Subjects: Library Science，Information Science >> Library Science submitted time 2023-08-27 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] This paper aims to expound the main ways of open & sharing government data information(OSGDI)in China, America and Britain. Through comparative analysis, it puts forward policy recommendations for OSGDI in China.[Method/process] By using the methods of literature research and comparative analysis, the paper compares and analyzes the safeguard mechanism of OSGDI in China, America and Britain from four aspects of policy and legal system, organization system, platform construction, and implementation and supervision feedback. Finally, it puts forward related suggestions to promote the level of OSGDI.[Result/conclusion] Through the comparative study of the three countries of China, America and Britain, drawing on the beneficial practice of America and Britain, we should speed up the improvement of the regulations and standards of OSGDI, perfect the organization system, construct the open sharing platform of data and information, and explore the effective operating mechanism, in order to excavate "data red profit", create greater public value, promote new public value, and carry out the strategy of "network power" and "digital China" in the era.
Subjects: Library Science，Information Science >> Library Science submitted time 2023-08-26 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] This paper aims to explore the internal mechanism and pattern of open &sharing government data (OSGD), and provide references for improving government data management policy, and promoting trans-boundary integration, and generating incremental data revenue and greater public value.[Method/process] Using questionnaire survey, in-depth interview and other research methods, this paper designed scale system and analyzed empirically. On the basis of verification of related variables, the paper construct a multi-party cooperative model of OSGD based on cross boundary integration, and explained this model.[Result/conclusion] There is a significant correlation among platform, data, mechanism and performance output. At this stage, we should improve the unified platform of OSGD, innovate the data management based on the whole life cycle of the data, in order to realize the data trans-boundary integration, and lay the foundation for promoting the opening and sharing of the government data and the development of "data driven".
Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-08-11 Cooperative journals: 《中国全科医学》
Abstract： Background Coronary heart disease（CHD）is one of the major public health burdens in the world. Although treatment strategies have been developed，but CHD remains a leading cause of morbidity and mortality worldwide. The diagnosis of CHD mainly relies on coronary angiography or contrast-enhanced computed tomography. However，due to the lack of equipment in primary hospitals，early diagnosis and prognosis judgment are relatively difficult. Therefore，the search for relatively simple and easy-to-obtain laboratory indicators is conducive to providing basis for primary care physicians to diagnose and treat CHD. Objective To investigate the correlation of serum interleukin-6（IL-6）and fasting blood glucose（FPG）levels with the degree and clinical classification of coronary stenosis，number of lesions and adverse cardiovascular events in patients with CHD. Methods CHD patients admitted to the Fifth Affiliated Hospital of Xinjiang Medical University from September to November 2020 were included as the study objects，and their general data and laboratory test results were collected. According to Gensini score criteria，the patients were divided into the mild stenosis group（group A，Gensini score ≤ 33.25 points，n=40）and moderate and severe stenosis group（group B，Gensini score>33.25 points，n=40）based on the Gensini scoring criteria. According to the results of coronary angiography results，patients were divided into the single-vessel lesion group （n=28），double-vessel lesion group（n=21）and multi-vessel lesion group（number of lesion branch ≥ 3，n=31）based on the number of lesions. According to the clinical classification，patients were divided into stable angina group（n=34）and acute coronary syndrome group（n=46）. Spearman rank correlation analysis was used to explore the relationship of serum IL-6， FPG with relevant data of patients. Survival curves of patients were plotted using the Kaplan-Meier method，and the