Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2024-04-25 Cooperative journals: 《中国全科医学》
LI Songjiao
LEI Kangchen
HUANG Hongwen
SONG Jiali
CHANG Yinghui
FAN Xiaonong
LI Li
DU Yuzheng
LIU Jian
CAI Xinru
BIAN Lina
MENG Lina
SONG Qian
SHEN Yan
GE Wenyi
LIU Wei
LI Yibing
JIA Hongbo
GAO Ying
MA Congcong
Abstract： Background Long COVID is a common problem in the recovery period of coronavirus disease（COVID-19）. The prevention and treatment of long COVID has become the focus of the medical fields of COVID-19. It is important to clarify the situation of long COVID in China and find out the follow-up research route，thus providing evidence-based evidence for clinical practice. Objective To explore the characteristics of long COVID in China，aiming to provide references for the follow#2;up research.Methods From January 2023 to August 2023，a self-made survey questionnaire was used to investigate the current situation of long COVID in China. The questionnaire included general information，such as gender and age，treatment expectations，symptoms and signs in acute and recovery period，etc. Results A total of 1001 questionnaires were collected， including 901 people infected with severe acute respiratory syndrome coronavirus 2（SARS-CoV-2），and 585（64.9%） people with long COVID. Binary Logistic regression analysis showed that female（OR=2.000，95% CI=1.477-2.705，P<0.05 ），history of cancer（OR=4.424，95% CI=1.316-14.868，P<0.05 ），and retirement（OR=1.527，95% CI=1.048-2.224， P<0.05）were risk factors for long COVID. Among the 19 symptoms and signs of long COVID，the top three were fatigue（341 people），decrease of memory，comprehension and attention（274 people），and insomnia（217 people）. Low back pain was the leading pain symptom（201 people）. Hair loss was the number one sign to be difficult to self-healing（58.57%）. Acupuncture（55.73%）was the top 1 willingness of treatment，followed by Chinese herbal decoction（53.68%），Chinese traditional patent medicine（47.01 %），Western medicine（24.79%），intravenous drip（12.14%），and hospitalization（11.97%）. Conclusion The incidence of long COVID is relatively high in China. Acupuncture therapy enjoys a widespread favor among patients. It is recommended to carry out targeted research to enhance the clinical evidence for the prevention and treatment of acupuncture therapy. Women，cancer patients，and retired individuals（elderly people）are high-risk groups for long COVID， and low immune function is a common feature among them. It is suggested to establish a database incorporating these populations and conduct cohort studies on the prevention of long COVID through acupuncture. Fatigue，insomnia，and low back pain are more representative symptoms of long COVID，and randomized controlled studies on acupuncture treatment for these three symptoms at first are recommended.
Subjects: Geosciences >> Geography submitted time 2023-12-16 Cooperative journals: 《干旱区研究》
Abstract： This study used yield and water and fertilizer usage efficiency as targets to explore a magnetized water fertilization system suitable for tomato processing via drip irrigation under film. Four magnetized water samples with an intensity of 0 Gs (M0), 2000 Gs (M1), 3000 Gs (M2), and 4000 Gs (M3) as well as three nitrogen application levels of 200 kg N·hm−2 (N1), 250 kg N·hm−2 (N2), and 300 kg N·hm−2 (N3) were set up, and a split zone test design was adopted. Field experiments were conducted. By monitoring the soil moisture content, plant height, stem diameter, and above- ground biomass during the growth period of processed tomatoes, combined with the final yield index, the effects of magnetic nitrogen combination on the water and fertilizer usage efficiency of processed tomatoes were explored. The results showed that magnetized water drip irrigation significantly increased soil moisture content and soil water storage. Magnetic nitrogen coupling was also shown to significantly increase the soil moisture content in the 20- 40 cm soil layer. When the magnetized water intensity was 2270-3678 Gs and the nitrogen rate was 220-230 kg·hm-2, the growth of processed tomatoes was promoted. However, when the magnetization intensity was greater than 4000 Gs and the nitrogen rate was more than 250 kg · hm- 2, the growth of processed tomatoes could not be further improved. As magnetization was increased, the yield and water and fertilizer use efficiency of processed tomatoes increased before decreasing. As the nitrogen application rate was increased, the yield and water use efficiency increased, but the partial productivity of nitrogen fertilizer decreased. Among them, the M2N3 treatment had the highest yield and water use efficiency (169.67 t ·hm- 2 and 35.61 kg ·m- 3), while the M2N1 treatment had the highest nitrogen partial productivity (822.54 kg·kg-1). Using regression and spatial analyses, the magnetic nitrogen range of yield, water use efficiency, and nitrogen partial productivity was 2270-3678 Gs and 220-230 kg N·hm- 2. This study can provide theoretical support for the scientific application of magnetized water and nitrogen fertilizer in tomato processing in Xinjiang and provide scientific guidance for optimizing the magnetic nitrogen combination configuration to improve the yield of tomato processing.
Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc. submitted time 2022-11-16 Cooperative journals: 《中国全科医学》
Abstract：
Background During the global COVID-19 pandemic, wearing masks and maintaining social distancing have become common protective measures. However, there is no comprehensive understanding of the physiological changes caused by patients with chronic obstructive pulmonary disease (COPD) wearing masks. Objective To explore and compare the physiological effects of wearing surgical mask and N95 mask on patients with COPD. Methods Thirty patients with COPD were recruited. The changes of blood gas analysis and subjective perception were monitored through randomized controlled and two-phase crossover studies, and the physiological changes after wearing surgical masks and N95 masks were evaluated. Results All 30 subjects completed the trial. Compared with the surgical mask group, the changes in potential of hydrogen (pH)[ (-0.012±0.015) vs (-0.004±0.010)] in the N95 mask group and the arterial partial pressure of carbon dioxide (PaCO2) [(1.337±1.306 ) mmHg vs (0.250±1.251) mmHg)] and arterial partial pressure of oxygen (PaO2) [(10.433±10.546) mmHg vs (4.000±9.516) mmHg] were significantly increased (P=0.001, P=0.001 and P=0.002). Compared with wearing surgical masks, the relative risk (RR) of COPD subjects wearing N95 masks for dyspnea was 1.563 [95%CI (1.078-2.264)], which was statistically significant (P=0.012). Conclusion Compared with wearing surgical masks, COPD patients wearing N95 masks will affect gas exchange and cause dyspnea.
Subjects: Geosciences >> Other Disciplines of Geosciences submitted time 2019-09-11 Cooperative journals: 《干旱区地理》
Abstract：利用极值Ⅰ型分布和WeiBull分布研究了新疆阿勒泰闹海风区冬季风的极值分布、平均风速概率分布、引发风吹雪的风时数。利用极值、平均概率分布面域、风吹雪时数来量化风吹雪的强度，并将计算得出的风吹雪防治工程设计量级，纳入风吹雪影响区域内的公路设计中。结果表明：通过WeiBull分布的平均风速和风吹雪有效时间分布来计算防雪工程量级是一种公路风吹雪防治工程的计算方法，防雪工程的设计并没有明确的以再现期为指标的设计量级，仅存在防治灾害的量级。
Subjects: Biology >> Botany >> Applied botany submitted time 2018-12-04 Cooperative journals: 《广西植物》
Abstract：圆叶牵牛植物资源丰富但全草少有研究，对其进行系统的化学成分与生物活性认识很有必要。本文对采自云南大理的圆叶牵牛干燥全草化学成分进行了系统的研究。通过 75%乙醇冷浸提取，浸膏以水分散，依次以乙酸乙酯和正丁醇萃取。采用硅胶、Sephadex LH-20、RP-18 等多种材料柱层析结合重结晶等方法，从圆叶牵牛醇提物乙酸乙酯部分分离得到 12个单体化合物，运用现代波谱学技术分别鉴定为木栓酮（1），β-木栓醇（2），β-香树脂醇（3），α-香树脂醇（4），6β-羟基豆甾-4-烯-3-酮（5），胡萝卜苷（6），β-谷甾醇（7），豆甾醇（8），7-羟基香豆素（9），对香豆酸-对羟基苯乙醇酯（10），山奈酚香豆酰基葡萄吡喃糖苷（11），单棕榈酸甘油酯（12）。化合物 2-5、10-12 为首次从该属植物中分离得到。
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》
Abstract： Objective To investigate the effects of triptolide on Notch receptor and ligand expressions in rats with adjuvant-induced arthritis (AA). Methods Forty rats were randomly divided into normal control (NC) group, model (MC) group, methotrexate group and triptolide groups. Rat models of AA were established by an intradermal injection of 0.1 mL Freund's complete adjuvant into the right paw. Twelve days after the injection, the rats were treated with corresponding drugs for 30 days; the rats in NC group and MC group were given saline only. Paw edema volume (E), arthritis index (AI), pulmonary function, histomorphologies, and Notch receptor/ligand expression in the lung tissue were analyzed after the treatments. Results Compared with the NC group, E, AI, Notch3, Notch4, and Delta1 expressions in the lung tissues significantly increased while pulmonary function and pulmonary expressions of Notch1, Jagged1, and Jagged2 significantly decreased the model rats (P<0.01). Compared with the MC group, triptolide-treated rats showed significantly improved pulmonary functions, increased expressions of Notch1, Jagged1, and Jagged2 and decreased expressions of Notch3, Notch4, and Delta1 in the lungs (P<0.05, P<0.01); the therapeutic effect of triptolide was better than that of methotrexate. Conclusion Triptolide can reduce inflammatory reaction and immune complex deposition to improve joint and pulmonary symptoms in rats with AA possibly by up-regulating the expressions of Notch3, Notch4, and Delta1 and down-regulating the expressions of Jagged1, Jagged2, and Notch1.
