,过高NFC/NDF对黔北麻羊瘤胃发酵参数和血浆生化指标有不良影响,本试验条件下,饲粮NFC/NDF以1.05:1.00为宜。

  • 重组肺炎克雷伯氏菌转化甘油为聚3-羟基丙酸

    Subjects: Biology >> Bioengineering submitted time 2017-06-01 Cooperative journals: 《中国生物工程杂志》

    Abstract: Poly(3-hydroxypropionate) (P3HP) represents a novel biodegradable and biocompatible polyhydroxyalkanoate. None of currently identified organisms can naturally synthesize P3HP. Two recombinant Klebsiella pneumoniae strains for the production of P3HP were constructed. The propionaldehyde dehydrogenase gene (pduP) from Salmonella enterica serovar typhimurium LT2 and the polyhydroxyalkanoate synthase gene (phaC) from Ralstonia eutropha H16 were cloned by PCR and cloned into vectors. Transformation of vectors into competent K. pneumoniae cells led to two recombinant strains: K. p(pET-tac-pduP-phaC), whereby pduP and phaC shared tac promoter, and K. p(pET-tac-pduP-tac-phaC), whereby pduP and phaC were independently expressed under tac promoter. Using glycerol as the sole carbon source for shake flask fermentation, the strain K. p(pET-tac-pduP-phaC) produced 0.054 g/L of P3HP, by contrast, the strain K. p(pET-tac-pduP-tac-phaC) produced 0.091 g/L of P3HP.