comparison of survival curves was performed by Log-rank test. Univariate and multivariate COX proportional hazard regression analyses were used to explore the factors influencing the risk of adverse cardiovascular events in patients with CHD. The receiver operating characteristic（ROC） curve of IL-6 predicting the occurrence of adverse events was plotted. Results IL-6 and FPG in group A were lower than those in group B，IL-6 in the multi-vessel lesion group was higher than that in the single-vessel lesion group， FPG was higher than that in double-vessel lesion group，and IL-6 and FPG in acute coronary syndrome group was higher than that in stable angina group，with statistical significance（P<0.05）. Spearman rank correlation analysis showed that serum IL-6 was correlated with clinical type，number of coronary lesions，Gensini score，gender，TG and FPG，and FPG was correlated with clinical type，number of coronary lesions，Gensini score，age and IL-6（P<0.05）. The patients were divided into IL- 6>45.8 ng/L group（n=39）and IL-6 ≤ 45.8 ng/L group（n=41）according to the median IL-6 expression level（45.8 ng/L）， and the upper limit of normal FPG（6.1 mmol/L）was used as the grouping standard to divide the patients into FPG>6.1 mmol/L group（n=36）and FPG ≤ 6.1 mmol/L group（n=44）. Log-rank test results showed that the incidence of adverse cardiovascular events in IL-6>45.8 ng/L group was higher than that in IL-6 ≤ 45.8 ng/L group（76.9% vs. 36.6%；c2=16.075，P < 0.001）， FPG>6.1 mmol/L group had a higher incidence of adverse cardiovascular events than FPG ≤ 6.1 mmol/L group（69.4% vs. 45.5%；c2=4.292，P=0.038）. Multivariate Cox proportional hazard regression analysis showed that IL-6 was a significant factor in adverse cardiovascular events〔HR=2.396，95%CI=（1.203-6.054），P<0.05〕. The area under ROC curve of IL-6 for predicting adverse cardiovascular events was 0.769（95%CI（0.658-0.880），the best optimal value was 40.97 ng/L，with the sensitivity and specificity of 0.867 and 0.683. Conclusion Serum IL-6 and FPG levels are associated with CHD and its poor prognosis. Serum IL-6 is an independent risk factor for adverse cardiovascular events in patients with CHD.
Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-04-03 Cooperative journals: 《中国全科医学》
Abstract： Background Coronary heart disease（CHD） is the leading cause of death world wide.Coronary angiography is often used as an effective approach for the diagnosis of coronary heart disease（CHD）. However，coronary angiography accounts for relatively low percentagein examination approaches due to the limitation of various conditions in primary care，and more meaningful biomarkers need to be explored to provide a basis for primary care physicians to diagnose and treat CHD. In the previous study of our research group，it is found that early growth response 3 （Egr3）gene may be a susceptibility factor in the heterogeneity of CHD pathogenesis，and there are few reports on the correlation between CHD and Egr3 gene and inflammatory biomarkers. Objective To investigate the correlation between Egr3，interleukin-6 （IL-6）and CHD，as well as their expression levels and the severity of coronary stenosis，so as to provide a favorable laboratory basis for clinical diagnosis and treatment inprimary care. Methods A total of 110 patients who admitted to the Fifth Affiliated Hospital of Xinjiang Medical University for CHD symptoms and completed coronary artery angiography （CAG） during June to December 2021 were collected and divided into the mild stenosis group（group A ≤ 52 points， n=50），moderate-severe stenosis group（group B>52 points， n=30） and control group（group C， n=30）according to the CAG results and median Gensini score（52 points）. Serum Egr3 and IL-6 levels of the included patients were measured by enzyme-linked immunosorbent assay. Results The IL-6 level in group B was higher than that in group A and group C （ P<0.05），and Egr3 expression level in the group A and group B was higher than that in group C，respectively（ P<0.05）；The area under the ROC curve of Egr3 expression level in the diagnosis of coronary heart disease was 0.648，with a sensitivity of 35.0% and specificity of 93.3%. There was positive correlation between IL-6 and Egr3 in CHD patients （ r=0.231， P<0.01）；Egr3 and IL-6 levels were positively correlated with Gensini score （ r=0.39，0.317， P<0.01）. Conclusions Egr3 has good specificity for the diagnosis of CHD，and the expression levels of Egr3 and IL-6 were positively correlated with the severity of coronary stenosis.