Subjects: Library Science，Information Science >> Information Science submitted time 2017-11-08 Cooperative journals: 《数据分析与知识发现》
Abstract：【目的】为解决传统的文本聚类无法充分挖掘文本资源语义信息以及相似度矩阵高维性、稀疏性等问题,并进一步改善文本聚类质量, 提出基于语义相似度的文本聚类方法。【方法】通过《同义词词林扩展版》计算词语的语义相似度并得到文本语义相似度矩阵, 根据文本语义相似度矩阵进行谱聚类, 将文本聚集为文本簇。【结果】利用复旦大学文本语料库与搜狗文本语料库中的文本资源作为数据来源分别对传统聚类算法与本文提出的算法进行实验, 结果表明, 当聚类个数为10 时, 本文算法的准确率最高, 并且Purity 值高于传统聚类算法的Purity 值。【局限】《同义词词林扩展版》中包含的领域术语不完整, 部分相似度计算结果需要手工进行调整。【结论】该方法考虑了词语间语义关系, 充分挖掘文本主体潜在信息, 并且改善了聚类质量, 为文本聚类和推荐提供了一条新途径。
Subjects: Library Science，Information Science >> Information Science submitted time 2017-11-08 Cooperative journals: 《数据分析与知识发现》
Abstract：【目的】解决传统数字文献资源内容服务推荐中无法充分挖掘资源语义信息等问题。【方法】通过设定本体推理规则对用户查询关键词进行语义扩展,提出一种新的语义相似度计算方法计算文献资源内容相似度。按照相似度大小对搜索结果进行排序,将排名较高的文献推荐给目标用户。【结果】实验结果证明,该方法能够较准确地计算语义相似度,并能够对用户需求进行有效推荐。【局限】缺少对数字资源的大规模采集,实验案例较少。【结论】该方法充分挖掘数字文献资源的语义信息并进行有效推荐,为数字资源内容服务推荐提供一种新思路。
Subjects: Library Science，Information Science >> Information Science submitted time 2017-10-11 Cooperative journals: 《数据分析与知识发现》
Abstract：【目的】基于人-信息-技术互动的视角构建数字图书馆微服务评价指标体系, 旨在为数字图书馆微服务建设提供理论依据和评判标准。【方法】提出基于聚类方法的群组AHP 方法, 利用其构造判断矩阵, 对数字图书馆微服务指标体系进行测评, 并选用模糊数学中隶属度函数作为标度系统对国内外10个具有代表性的数字图书馆进行实证研究。【结果】实证结果表明, 指标体系具有实际应用价值和较强的可操作性, 能更好地指导数字图书馆进行微服务建设。【局限】评价指标、评价标准、指标权重等还需根据各数字图书馆微服务的具体情况、具体问题进一步深入分析。实证研究的样本量较少, 结论具有局限性, 指标的确定和分值的给定(采用少数专家打分方式)带有主观性。【结论】在理论层面, 基于人-信息-技术互动视角构建的评价指标体系, 为数字图书馆微服务建设提供新的研究视角; 在实践应用层面, 通过对微服务的评价提升数字图书馆微服务质量和效率, 从而达到满足用户需求和期望的目标。
Subjects: Biology >> Zoology submitted time 2017-10-10 Cooperative journals: 《动物营养学报》
Abstract：本试验旨在研究夏季高温条件下饲粮中添加刺梨提取物对皖西白鹅生长性能、脂质代谢及肝脏中热应激蛋白70（HSP70）基因表达的影响。挑选28日龄、体重相近的健康皖西白鹅150只，随机分成3组，即对照组、试验1组和试验2组，每组5个重复，每个重复10只鹅。对照组试验鹅饲喂基础饲粮，试验1组和试验2组试验鹅分别饲喂在基础饲粮中添加100和200 mL/kg刺梨提取物的试验饲粮。预试期7 d，正试期14 d，试验期间最高气温37 ℃，最低气温24 ℃，日平均气温31.6 ℃。饲喂2周后，每个重复挑1只鹅屠宰，采集血样，并分离出肝脏，测定血清脂质代谢指标和肝脏中HSP70基因的相对表达量。结果表明：饲粮添加刺梨提取物对皖西白鹅的采食量和平均日增重均无显著影响（P>0.05），但添加200 mL/kg刺梨提取物可显著降低料重比(P0.05）；与对照组相比，试验1组和试验2组肝脏中HSP70基因的相对表达量均极显著提高（P＜0.01），同时试验1组肝脏中HSP70基因的相对表达量还极显著高于试验2组（P＜0.01）。由此得出，在夏季高温条件下，在皖西白鹅饲粮中添加刺梨提取物可提高饲料转化率、调节脂质代谢、上调肝脏中HSP70基因的表达，具有较明显的抗应激效果，且添加量为100 mL/kg时的抗应激效果优于添加量为200 mL/kg时。
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