Subjects: Biology >> Botany submitted time 2022-10-27 Cooperative journals: 《广西植物》
Abstract： The pollen receptor like kinase (PRK) family, an LRR receptor-like protein kinase, not only played a role in pollen development and fertilization, but also played a role in stress response. Based on the analysis of transcriptome data that generated in our previous study, we found that AhPRK4 was an aluminum-responsive gene. To explore the role of AhPRK4 in response to Al stress, we analyzed the expression of AhPRK4 by qRT-PCR in ‘ZH2’ (Al-sensitive) and ‘99-1507’ (Al-tolerant), clarified the protein structure and genetic relationship of AhPRK4 by sequence analysis, phylogenetic tress construction and other genetic analysis, constructed the recombinant plasmid by homologous recombination, obtained the intracellular domain recombinant protein of AhPRK4 by prokaryotic expression technology and determined the activity of the recombinant protein by incubation with phosphorylated antibodys. The results were as follows: (1) The transcription level of AhPRK4 was up-regulated after different aluminum treatment times and different aluminum concentrations, indicating that AhPRK4 was an aluminum inducible gene; (2) The AhPRK4 protein had 673 amino acids with transmembrane domain, signal peptide and phosphorylation active sites, belonging to the LRR-III protein kinase family; (3) The GSTAhPRK4- CD recombinant protein was induced in vitro and verified by Western Blot. And the recombinant protein had phosphorylated on both serine/threonine and tyrosine residues, but had no significant auto-phosphorylation activity. In conclusion, AhPRK4 was an Al responsive gene, which participated in the regulation of short-term Al stress and was phosphorylated in vitro.
Subjects: Geosciences >> Atmospheric Sciences submitted time 2022-04-12 Cooperative journals: 《干旱区地理》
Abstract：基于20032019年MODIS Aqua Aerosol L2反演的新疆大气气溶胶光学厚度（Aerosol opt⁃ical depth，AOD）产品，选取中国气象局大气气溶胶光学特性观测网（Chinese aerosol optical property network，CAOPNET）乌鲁木齐地面观测站点CE-318太阳光度计观测数据与MODIS AOD数据进行对比验证，通过Spearman秩相关检验，研究近17 a新疆AOD的年均值变化，并提取14个AOD高值区，以分析其逐年线性变化趋势，最后得到近17 a新疆AOD的时空变化特征。结果表明：（1）MO⁃ DIS AOD与CAOPNET AOD两者具有良好的相关性，相关系数（r）为0.6381，符合期望误差（Expect⁃ed error，EE）的数据占65%，MODIS AOD产品与CAOPNET AOD数据对比表明，MODIS AOD产品在新疆反演精度较高。（2）20032019年新疆AOD分布地域差异明显，南疆地区均值明显高于北疆地区。第一高值区位于南疆塔里木盆地，其边缘地带年均值超过0.6，第二高值区位于天山北坡经济带，年均值超过0.3。20032019年，新疆除石河子和乌昌地区AOD呈现显著上升以外，大部分地区AOD年变化趋势不明显。（3）20032019年新疆四季AOD差异非常显著，总体表现为春季>夏季>冬季>秋季。南疆地区四季AOD均值变化比北疆地区大。（4）新疆AOD月均值范围为0.11~0.51，整体呈14月逐月增加，512月逐月下降的单峰型变化特征，4月AOD月均值达到峰值，12月AOD月均值最小。本研究结果可为新疆大气环境治理和未来污染防治提供一定的科学依据。
Subjects: Geosciences >> Atmospheric Sciences submitted time 2022-01-21 Cooperative journals: 《干旱区地理》
Abstract：利用20102019年新疆14个探空气象站资料统计分析了近10 a大气最大混合层高度（下文简称混合层高度）、通风量、边界层平均风速及大气自净能力指数的时空分布特征，探讨了各物理参数与空气质量的关系。结果表明：（1）以上参数的逐月分布均呈倒V型，表现为夏半年大、冬半年小，即新疆的大气扩散能力在夏季最强、冬季最弱，其中混合层高度和通风量在冬、夏季差距悬殊。（2）南疆大气扩散能力普遍比北疆好，无论冬夏南疆的自净能力、通风量、混合层高度均大于北疆。（3）北疆除阿勒泰站外，其余站点上述物理参数均与空气质量指数（Air quality index，AQI）呈显著负相关，即大气扩散能力越强，空气质量越好，而南疆只有和田站通过了0.01的置信度检验，但两者呈正相关，即大气扩散能力越强，空气质量越差，这归因于南北疆不同的大气污染来源。
Subjects: Biology >> Botany >> Applied botany submitted time 2021-11-04 Cooperative journals: 《广西植物》
Abstract： Stephania kwangsiensis, a vine plant of the Stephaniaceae family, is mainly spread in Guangxi, China. The roots of S. kwangsiensis, “Jin Bu Huan” in Chinese, is often used for sedative, insecticidal, anti-inflammatory, anti-tumor, antiviral, anti-bacterial, as well as for the treatment of Alzheimer’s disease. In order to make full use of the title plant resources, clarify its chemical components, and find the relevant active compounds, the methanol extracts of non-medicinal parts of this plant was isolated using various chromatographic methods such as positive phase Sephadex LH-20, positive phase silica gel, positive phase polyamide, and MCI gel CHP 20P. The structures of the isolated components were determined by MS, 1H NMR, 13C NMR, and other spectroscopic data analysis, as well as comparison with relevant literatures. The activities of the isolated compounds from S. kwangsiensis against bacteria (Escherichia coli, Staphylococcus aureus, Bacillus subtilis) and fungi (Fusarium oxysporum) were evaluated using filter paper method. The results were as follows: (1) 10 compounds obtained from the non-medicinal parts of this plant were identified as vomifoliol (1), grasshopper ketone (2), isocorydine(3),2-O-β-D-glucopyranosyl-D-arabinitol(4),(9S,12S,13S)-trihydroxyoctadeca-(10E,15Z)-dienoic acid (5), magnoflorine (6), corchoionoside C (7), tormentic acid (8), corydine (9), and crebanine (10). Among of them, compounds 1, 2, 4, 5, 6, 7 and 8 were isolated from this plant for the first time. Compounds 1, 2, 4, 5, 7 and 8 were firstly obtained from this genus plants. And compound 4 was found from natural products for the first time. (2) At concentration of 6 mg·mL-1, Compounds 1, 2 and 5 show weak antibacterial activities against Escherichia coli; Compound 2 exhibits weak antibacterial activities against Staphylococcus aureus; Compounds 3 and 8 display weak antibacterial activities against Bacillus subtilis. The non-medicinal parts of Stephania kwangsiensis contains large numbers of active components and have the potential of development and utilization.
Subjects: Biology >> Botany >> Applied botany submitted time 2021-04-29 Cooperative journals: 《广西植物》
Abstract： Flavonoid-C- glycosides, as one of the effective components in Premna fulva, have the effect of antigen-induced arthritis. The enrichment and purification process of five flavonoid-C-glycosides as in P. fulva stems is preferred. Through static adsorption and desorption experiments on 13 kinds of macroporous resins with five flavonoid-C- glycosides in P. fulva stems as the index,a suitable macroporous resin was selected, and the results were tested by the HPLC, and then the orthogonal process was used to optimize the enrichment and purification conditions. The results showed that XAD-16N macroporous resin has a good adsorption and desorption effect on the five flavonoid -C-glycosides in P. fulva stems. Through single factor screening and orthogonal process optimization, the best enrichment and purification process is finally determined as follows: the loading concentration is 0.5 times the original extract diluted, the loading flow rate is 2 BV穐-1, and the eluent concentration is 60 % ethanol. The content of five flavonoid-C-glycosides increased from 1.73 % (in the original plant) to 14.5 %, an increase of 7.38 times. The results showed that the selected extraction process is stable and feasible, and the selected macroporous resin has a good separation and purification effect, which provides a reference for the drug development of P. fulva stems.
Subjects: Geosciences >> Geography submitted time 2020-12-17 Cooperative journals: 《干旱区研究》
Abstract：作物系数（Kc）对提高实际蒸散量的估算精度及区域水资源调控具有重要意义。通过Landsat 8数据计算归一化植被指数（NDVI）、土壤调整植被指数（SAVI）和简单比值植被指数（SR），结合2017年地面实测土壤含水量（SM）和叶面积指数（LAI），通过逐步回归分析建立科尔沁地区草甸及沙丘试验区的作物系数估算模型，利用2018年模拟作物系数值与FAO 56 P-M模型计算所得潜在蒸散量（ET0）相乘，得到实际蒸散量（ETa）的估算值，与涡度相关系统所测实际蒸散量进行对比验证。结果表明：（1）草甸和沙丘试验区的作物系数在生长季内的变化趋势与植被指数及SM具有一致性，说明了基于这些指标建立Kc估算模型的可行性；（2）相关性分析中，草甸试验区的Kc与SR相关性不显著（P>0.05），沙丘试验区Kc与SR相关性较低（0.46），故剔除该因子；（3）逐步回归分析中进一步剔除不显著因子后建立草甸及沙丘作物系数估算模型，模型的均方根误差、修正的决定系数分别为0.06、0.84和0.12、0.71；（4）经涡度相关数据验证，基于Kc估算模型计算的ETa在草甸和沙丘试验区均取得较好的模拟效果。
Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-07-20 Cooperative journals: 《干旱区研究》
Abstract：为揭示锡林河流域上游蒸散发（ET）变化规律及其时空分布特征，采用Landsat 8数据、气象观测数据和SEBAL模型估算2015—2017年共12期植物生长季的蒸散量，并分析其时空格局及影响因素。结果表明：① 研究区模型反演参数值与实测值拟合效果良好，地表净辐射（Rn）、土壤热通量（G）、ET的决定系数（R2）分别为0.80、0.65和0.86；② 同一时段的Rn和ET空间分布具有较高的一致性，整体呈现东高西低的趋势，具有显著的时空分异特征。4月日ET值在0~4.67 mm，5—7月日ET值整体呈增加趋势，最大可达10.32 mm，9—10月日ET值减少至0~3.34 mm；③ 不同土地利用类型蒸散量依次为：水体>沼泽地>耕地>草地>沙地>农村居民点，ET值与日平均气温（T）、饱和水气压差（VPD）、Rn呈正相关，与空气湿度（RH）呈负相关，对Rn的变化最为敏感。
Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-06-19 Cooperative journals: 《干旱区研究》
Abstract：为全面揭示锡林河流域上游河谷湿地格局变化过程及驱动因素，选取1989—2015年12景Landsat卫星影像为数据源，采用质心迁移模型和景观指数方法，研究了区域湿地景观的组成及演变趋势，并探讨了湿地景观变化的主要驱动因子。结果表明：① 1989—2015年，锡林河上游湿地面积整体呈减小趋势，变化率为-1.21 km2·a-1；湿地面积占比在2.55%～3.75%。湿地质心整体向西北方向迁移，斑块面积在南北方向呈缩小趋势，而在东西方向呈延长趋势。② 类型水平上，1995—2006年流域湿地斑块数量变化剧烈，1989—2000年斑块数量增加，表明景观破碎度增大，2011—2015年斑块数量呈下降趋势，景观斑块向规则化和集中化趋势发展；景观水平上，湿地最大斑块所占比例减少，斑块趋于复杂化，景观破碎度增大，香农多样性、香农均匀度指数整体呈减少趋势，湿地景观分布向均衡方向发展。③ 湿地面积对人口数量和牲畜量响应较为敏感，过度放牧是导致该区域湿地不断萎缩、景观多样性改变的关键驱动力。
Subjects: Biology >> Zoology submitted time 2018-12-24 Cooperative journals: 《动物营养学报》
Abstract：发酵饲料桑粉；宁乡花猪；生长性能；肉品质；血清生化指标
Subjects: Biology >> Botany >> Applied botany submitted time 2018-10-26 Cooperative journals: 《广西植物》
Abstract： Enteromorpha intestinalis polysaccharides carboxymethylation (EIPC) were made in the NaOH-chloroacetic acid chemical reaction system to obtain carboxymethylated gut polysaccharides with different degrees of substitution. The degree of substitution was affected by the sodium hydroxide concentration, the reaction temperature and the reaction time. When the sodium hydroxide concentration was 20%, the reaction temperature was 60 °C, and the reaction time was 3 h, the maximum degree of substitution for carboxymethylation was 0.781. The antioxidant activity of different Enteromorpha intesinalis polysaccharide carboxymethylation was evaluated by in vitro antioxidant. At the concentration of EPIC was 1.6 mg·mL-1, the scavenging activity to hydroxyl free radical and superoxide anion free radical were 44.45% and 51.98%, the ability of scavenging DPPH free radical and reducing ability were 16.75% and 0.4576. Compared with the pre-modification, the scavenging ability of hydroxyl radicals and superoxide anion was greatly improved, and the carboxymethylation modification had a weakening effect on DPPH free radicals and reducing power of polysaccharides. The above results indicate that the structural changes of the polysaccharides caused by carboxymethylation can increase its antioxidant activity.
Subjects: Biology >> Ecology submitted time 2017-11-29 Cooperative journals: 《中国生态农业学报》
Abstract： Anthocyanins are important antioxidant molecules that help protect plants from reactive oxygen species (ROS) damage. Especially under adversity conditions, the regulation of Suc in plants depends on its ability to induce the accumulation of anthocyanins. To reveal the intrinsic relationship between photosynthetic and anthocyanin-regulated pathways of the over-expressing maize C4-phosphoenolpyruvate carboxylate (PEPC, EC 4.1.1.31) gene rice (PC) in drought tolerance, PC and untransformed wild-type (WT) acted as materials, were treated with 50 μmol∙L-1 photosynthetic inhibitor DCMU for 1h, and the performance of the rice seedlings in the 4-5 leaf stage was observed under 12% PEG-6000 simulated drought treatment. The results showed that the relative water content of WT and PC was significantly reduced under DCMU treatment, and PC was significantly higher than WT under 12% PEG-6000 simulated drought treatment, which was accompanied by the higher anthocyanin content in PC lines. From the photosynthetic data, compared with 12% PEG-6000 alone, DCMU combined with 12% PEG-6000 significantly inhibited the net photosynthetic rate, stomatal conductance, intercellular CO2 and carboxylation efficiency of the two rice lines, but the PC lines was significantly higher than WT. Meanwhile, DCMU combined with 12% PEG-6000 treatment down-regulated the content of endogenous sucrose in the two materials, but the sucrose content in PC lines was significantly higher than that in WT. Further studies showed that higher sucrose levels in PC were associated with higher levels of transcription with, bHLH(OsB1, OsB2), R2R3-MYB(OsC1), COP1(Constitutively photomorphogenic 1), HY5(Elongated hypocotyl 5), OsPAL, OsCHI, OsCHS, OsF3H, OsF3’H, OsDFR, OsANS to synthesize more anthocyanin, it can synthesize more anthocyanins to enhance water retention capacity. In addition, PC rice can sense drought signals through NO and Ca2+, which involved in the regulation of transcription factors, and then participate in the regulation of anthocyanin synthesis gene, synthesis of more anthocyanin, thereby enhancing the response of PC rice under drought stress to enhance the water retention capacity, keep the photosynthetic capacity stable and finally bear drought. Therefore, it is beneficial in the molecular breeding of “C4 Rice” and the study the symphony between high yield and resistance in plants to open a new vision.
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